Rabbit Anti-HNF4A Recombinant Antibody (VS13-YC540) (CAT#: VS13-YC540)
The Rabbit Anti-HNF4A Recombinant Antibody is specific for human HNF4A. HNF4A encodes a transcription factor regulating key hepatic genes, linked to type I diabetes mellitus due to its role in liver, kidney, and intestine development, with multiple transcript variants. The anti-HNF4A antibody can be used for Immunohistochemistry (1/100-1/200).
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line CACO-2
(Immunofluorescent staining of human cell line CACO-2 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4712/if_selected.jpg
(Immunofluorescent staining of human cell line CACO-2 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4712/if_selected.jpg
Figure 2 Duodenum
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4712/13034_A_9_2_val_selected.jpg
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4712/13034_A_9_2_val_selected.jpg
Figure 3 Stomach
(Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/19417/51797_A_3_1.jpg
(Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/19417/51797_A_3_1.jpg
Figure 4 Colon
(Enterocytes Staining: High Intensity: Strong Quantity:>75% Enterocytes - Goblet cells Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/19417/51797_A_9_3.jpg
(Enterocytes Staining: High Intensity: Strong Quantity:>75% Enterocytes - Goblet cells Staining: High Intensity: Strong Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/19417/51797_A_9_3.jpg
Figure 5 Liver
(Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/19417/51797_A_8_4.jpg
(Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/19417/51797_A_8_4.jpg
Figure 6 RNA cell line category: Group enriched (CACO-2, Hep G2, OE19)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000101076-HNF4A
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000101076-HNF4A
Specifications
- Immunogen
- Recombinant human HNF-4-alpha.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human HNF4A
- Species Reactivity
- Human
- Applications
- IHC-P
- Conjugate
- NONE
- Related Disease
- Cardiovascular Disease
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 50 mM Tris-Glycine (pH 7.4) containing 150 mM NaCl, 40% Glycerol and 0.05% BSA.
- Preservative
- 0.01% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Immunohistochemistry (IHC): 1/100-1/200
Target
- Alternative Names
- Hepatocyte Nuclear Factor 4 Alpha; Nuclear Receptor Subfamily 2 Group A Member 1; Transcription Factor HNF-4; Transcription Factor 14; TCF-14; TCF14; NR2A1; HNF4; Hepatocyte Nuclear Factor 4-Alpha; Hepatic Nuclear Factor 4 Alpha; HNF4alpha10/11/12;
- Gene ID
- 3172
- UniProt ID
- P41235
- Long Name
- Hepatocyte Nuclear Factor 4 Alpha
- Cellular Localization
- Nucleus
Recommended Products
Secondary Antibody
Isotype Control
Related Resources
cAMP Signaling Pathway
Type I Diabetes Mellitus
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "HNF4A"
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IgG Antibody Products
Rabbit Monoclonal Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2375MZ | Recombinant Mouse Anti-Human HNF4A Antibody | ICC/IF, WB | Mouse antibody |
| MRO-0757-CN | Rabbit Anti-HNF4A Recombinant Antibody (clone CBACN-280) | WB, IF, IHC, FC | Rabbit IgG |
| VS3-FY690 | Recombinant Mouse Anti-HNF4A Antibody (clone 8D12E3) | ELISA, IHC, FC | Mouse IgG2b |
| VS3-FY691 | Recombinant Rabbit Anti-Hnf4A Antibody (clone R01-7D7) | WB, IP, ChIP | Rabbit IgG |
| VS3-FY692 | Recombinant Rabbit Anti-Hnf4A Antibody (clone R02-7J6) | WB, IHC-Fr, IHC-P, ICC, IF | Rabbit IgG |
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