Mouse Anti-HGF Recombinant Antibody (VS3-FY2734)
CAT#: VS3-FY2734
The mouse anti-HGF recombinant monoclonal antibody has been developed to target HGF. The calculated molecular weight of the antigen is 83.1 kDa. It cross-reacts with human, mouse and rat. This monoclonal antibody is potential for conducting research on Angiogenesis-mediated disease. This monoclonal antibody can be used in Western Blot.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human rectum
Immunohistochemical staining of human rectum shows strong cytoplasmic and membranous positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/40360/ihc_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/40360/92262_B_8_5.jpg
Normal Tissue
Figure 3 Colon
Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/40360/92262_A_7_3.jpg
Normal Tissue
Figure 4 Kidney
Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/40360/92262_A_7_5.jpg
Normal Tissue
Figure 5 Testis
Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/40360/92262_A_5_6.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced.
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000019991-HGF
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Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Hepatocyte growth factor of human, mouse and rat origins
- Species Reactivity
- Human, Mouse, Rat
- Applications
- WB
- Conjugate
- Unconjugated, FITC
- MW
- The molecular weight of the target protein is approximately 83.1 kDa.
- Related Disease
- Angiogenesis-mediated disease
Product Property
- Clonality
- Monoclonal Antibody
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/100-1/1000
Target
- Alternative Names
- Hepatocyte Growth Factor; Hepatocyte Growth Factor (Hepapoietin A; Scatter Factor); Fibroblast-Derived Tumor Cytotoxic Factor; Lung Fibroblast-Derived Mitogen; Hepatopoietin-A; Scatter Factor; HPTA; SF
- Gene ID
- 3082
- UniProt ID
- P14210
- Sequence Similarities
- Belongs to the peptidase S1 family. Plasminogen subfamily.
- Post Translation Modifications
- The single-chain precursor undergoes proteolytic processing by TMPRSS13 resulting in an active two-chain form.
Glycosylation at Asn294, Asn402, Thr476, Asn566, and Asn653
Modification sites at PhosphoSitePlus
Glycosylation from Gly
Glycosylation from GlyGen 5 sites, 14 N-linked glycans (4 sites), 2 O-linked glycans (1 site)
- Protein Refseq
- XP_047276249.1; NP_000592.3; NP_001010931.1; NP_001010932.1; NP_001010933.1
- Function
- Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization (PubMed:20977675, 15167892).
Activates MAPK signaling following TMPRSS13 cleavage and activation (PubMed:20977675).
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1362z | Mouse Anti-HGF Recombinant Antibody (clone 23C2) | WB, ELISA, FuncS | Mouse IgG1 |
| HPAB-0713-FY | Mouse Anti-HGF Recombinant Antibody (clone AB012) | ELISA | Mouse IgG |
| HPAB-0821-FY | Mouse Anti-HGF Recombinant Antibody (clone S265109B10) | Neut, ELISA | Mouse IgG |
| HPAB-0378-YJ | Mouse Anti-HGF Recombinant Antibody (HPAB-0378-YJ) | ELISA, Neut, Inhib, FuncS | Mouse IgG2a, κ |
| HPAB-0380-YJ | Human Anti-HGF Recombinant Antibody (HPAB-0380-YJ) | ELISA, Neut, Inhib, FuncS | Humanized IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-080 | Human Anti-HGF Recombinant Antibody (TAB-080) | WB, ELISA, FC, IP, FuncS, IF, Neut | Human IgG2, κ |
| TAB-076CT | Anti-Human HGF/SF Recombinant Antibody (2C3) | ELISA, WB | Human antibody |
| TAB-076CT-S(P) | Anti-Human HGF/SF Recombinant Antibody scFv Fragment (2C3) | ELISA, WB | Human antibody |
| TAB-076CT-F(E) | Anti-Human HGF/SF Recombinant Antibody Fab Fragment (2C3) | ELISA, WB | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-749 | Anti-HGF Recombinant Antibody (TAB-749) | ELISA, FC, IP, FuncS, IF, Neut, WB | IgG1 - kappa |
| TAB-075CT | Human Anti-HGF Recombinant Antibody (TAB-075CT) | ELISA, Neut | Humanized antibody |
| TAB-075CT-S(P) | Human Anti-HGF Recombinant Antibody; scFv Fragment (TAB-075CT-S(P)) | ELISA, Neut | Humanized scFv |
| TAB-075CT-F(E) | Human Anti-HGF Recombinant Antibody; Fab Fragment (TAB-075CT-F(E)) | ELISA, Neut | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-078CT | Llama Anti-HGF Recombinant Single Domain Antibody (TAB-078CT) | Block | Llama VHH |
| HPAB-0993WJ | Recombinant Camelid Anti-HGF Single Domain Antibody (HPAB-0993WJ) | ELISA | Camelid VHH |
| HPAB-0994WJ | Recombinant Human Anti-HGF Antibody (HPAB-0994WJ) | ELISA | Humanized sdAb |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-900CQ | Mouse Anti-HGF Recombinant Antibody (clone 24612.111) | ELISA, WB, Neut | Mouse IgG1 |
| NEUT-901CQ | Mouse Anti-HGF Recombinant Antibody (clone 5D20) | WB, Neut | Mouse IgG1 |
| NEUT-902CQ | Mouse Anti-HGF Recombinant Antibody (clone CBL070) | Neut, WB | Mouse IgG1 |
| NEUT-903CQ | Mouse Anti-HGF Recombinant Antibody (clone CBL435) | WB, Neut | Mouse IgG1 |
| NEUT-904CQ | Mouse Anti-HGF Recombinant Antibody (clone CBL1017) | Neut | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1591 | Rabbit Anti-HGF Recombinant Antibody (clone DS1591AB) | ELISA | Rabbit IgG |
| MOR-4217 | Rabbit Anti-HGF Recombinant Antibody (clone SI296DS) | ELISA | Rabbit IgG |
| MOR-4585 | Rabbit Anti-HGF Recombinant Antibody (clone TH98DS) | WB, IF, ICC, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0651-CN-F(E) | Mouse Anti-HGF Recombinant Antibody; Fab Fragment (HPAB-0651-CN-F(E)) | ELISA, Neut | Mouse Fab |
| HPAB-0652-CN-F(E) | Mouse Anti-HGF Recombinant Antibody; Fab Fragment (HPAB-0652-CN-F(E)) | ELISA, Neut | Mouse Fab |
| HPAB-0653-CN-F(E) | Mouse Anti-HGF Recombinant Antibody; Fab Fragment (HPAB-0653-CN-F(E)) | ELISA, Neut | Mouse Fab |
| HPAB-0654-CN-F(E) | Mouse Anti-HGF Recombinant Antibody; Fab Fragment (HPAB-0654-CN-F(E)) | ELISA, Neut | Mouse Fab |
| HPAB-0655-CN-F(E) | Mouse Anti-HGF Recombinant Antibody; Fab Fragment (HPAB-0655-CN-F(E)) | ELISA, Neut | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-130 | Afuco™ Anti-HGF ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-130) | Neut, ELISA, IF, IP, FuncS, FC | ADCC enhanced antibody |
| AFC-TAB-749 | Afuco™ Anti-HGF ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-749) | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
| AFC-TAB-080 | Afuco™ Anti-HGF Recombinant Antibody (AFC-TAB-080), ADCC Enhanced | ELISA, FC, IP, FuncS, IF | Human IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0713-FY-F(E) | Mouse Anti-HGF Recombinant Antibody (clone AB012); scFv Fragment | ELISA | Mouse scFv |
| HPAB-0821-FY-F(E) | Mouse Anti-HGF Recombinant Antibody (clone S265109B10); scFv Fragment | Neut, ELISA | Mouse scFv |
| HPAB-0990WJ-S(P) | Human Anti-HGF Recombinant Antibody (clone 2.12.1); scFv Fragment | ELISA | Human scFv |
| HPAB-0991WJ-S(P) | Human Anti-HGF Recombinant Antibody (clone LRMR2B8); scFv Fragment | ELISA | Human scFv |
| HPAB-0994WJ-S(P) | Human Anti-HGF Recombinant Antibody (clone HGF13hum5); scFv Fragment | ELISA | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1015 | Anti-HGF Immunohistochemistry Kit | IHC | |
| VS-0525-XY3130 | Anti-Mouse HGF Immunohistochemistry Kit | IHC | |
| VS-0525-XY3129 | Anti-Human HGF Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY25 | Human Anti-HGF (clone BPC2015) scFv-Fc Chimera | ELISA, Inhib | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0625-YC141 | Recombinant Anti-HGF Eliminating Antibody, pH-Sensitive (VS-0625-YC141) | Antigen-Sweeping In Vivo. | Human IgG2 kappa |
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