Mouse Anti-IgE Recombinant Antibody (clone 7A6) (CAT#: HPAB-AP103-YC)
Provided are anti-IgE antibodies that bind to the M1′ segment of a human IgE. The antibody can be used in treating and preventing IgE-mediated disorders, as well as kits comprising the anti-IgE antibodies.
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
Figure 1 Identification of schlstosomulum antigen reactlng wlth IgE.
Immune complexes were absorbed on protein A-Sepharoseand were then analyzed.
Verwaerde, C., Joseph, M., Capron, M., Pierce, R. J., Damonneville, M., Velge, F., ... & Capron, A. (1987). Functional properties of a rat monoclonal IgE antibody specific for Schistosoma mansoni. The Journal of Immunology, 138(12), 4441-4446.
Figure 2 Killing of S. mansoni schistosomula by B48-14 IgE In the presence of various effector cells.
Schistosomula were incubated with effector cells.
Verwaerde, C., Joseph, M., Capron, M., Pierce, R. J., Damonneville, M., Velge, F., ... & Capron, A. (1987). Functional properties of a rat monoclonal IgE antibody specific for Schistosoma mansoni. The Journal of Immunology, 138(12), 4441-4446.
Figure 3 Detection of anti-DNP IgE antibody by ELISA.
The ordinate indicates the optical density (OD: 492 nm) of ELISA readings after subtraction of the background.
Verwaerde, C., Joseph, M., Capron, M., Pierce, R. J., Damonneville, M., Velge, F., ... & Capron, A. (1987). Functional properties of a rat monoclonal IgE antibody specific for Schistosoma mansoni. The Journal of Immunology, 138(12), 4441-4446.
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human IgE
- Species Reactivity
- Human
- Clone
- 7A6
- Applications
- WB, FuncS, ELISA
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The IgE antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Western Blot, Functional Assay.
Target
- Alternative Names
- Immunoglobulin E
Related Resources
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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