Human Anti-HIV-1 gp41 Recombinant Antibody (clone VRC34.05 (N123-VRC34.05)) (CAT#: MRO-4155CQ)

This product is a recombinant human anti-HIV-1 monoclonal antibody. VRC34.05 (N123-VRC34.05) specifically binds to gp41.


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ELISA

Figure 2 Binding of VRC34 lineage mAbs on BG505 SOSIP .664 gp140 trimer (right) in 
ELISA.

Figure 2 Binding of VRC34 lineage mAbs on BG505 SOSIP .664 gp140 trimer (right) in ELISA.

Broad neutralizers (VRC34.01-04) are highlighted in red and weak neutralizers
(VRC34.05-07) are highlighted in blue.

Kong, R., Xu, K., Zhou, T., Acharya, P., Lemmin, T., Liu, K., ... & Cale, E. M. (2016). Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody. Science, 352(6287), 828-833.


Specifications

  • Host Species
  • Human
  • Type
  • Human IgG
  • Specificity
  • Recognizes HIV-1 gp41
  • Species Reactivity
  • HIV-1
  • Clone
  • VRC34.05 (N123-VRC34.05)
  • Applications
  • ELISA, Neut

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • The HIV-1 gp41 antibody has been reported in applications of Enzyme-linked Immunosorbent Assay.

Target

  • Alternative Names
  • Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP41; gp41; HIV envelope

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

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MHC Tetramer for Virology

CAT Product Name Application Type
MHC-LC746 A*2402/HIV-1 gp41 (RYLKDQQLL) MHC Tetramer FCM

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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