Human Anti-HIV-1 gp41 Recombinant Antibody (clone 10-1487) (CAT#: MRO-4159CQ)

This product is a recombinant human anti-HIV-1 monoclonal antibody. 10-1487 specifically binds to gp41.


Specific Inquiry
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  • Published Data
  • Datasheet
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  • COA
FC

Figure 1 Protein microarray plots show the reactivity profile of blood anti-gp140 antibodies against human proteins.

Figure 1 Protein microarray plots show the reactivity profile of blood anti-gp140 antibodies against human proteins.

Each dot represents the average of duplicate array proteins. The diagonal lines indicate equal binding for reference and test antibodies.

Planchais, C., Kök, A., Kanyavuz, A., Lorin, V., Bruel, T., Guivel-Benhassine, F., ... & Lefrou, L. (2019). HIV-1 Envelope Recognition by Polyreactive and Cross-Reactive Intestinal B Cells. Cell reports, 27(2), 572-585.

ELISA

Figure 2 Representative ELISA graphs show the reactivity of blood anti-gp41 antibodies against overlapping peptides covering the extracellular portion of gp41 (gp41EC).

Figure 2 Representative ELISA graphs show the reactivity of blood anti-gp41 antibodies against overlapping peptides covering the extracellular portion of gp41 (gp41EC).

The sequences of the peptides recognized are indicated on the top.

Planchais, C., Kök, A., Kanyavuz, A., Lorin, V., Bruel, T., Guivel-Benhassine, F., ... & Lefrou, L. (2019). HIV-1 Envelope Recognition by Polyreactive and Cross-Reactive Intestinal B Cells. Cell reports, 27(2), 572-585.


Specifications

  • Host Species
  • Human
  • Type
  • Human IgG
  • Specificity
  • Recognizes HIV-1 gp41
  • Species Reactivity
  • HIV-1
  • Clone
  • 10-1487
  • Applications
  • ELISA, FC

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • The HIV-1 gp41 antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Flow Cytometry.

Target

  • Alternative Names
  • Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP41; gp41; HIV envelope

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone 10-1487"

See other products for "HIV-1 gp41"

MHC Tetramer for Virology

CAT Product Name Application Type
MHC-LC746 A*2402/HIV-1 gp41 (RYLKDQQLL) MHC Tetramer FCM

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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