Human Anti-GZMB Recombinant Antibody (clone Fv17); scFv Fragment (CAT#: FAMAB-0137-YC-S(P))
Granzyme B, a neutral serine protease, has been demonstrated to be a pivotal molecule for protective immunity against viral infection and cellular malignant transformation. Provided are single-chain Fv antibodies specific for granzyme B, as versatile alternatives and complementary reagents to currently available monoclonal antibodies. Owing to the availability of its DNA sequence and large scale production capability, Fv17 should be a superior reagent for monitoring granzyme B expression in natural killer cells and antigen specific CD8 T cell immunity.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Normal Tissue
RNA Expression
Figure 1 Bone marrow
(Hematopoietic cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3418/10586_B_4_4.jpg
(Hematopoietic cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3418/10586_B_4_4.jpg
Figure 2 Lymph node
(Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3418/10586_A_7_8.jpg
(Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3418/10586_A_7_8.jpg
Figure 3 RNA cell line category: Cell line enriched (HMC-1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000100453-GZMB
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000100453-GZMB
Specifications
- Host Species
- Human
- Derivation
- Phage display library
- Type
- Human scFv
- Specificity
- Human GZMB
- Species Reactivity
- Human
- Clone
- Fv17
- Applications
- ELISA, FC, WB, IP
- Related Disease
- Virus infection
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- C11; HLP; CCPI; CGL1; CSPB; SECT; CGL-1; CSP-B; CTLA1; CTSGL1
- Gene ID
- 3002
- UniProt ID
- P10144
Related Resources
Allograft Rejection
Autoimmune Thyroid Disease
Graft-versus-Host Disease
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone Fv17"
See other products for "GZMB"
Select a product category from the dropdown menu below to view related products.
Please select product type
IgG Antibody Products
Fab Antibody Products
ScFv Antibody Products
Rabbit Monoclonal Antibody Products
Antibody Magnetic Beads
Non-Human Primate (NHP) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-424 | Recombinant Anti-human GZMB Antibody | ELISA, WB, IP, FuncS | IgG |
| MOB-1405MZ | Recombinant Mouse Anti-Human GZMB Antibody (clone HC22) | FC, IHC-Fr, IP | Mouse antibody |
| FAMAB-0137YC | Human Anti-GZMB Recombinant Antibody (clone Fv17) | ELISA, FC, WB, IP | Human IgG |
| VS-0224-XY56 | Human Anti-GZMB Recombinant Antibody (VS-0224-XY56) | ELISA | Human IgG1 |
| VS7-0425-WR7 | Mouse Anti-GZMB Recombinant Antibody (clone 2G12G7) | IHC | Mouse IgG2a |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for FAMAB-0137-YC-S(P). Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: IP, IF, FuncS, FC, Neut, ELISA, IHC
Application: WB, FuncS, IF, Neut, ELISA, FC, IP
Application: IF, IP, Neut, FuncS, ELISA, FC, WB
Application: ELISA, Neut, FuncS
Application: WB, Neut, FuncS
-3.png)
Application: ELISA, FC, Block, SPR
-2-1.png)
Application: ELISA
Application: ELISA, FC, WB, FuncS
Application: ELISA, FC
Application: FC, ADCC, CDC, Inhib
Application: ELISA, WB, FC, IHC, IP
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
