Human Anti-HIV-1 gp41 Recombinant Antibody (clone Md-1 (MD-1, Md1)) (CAT#: MRO-4161CQ)

This product is a recombinant human anti-HIV-1 monoclonal antibody. Md-1 (MD-1, Md1) specifically binds to gp41.

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  • Published Data
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  • MSDS
  • COA
WB

Figure 1 Western blot detecting ADA.C1 Env glycoprotein with anti V3 mAb 447-52D and trimer-specific mAb Md-1.

Figure 1 Western blot detecting ADA.C1 Env glycoprotein with anti V3 mAb 447-52D and trimer-specific mAb Md-1.

CHO-neg corresponds to the supernatant of CHO cells transfected with empty vector and used as negative control for biopanning.

Trott, M., Weiß, S., Antoni, S., Koch, J., Von Briesen, H., Hust, M., & Dietrich, U. (2014). Functional characterization of two scFv-Fc antibodies from an HIV controller selected on soluble HIV-1 Env complexes: a neutralizing V3-and a trimer-specific gp41 antibody. PLoS One, 9(5).

ELISA

Figure 2 Characterization of soluble lectin purified ADA.C1 gp140 glycoproteins.

Figure 2 Characterization of soluble lectin purified ADA.C1 gp140 glycoproteins.

Binding of various mAbs directed against linear and conformational Env epitopes and HIV-positive sera to immobilized ADA.C1 determined by ELISA.

Trott, M., Weiß, S., Antoni, S., Koch, J., Von Briesen, H., Hust, M., & Dietrich, U. (2014). Functional characterization of two scFv-Fc antibodies from an HIV controller selected on soluble HIV-1 Env complexes: a neutralizing V3-and a trimer-specific gp41 antibody. PLoS One, 9(5).


Specifications

  • Host Species
  • Human
  • Type
  • Human IgG1, λ
  • Specificity
  • Recognizes HIV-1 gp41
  • Species Reactivity
  • HIV-1
  • Clone
  • Md-1 (MD-1, Md1)
  • Applications
  • ELISA, WB, IP

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • The HIV-1 gp41 antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Western blot, Immunoprecipitation.

Target

  • Alternative Names
  • Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP41; gp41; HIV envelope

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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