Mouse Anti-IgE Recombinant Antibody (clone 7A6) (CAT#: HPAB-AP103-YC)

Provided are anti-IgE antibodies that bind to the M1′ segment of a human IgE. The antibody can be used in treating and preventing IgE-mediated disorders, as well as kits comprising the anti-IgE antibodies.


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  • Published Data
  • Datasheet
  • MSDS
  • COA
WB

Figure 1 Identification of schlstosomulum antigen reactlng wlth IgE.

Figure 1 Identification of schlstosomulum antigen reactlng wlth IgE.

Immune complexes were absorbed on protein A-Sepharoseand were then analyzed.

Verwaerde, C., Joseph, M., Capron, M., Pierce, R. J., Damonneville, M., Velge, F., ... & Capron, A. (1987). Functional properties of a rat monoclonal IgE antibody specific for Schistosoma mansoni. The Journal of Immunology, 138(12), 4441-4446.

FuncS

Figure 2 Killing of S. mansoni schistosomula by B48-14 IgE In the presence of various effector cells.

Figure 2 Killing of S. mansoni schistosomula by B48-14 IgE In the presence of various effector cells.

Schistosomula were incubated with effector cells.

Verwaerde, C., Joseph, M., Capron, M., Pierce, R. J., Damonneville, M., Velge, F., ... & Capron, A. (1987). Functional properties of a rat monoclonal IgE antibody specific for Schistosoma mansoni. The Journal of Immunology, 138(12), 4441-4446.

ELISA

Figure 3 Detection of anti-DNP IgE antibody by ELISA.

Figure 3 Detection of anti-DNP IgE antibody by ELISA.

The ordinate indicates the optical density (OD: 492 nm) of ELISA readings after subtraction of the background.

Verwaerde, C., Joseph, M., Capron, M., Pierce, R. J., Damonneville, M., Velge, F., ... & Capron, A. (1987). Functional properties of a rat monoclonal IgE antibody specific for Schistosoma mansoni. The Journal of Immunology, 138(12), 4441-4446.


Specifications

  • Host Species
  • Mouse
  • Type
  • Mouse IgG
  • Specificity
  • Human IgE
  • Species Reactivity
  • Human
  • Clone
  • 7A6
  • Applications
  • WB, FuncS, ELISA

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • The IgE antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Western Blot, Functional Assay.

Target

  • Alternative Names
  • Immunoglobulin E

Related Resources

  • Related Diseases

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone 7A6"

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Humanized Antibody

CAT Product Name Application Type
TAB-034ZJ Anti-Human IgE Recombinant Antibody (CMAB007) ELISA Humanized antibody
TAB-049ZJ Anti-Human IgE Recombinant Antibody (IGE009) ELISA, Inhib, FC Humanized antibody
TAB-050ZJ Anti-Human IgE Recombinant Antibody (IGE026) ELISA, Inhib, FC Humanized antibody
TAB-034ZJ-F(E) Anti-Human IgE Recombinant Antibody Fab Fragment (CMAB007) ELISA Humanized antibody
TAB-049ZJ-F(E) Anti-Human IgE Recombinant Antibody Fab Fragment (IGE009) ELISA, Inhib, FC Humanized antibody

Single-domain Antibody

CAT Product Name Application Type
TAB-095ZJ Anti-Human IgE Therapeutic Single Domain Antibody (39D11) ELISA, Inhib, FC Single domain antibody

Low- or Non-fucosylated Oligosaccharide

CAT Product Name Application Type
Gly-156LC-1 Recombinant Anti-Human IgE Antibody (Fc glycosylation/Non fucosylated) ELISA Humanized antibody

Recombinant Antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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