Human Anti-HIV-1 gp41 Recombinant Antibody (clone 10-437) (CAT#: MRO-4160CQ)

This product is a recombinant human anti-HIV-1 monoclonal antibody. 10-437 specifically binds to gp41.

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  • Published Data
  • Datasheet
  • MSDS
  • COA
ELISA

Figure 1 Antibody binding to BaL gp140 and gp140(DMR/AAA) mutant protein by ELISA for the representative antigp120core antibodies.

Figure 1 Antibody binding to BaL gp140 and gp140(DMR/AAA) mutant protein by ELISA for the representative antigp120core antibodies.

All the experiments were performed at least in duplicate. Representative data are shown.

Mouquet, H., Klein, F., Scheid, J. F., Warncke, M., Pietzsch, J., Oliveira, T. Y., ... & Nussenzweig, M. C. (2011). Memory B cell antibodies to HIV-1 gp140 cloned from individuals infected with clade A and B viruses. PloS one, 6(9).

FC

Figure 2 Flow cytometry plots show the staining of patient PBMC.

Figure 2 Flow cytometry plots show the staining of patient PBMC.

The total number of memory B-cell antibodies is indicated in the center.

Mouquet, H., Klein, F., Scheid, J. F., Warncke, M., Pietzsch, J., Oliveira, T. Y., ... & Nussenzweig, M. C. (2011). Memory B cell antibodies to HIV-1 gp140 cloned from individuals infected with clade A and B viruses. PloS one, 6(9).


Specifications

  • Host Species
  • Human
  • Type
  • Human IgG
  • Specificity
  • Recognizes HIV-1 gp41
  • Species Reactivity
  • HIV-1
  • Clone
  • 10-437
  • Applications
  • ELISA, FC

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • The HIV-1 gp41 antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Flow Cytometry.

Target

  • Alternative Names
  • Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP41; gp41; HIV envelope

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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