Mouse Anti-IL18R1 Recombinant Antibody (clone 117-10C); scFv Fragment
CAT#: FAMAB-0315JF-S(P)
Recombinant monoclonal antibody specially binds to human IL-18R1. 117-10C is a mouse monoclonal antibody that can be useful in neutralizing the cytokine in human conditions associated with high production of IL-18.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to mitochondria.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7615/if_selected.jpg
Normal Tissue
Figure 2 IHC staining of human stomach
Immunohistochemical staining of human stomach shows strong cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7615/ihc_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7615/28557_B_8_5.jpg
Normal Tissue
Figure 4 Colon
Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7615/28557_A_9_3.jpg
Normal Tissue
Figure 5 Liver
Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7615/28557_A_7_4.jpg
Normal Tissue
Figure 6 Kidney
Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7615/28557_A_7_5.jpg
Normal Tissue
Figure 7 Testis
Elongated or late spermatids Staining: Medium Intensity: Moderate Quantity:>75% Leydig cells Staining: High Intensity: Strong Quantity:>75% Pachytene spermatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Preleptotene spermatocytes Staining: Low Intensity: Moderate Quantity: <25% Spermatogonia cells Staining: High Intensity: Strong
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7615/28557_A_6_6.jpg
Normal Tissue
Figure 8 Appendix
Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Lymphoid tissue Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7615/28557_A_3_2.jpg
Normal Tissue
Figure 9 Lymph node
Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/7615/28557_A_9_8.jpg
RNA Expression
Figure 10 RNA cell line category: Cell line enhanced (HDLM-2, HHSteC, U-937)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000115604-IL18R1
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Specifications
- Immunogen
- Cells of the Hodgkin's disease-derived cell line L428
- Host Species
- Mouse
- Type
- Mouse scFv
- Specificity
- Human IL-18R1
- Species Reactivity
- Human
- Clone
- 117-10C
- Applications
- ELISA, FuncS
- Related Disease
- Autoimmune diseases
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Related Signaling Pathways
TNF Signaling Pathway
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone 117-10C"
- CAT
- Product Name
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1369z | Mouse Anti-IL18R1 Recombinant Antibody (clone 22B12) | ELISA, WB, IP, FuncS | Mouse IgG1 |
| MOB-0235CT | Recombinant Mouse anti-Human IL18R1 Monoclonal antibody (80736.222) | I-ELISA, Neut, WB | |
| HPAB-658-FY | Mouse Anti-IL18R1 Recombinant Antibody (HPAB-658-FY) | FC | Mouse IgG |
| HPAB-659-FY | Mouse Anti-IL18R1 Recombinant Antibody (HPAB-659-FY) | FC | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G042E | IL-18-PE immunotoxin | Cytotoxicity assay, Function study | |
| AGTO-G042D | IL-18-DT immunotoxin | Cytotoxicity assay, Function study |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-207CT | Mouse Anti-IL18R1 Recombinant Antibody (TAB-207CT) | Neut, ELISA, Block | Mouse IgG |
| TAB-207CT-S(P) | Mouse Anti-IL18R1 Recombinant Antibody; scFv Fragment (TAB-207CT-S(P)) | Neut, ELISA, Block | Mouse scFv |
| TAB-208CT-S(P) | Mouse Anti-IL18R1 Recombinant Antibody; scFv Fragment (TAB-208CT-S(P)) | Neut, ELISA, Block | Mouse scFv |
| TAB-209CT-S(P) | Mouse Anti-IL18R1 Recombinant Antibody; scFv Fragment (TAB-209CT-S(P)) | FC, ELISA, Ibhibition | Mouse scFv |
| TAB-210CT-S(P) | Mouse Anti-IL18R1 Recombinant Antibody; scFv Fragment (TAB-210CT-S(P)) | FC, ELISA, Ibhibition | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-211CT | Human Anti-IL18R1 Recombinant Antibody (TAB-211CT) | FC, ELISA, Ibhibition | Humanized antibody |
| TAB-211CT-S(P) | Human Anti-IL18R1 Recombinant Antibody; scFv Fragment (TAB-211CT-S(P)) | FC, ELISA, Ibhibition | Humanized scFv |
| TAB-211CT-F(E) | Human Anti-IL18R1 Recombinant Antibody; Fab Fragment (TAB-211CT-F(E)) | FC, ELISA, Ibhibition | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1247CQ | Mouse Anti-IL18R1 Recombinant Antibody (clone CBL489) | FC, IHC, CyTOF, ICC, Neut | Mouse IgG1 |
| NEUT-1248CQ | Mouse Anti-IL18R1 Recombinant Antibody (clone 70625.111) | I-ELISA, Neut, WB | Mouse IgG1 |
| NEUT-1249CQ | Mouse Anti-IL18R1 Recombinant Antibody (clone 8H22) | IHC, Neut, WB | Mouse IgG1 |
| NEUT-1250CQ | Rat Anti-Il18r1 Recombinant Antibody (clone CBL522) | WB, Neut | Rat IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4250 | Rabbit Anti-Il18r1 Recombinant Antibody (clone SI329DS) | ELISA | Rabbit IgG |
| MOR-4251 | Rabbit Anti-IL18R1 Recombinant Antibody (clone SI330DS) | ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-658-FY-S(P) | Mouse Anti-IL18R1 Recombinant Antibody; scFv Fragment (HPAB-658-FY-S(P)) | Inhib, FC, ELISA | Mouse scFv |
| HPAB-659-FY-S(P) | Mouse Anti-IL18R1 Recombinant Antibody; scFv Fragment (HPAB-659-FY-S(P)) | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-658-FY-F(E) | Mouse Anti-IL18R1 Recombinant Antibody; Fab Fragment (HPAB-658-FY-F(E)) | Inhib, FC, ELISA | Mouse Fab |
| HPAB-659-FY-F(E) | Mouse Anti-IL18R1 Recombinant Antibody; Fab Fragment (HPAB-659-FY-F(E)) | ELISA | Mouse Fab |
| FAMAB-0315JF-F(E) | Mouse Anti-IL18R1 Recombinant Antibody (clone 117-10C); Fab Fragment | ELISA, FuncS | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0315JF | Mouse Anti-IL18R1 Recombinant Antibody (clone 117-10C) | ELISA, FuncS | Mouse IgM, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY4 | Mouse Anti-IL18R1 scFv-Fc Chimera (VS-0425-FY4) | Inhib, ELISA | Mouse IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC211 | Recombinant Anti-IL18R1 Vesicular Antibody, EV Displayed (VS-0425-YC211) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3501 | Anti-IL18R1 Immunohistochemistry Kit | IHC |
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