Human Anti-IgE Recombinant Antibody (clone e25) (CAT#: HPAB-AP682-YC)
Provided is a immunoglobulin that binds IgE with high affinity. The antibody is capable of inhibiting cells that express membrane-anchored IgE. Also, the antibody is useful for treating IgE-mediated disorders, including allergies and asthma.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Funcs
Figure 1 Results of Efforts to Taper the Dose of Corticosteroids.
Seventy-eight percent of the subjects in the high-dose group (P=0.04) and 57 percent of those in the low-dose group (P=0.23) had a reduction in the dose of oral corticosteroids of at least 50 percent, as compared with 33 percent of subjects in the placebo group.
Milgrom, H., Fick Jr, R. B., Su, J. Q., Reimann, J. D., Bush, R. K., Watrous, M. L., & Metzger, W. J. (1999). Treatment of allergic asthma with monoclonal anti-IgE antibody. New England Journal of Medicine, 341(26), 1966-1973.
Specifications
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized IgG
- Specificity
- Human IgE
- Species Reactivity
- Human
- Clone
- e25
- Applications
- FuncS, ELISA, Inhib
- Related Disease
- Allergies and Asthma
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The IgE antibody has been reported in applications of Functional Assay, Enzyme-linked Immunosorbent Assay, Inhibition.
Target
- Alternative Names
- Immunoglobulin E
Related Resources
Asthma
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-034ZJ-S(P) | Anti-Human IgE Recombinant Antibody scFv Fragment (CMAB007) | ELISA | Humanized antibody |
| TAB-049ZJ-S(P) | Anti-Human IgE Recombinant Antibody scFv Fragment (IGE009) | ELISA, Inhib, FC | Humanized antibody |
| TAB-050ZJ-S(P) | Anti-Human IgE Recombinant Antibody scFv Fragment (IGE026) | ELISA, Inhib, FC | Humanized antibody |
| TAB-049ZJ-F(E) | Anti-Human IgE Recombinant Antibody Fab Fragment (IGE009) | ELISA, Inhib, FC | Humanized antibody |
| TAB-050ZJ-F(E) | Anti-Human IgE Recombinant Antibody Fab Fragment (IGE026) | ELISA, Inhib, FC | Humanized antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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