Recombinant Mouse Anti-HA Antibody Fab Fragment (H153-70A12) (CAT#: FAMAB-0254-YC-F(E))
Provided is a PR8-specific antibody, which binds to the PR8 HA (which contains Asp at residue 225).
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Specifications
- Immunogen
- PR8 virus
- Host Species
- Mouse
- Type
- Mouse Fab
- Specificity
- Influenza virus A PR8 HA
- Species Reactivity
- PR8 virus
- Clone
- H153-70A12
- Applications
- ELISA
Product Property
- Purity
- >95% as determined by analysis by SDS-PAGE
- Storage
- Store at -20°C for long-term storage. Avoid freeze/thaw cycles.
Target
- Alternative Names
- HA; Hemagglutinin
Related Resources
Wang, Lixue, et al. "Bioinspired engineering of fusogen and targeting moiety equipped nanovesicles." Nature Communications 14.1 (2023): 3366. https://doi.org/s41467-023-39181-2
This study focuses on the bioinspired engineering of fusogen and targeting moiety equipped nanovesicles (eFT-CNVs) to enhance drug delivery efficiency. The researchers developed eFT-CNVs by mechanically extruding genetically modified donor cells to produce high-yield and consistent nanovesicles. These engineered vesicles co-express a fusogen derived from the Sindbis virus and an anti-GPC3 single-chain variable fragment (scFv), enabling them to selectively bind to GPC3-overexpressing cancer cells and facilitate efficient cytosolic drug delivery through membrane fusion. The study demonstrated that eFT-CNVs significantly improve the treatment efficacy of drugs targeting cytosolic components, suggesting that these nanovesicles hold promise for advancing nanomedicine and precision medicine.
Creative Biolabs contributed to this research by providing the anti-HA antibody Fab fragment (Cat# FAMAB-0254-YC-F(E)). This antibody was essential for estimating the concentration of fusogen on eFT-CNVs, which was crucial for evaluating the efficiency of membrane fusion and drug delivery. By enabling precise quantification of fusogen molecules, the anti-HA antibody from Creative Biolabs supported the researchers in optimizing the design and functionality of the bioengineered nanovesicles, thereby facilitating the study's goal of enhancing targeted drug delivery systems.
More Infomation
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-203 | Recombinant Human Anti-IAV HA Antibody scFv Fragment (3.1) | WB, ELISA, FuncS | scFv |
| PSBL-204 | Recombinant Human Anti-IAV HA Antibody scFv Fragment (39.29) | Neut, FuncS | scFv |
| PSBL-205 | Recombinant Human Anti-IAV HA Antibody scFv Fragment (1957) | WB, Neut, FuncS | scFv |
| PSBL-206 | Recombinant Human Anti-IAV HA Antibody scFv Fragment (1F1) | WB, ELISA, FuncS | scFv |
| PSBL-207 | Recombinant Human Anti-IAV HA Antibody scFv Fragment (5J8) | WB, ELISA, FuncS | scFv |
Customer Reviews and Q&As
Customer Review
Q&As
Emily Hill
Ideal for HA Detection
Ideal for HA Detection
The Anti-HA Antibody Fab Fragment has delivered excellent results in our detection assays. The specificity and sensitivity for HA are top-notch, providing clear and accurate detection. This antibody has greatly improved our detection studies and made our experiments more reliable.
29.Nov,23
James Carter
High Specificity and Sensitivity
High Specificity and Sensitivity
We incorporated this antibody into our Western blot and immunoprecipitation assays, and it has been a great addition. The specificity and sensitivity for HA are outstanding, consistently detecting the target protein with high clarity. The reliable performance has made it an essential tool in our research.
26.Jul,22
Rachel Perez
Consistent and Reproducible
Consistent and Reproducible
This antibody has proven to be incredibly consistent in various assays, including flow cytometry and immunofluorescence. The high-quality, reproducible results and strong affinity for HA have significantly benefited our experiments, making it a staple in our lab. The consistent performance has greatly enhanced our data quality.
15.Jun,21
Cite This Product
To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# FAMAB-0254-YC-F(E), RRID: AB_3111324)
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