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IL18R1
Loading...Anti-IL18R1 Products
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB, IP, FuncS
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- Mouse Anti-Il18r1 Antibody, mRNA (AGTO-G042D-mRNA)
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- Species Reactivity: Mouse
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- Human Anti-IL18R1 Antibody, mRNA (TAB-406CL-mRNA)
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- Species Reactivity: Human
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- Mouse Anti-IL18R1 Recombinant Antibody (clone 117-10C) (FAMAB-0315JF)
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- Species Reactivity: Human
- Type: Mouse IgM, κ
- Application: ELISA, FuncS
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- Rat Anti-Il18r1 Recombinant Antibody (clone CBL522) (NEUT-1250CQ)
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- Species Reactivity: Mouse
- Type: Rat IgG2a
- Application: WB, Neut
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- Mouse Anti-IL18R1 Recombinant Antibody (HPAB-658-FY) (HPAB-658-FY)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: FC
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- Mouse Anti-IL18R1 Recombinant Antibody (HPAB-659-FY) (HPAB-659-FY)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: FC
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- Mouse Anti-IL18R1 Recombinant Antibody (clone CBL489) (NEUT-1247CQ)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: FC, IHC, CyTOF, ICC, Neut
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- Mouse Anti-IL18R1 Recombinant Antibody (clone 70625.111) (NEUT-1248CQ)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: I-ELISA, Neut, WB
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- Mouse Anti-IL18R1 Recombinant Antibody (clone 8H22) (NEUT-1249CQ)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: IHC, Neut, WB
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- Species Reactivity: Human, Monkey
- Type: Humanized antibody
- Application: FC, ELISA, Ibhibition
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- Mouse Anti-IL18R1 Recombinant Antibody; scFv Fragment (HPAB-658-FY-S(P)) (HPAB-658-FY-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: Inhib, FC, ELISA
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- Mouse Anti-IL18R1 Recombinant Antibody (clone 117-10C); Fab Fragment (FAMAB-0315JF-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, FuncS
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- Mouse Anti-IL18R1 Recombinant Antibody (clone 117-10C); scFv Fragment (FAMAB-0315JF-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, FuncS
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- Mouse Anti-IL18R1 Recombinant Antibody; scFv Fragment (HPAB-659-FY-S(P)) (HPAB-659-FY-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
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- Mouse Anti-IL18R1 Recombinant Antibody; Fab Fragment (HPAB-658-FY-F(E)) (HPAB-658-FY-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: Inhib, FC, ELISA
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- Mouse Anti-IL18R1 Recombinant Antibody; Fab Fragment (HPAB-659-FY-F(E)) (HPAB-659-FY-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
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- IL-18-PE immunotoxin (AGTO-G042E)
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- Species Reactivity: Mouse
- Application: Cytotoxicity assay, Function study
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- IL-18-DT immunotoxin (AGTO-G042D)
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- Species Reactivity: Mouse
- Application: Cytotoxicity assay, Function study
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- Anti-Human IL18R1 Recombinant Antibody (TAB-406CL)
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- Species Reactivity: Human
- Type: Antibody
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- Mouse Anti-IL18R1 scFv-Fc Chimera (VS-0425-FY4) (VS-0425-FY4)
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- Species Reactivity: Human
- Type: Mouse IgG1, scFv-Fc
- Application: Inhib, ELISA
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- Species Reactivity: Human, Monkey
- Target: IL18R1
- Host Animal: Human
- Application: ELISA, FC, Cell-uptake
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- Anti-IL18R1 Immunohistochemistry Kit (VS-0525-XY3501)
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- Species Reactivity: Human
- Target: IL18R1
- Application: IHC
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More Infomation
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For Research Use Only. Not For Clinical Use.
Background
The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]
Protein class
CD markers, Enzymes, Plasma proteins
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (granulocytes, dendritic cells, NK-cells, Langerhans cells, T-cells)
Immune cell specificity
Immune cell enhanced (NK-cell)
Cell line specificity
Cell line enhanced (HDLM-2, HHSteC, U-937)
Interaction
Forms a ternary complex with IL18 and IL18RAP (PubMed:14528293, PubMed:25500532). Within this complex, IL18R1 is involved in ligand-binding and IL18RAP in signaling leading to NF-kappa-B and JNK activation (Probable). Interacts with SLC12A3 in peritoneal macrophages; this interaction is increased by IL18 treatment (By similarity).
Molecular function
Hydrolase, Receptor
More Types Infomation
Related Signaling Pathways
TNF Signaling Pathway