Provided are anti-IgE antibodies that bind to the M1′ segment of a human IgE. The antibody can be used in treating and preventing IgE-mediated disorders, as well as kits comprising the anti-IgE antibodies.
Figure 1 Identification of schlstosomulum antigen reactlng wlth IgE.
Immune complexes were absorbed on protein A-Sepharoseand were then analyzed.
Verwaerde, C., Joseph, M., Capron, M., Pierce, R. J., Damonneville, M., Velge, F., ... & Capron, A. (1987). Functional properties of a rat monoclonal IgE antibody specific for Schistosoma mansoni. The Journal of Immunology, 138(12), 4441-4446.
Figure 2 Killing of S. mansoni schistosomula by B48-14 IgE In the presence of various effector cells.
Schistosomula were incubated with effector cells.
Verwaerde, C., Joseph, M., Capron, M., Pierce, R. J., Damonneville, M., Velge, F., ... & Capron, A. (1987). Functional properties of a rat monoclonal IgE antibody specific for Schistosoma mansoni. The Journal of Immunology, 138(12), 4441-4446.
Figure 3 Detection of anti-DNP IgE antibody by ELISA.
The ordinate indicates the optical density (OD: 492 nm) of ELISA readings after subtraction of the background.
Verwaerde, C., Joseph, M., Capron, M., Pierce, R. J., Damonneville, M., Velge, F., ... & Capron, A. (1987). Functional properties of a rat monoclonal IgE antibody specific for Schistosoma mansoni. The Journal of Immunology, 138(12), 4441-4446.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
TAB-034ZJ | Anti-Human IgE Recombinant Antibody (CMAB007) | ELISA | Humanized antibody |
TAB-049ZJ | Anti-Human IgE Recombinant Antibody (IGE009) | ELISA, Inhib, FC | Humanized antibody |
TAB-050ZJ | Anti-Human IgE Recombinant Antibody (IGE026) | ELISA, Inhib, FC | Humanized antibody |
TAB-034ZJ-F(E) | Anti-Human IgE Recombinant Antibody Fab Fragment (CMAB007) | ELISA | Humanized antibody |
TAB-049ZJ-F(E) | Anti-Human IgE Recombinant Antibody Fab Fragment (IGE009) | ELISA, Inhib, FC | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-095ZJ | Anti-Human IgE Therapeutic Single Domain Antibody (39D11) | ELISA, Inhib, FC | Single domain antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-009LC | Recombinant Anti-Human IgE Antibody (Fab glycosylation/Fc glycosylation) | ELISA, IP | Human antibody |
Gly-010LC | Recombinant Anti-Human IgE Antibody (Fab glycosylation/Fc glycosylation) | ELISA, IP | Human antibody |
Gly-011LC | Recombinant Anti-Human IgE Antibody (Fab glycosylation/Fc glycosylation) | ELISA, IP | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-009LC-1 | Recombinant Anti-Human IgE Antibody (Fab glycosylation/Fc glycosylation) | ELISA, IP | Human antibody |
Gly-010LC-1 | Recombinant Anti-Human IgE Antibody (Fab glycosylation/Fc glycosylation) | ELISA, IP | Human antibody |
Gly-011LC-1 | Recombinant Anti-Human IgE Antibody (Fab glycosylation/Fc glycosylation) | ELISA, IP | Human antibody |
Gly-156LC | Recombinant Anti-Human IgE Antibody (Fc glycosylation/Non fucosylated) | ELISA | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-156LC-1 | Recombinant Anti-Human IgE Antibody (Fc glycosylation/Non fucosylated) | ELISA | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0126-FY-F(E) | Human Anti-IgE Recombinant Antibody (clone 2E19); Fab Fragment | FC | Humanized Fab |
HPAB-0208CQ-F(E) | Mouse Anti-IgE Recombinant Antibody (clone TES-C21); Fab Fragment | ELISA, Block | Mouse Fab |
HPAB-0209CQ-F(E) | Human Anti-IgE Recombinant Antibody (clone huTES-C21); Fab Fragment | ELISA, Block | Humanized Fab |
HPAB-N0143-YC-F(E) | Human Anti-IgE Recombinant Antibody (clone hu4F11-12); Fab Fragment | ELISA, Inhib | Humanized Fab |
HPAB-0283-YJ-F(E) | Mouse Anti-IgE Recombinant Antibody; Fab Fragment (HPAB-0283-YJ-F(E)) | ELISA, Enzymatic activity | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0208CQ | Mouse Anti-IgE Recombinant Antibody (clone TES-C21) | ELISA, Block, FuncS | Mouse IgG1 |
HPAB-0209CQ | Human Anti-IgE Recombinant Antibody (clone huTES-C21) | ELISA, Block | Humanized IgG1 |
HPAB-N0143-YC | Human Anti-IgE Recombinant Antibody (clone hu4F11-12) | ELISA, Inhib | Humanized IgG1, κ |
HPAB-1281WJ | Canine Anti-IgE Recombinant Antibody (clone c15A.2) | Inhib, ELISA | Chimeric (mouse/canine) IgG |
FAMAB-1380CQ | Rat Anti-IgE Recombinant Antibody (clone R1E4) | FC, FuncS, ELISA | Rat IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0209CQ-S(P) | Human Anti-IgE Recombinant Antibody (clone huTES-C21); scFv Fragment | ELISA, Block | Humanized scFv |
HPAB-0043-WJ-S(P) | Mouse Anti-IgE Recombinant Antibody; scFv Fragment (HPAB-0043-WJ-S(P)) | ELISA, WB | Mouse scFv |
HPAB-0283-YJ-S(P) | Mouse Anti-IgE Recombinant Antibody; scFv Fragment (HPAB-0283-YJ-S(P)) | ELISA, Enzymatic activity | Mouse scFv |
HPAB-1195-FY-F(E) | Human Anti-IgE Recombinant Antibody; Fab Fragment (HPAB-1195-FY-F(E)) | ELISA | Human Fab |
HPAB-1196-FY-F(E) | Human Anti-IgE Recombinant Antibody; Fab Fragment (HPAB-1196-FY-F(E)) | ELISA | Human Fab |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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