Mouse Anti-IgE Recombinant Antibody (clone 7A6) (CAT#: HPAB-AP103-YC)

Provided are anti-IgE antibodies that bind to the M1′ segment of a human IgE. The antibody can be used in treating and preventing IgE-mediated disorders, as well as kits comprising the anti-IgE antibodies.

Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Published Data
  • Datasheet
  • MSDS
  • COA
WB

Figure 1 Identification of schlstosomulum antigen reactlng wlth IgE.

Figure 1 Identification of schlstosomulum antigen reactlng wlth IgE.

Immune complexes were absorbed on protein A-Sepharoseand were then analyzed.

Verwaerde, C., Joseph, M., Capron, M., Pierce, R. J., Damonneville, M., Velge, F., ... & Capron, A. (1987). Functional properties of a rat monoclonal IgE antibody specific for Schistosoma mansoni. The Journal of Immunology, 138(12), 4441-4446.

FuncS

Figure 2 Killing of S. mansoni schistosomula by B48-14 IgE In the presence of various effector cells.

Figure 2 Killing of S. mansoni schistosomula by B48-14 IgE In the presence of various effector cells.

Schistosomula were incubated with effector cells.

Verwaerde, C., Joseph, M., Capron, M., Pierce, R. J., Damonneville, M., Velge, F., ... & Capron, A. (1987). Functional properties of a rat monoclonal IgE antibody specific for Schistosoma mansoni. The Journal of Immunology, 138(12), 4441-4446.

ELISA

Figure 3 Detection of anti-DNP IgE antibody by ELISA.

Figure 3 Detection of anti-DNP IgE antibody by ELISA.

The ordinate indicates the optical density (OD: 492 nm) of ELISA readings after subtraction of the background.

Verwaerde, C., Joseph, M., Capron, M., Pierce, R. J., Damonneville, M., Velge, F., ... & Capron, A. (1987). Functional properties of a rat monoclonal IgE antibody specific for Schistosoma mansoni. The Journal of Immunology, 138(12), 4441-4446.


Specifications

  • Host Species
  • Mouse
  • Type
  • Mouse IgG
  • Specificity
  • Human IgE
  • Species Reactivity
  • Human
  • Clone
  • 7A6
  • Applications
  • WB, FuncS, ELISA

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • The IgE antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Western Blot, Functional Assay.

Target

  • Alternative Names
  • Immunoglobulin E

Related Resources

  • Related Diseases

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone 7A6"

See other products for "IgE"

Select a product category from the dropdown menu below to view related products.
Please select product type
Humanized Antibody Products Single Domain Antibody Products Fab Glycosylation Antibody Products Fc Glycosylation Antibody Products Low- or Non-fucosylated Oligosaccharide Antibody Products ScFv Antibody Products Fab Antibody Products IgG Antibody Products

Customer Reviews and Q&As

Submit a review or a question

There are currently no Customer reviews or questions for HPAB-AP103-YC. Click the button above to contact us or submit your feedback about this product.

Popular products with customers


For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

  • 0
  • 0
Cart
    Go to compare

    Go to compare