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IL18R1
Anti-IL18R1 Recombinant Antibody Products
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, WB, IP, FuncS
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- Mouse Anti-Il18r1 Antibody, mRNA (AGTO-G042D-mRNA)
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- Species Reactivity: Mouse
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- Human Anti-IL18R1 Antibody, mRNA (TAB-406CL-mRNA)
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- Species Reactivity: Human
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- Mouse Anti-IL18R1 Recombinant Antibody (clone 117-10C) (FAMAB-0315JF)
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- Species Reactivity: Human
- Type: Mouse IgM, κ
- Application: ELISA, FuncS
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- Mouse Anti-IL18R1 Recombinant Antibody (HPAB-658-FY) (HPAB-658-FY)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: FC
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- Mouse Anti-IL18R1 Recombinant Antibody (HPAB-659-FY) (HPAB-659-FY)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: FC
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- Mouse Anti-IL18R1 Recombinant Antibody (clone CBL489) (NEUT-1247CQ)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: FC, IHC, CyTOF, ICC, Neut
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- Mouse Anti-IL18R1 Recombinant Antibody (clone 70625.111) (NEUT-1248CQ)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: I-ELISA, Neut, WB
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- Mouse Anti-IL18R1 Recombinant Antibody (clone 8H22) (NEUT-1249CQ)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: IHC, Neut, WB
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- Rat Anti-Il18r1 Recombinant Antibody (clone CBL522) (NEUT-1250CQ)
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- Species Reactivity: Mouse
- Type: Rat IgG2a
- Application: WB, Neut
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- Species Reactivity: Human, Monkey
- Type: Humanized antibody
- Application: FC, ELISA, Ibhibition
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- Mouse Anti-IL18R1 Recombinant Antibody; scFv Fragment (HPAB-658-FY-S(P)) (HPAB-658-FY-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: Inhib, FC, ELISA
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- Mouse Anti-IL18R1 Recombinant Antibody (clone 117-10C); Fab Fragment (FAMAB-0315JF-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, FuncS
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- Mouse Anti-IL18R1 Recombinant Antibody (clone 117-10C); scFv Fragment (FAMAB-0315JF-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, FuncS
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- Mouse Anti-IL18R1 Recombinant Antibody; scFv Fragment (HPAB-659-FY-S(P)) (HPAB-659-FY-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
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- Mouse Anti-IL18R1 Recombinant Antibody; Fab Fragment (HPAB-658-FY-F(E)) (HPAB-658-FY-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: Inhib, FC, ELISA
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- Mouse Anti-IL18R1 Recombinant Antibody; Fab Fragment (HPAB-659-FY-F(E)) (HPAB-659-FY-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
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- IL-18-PE immunotoxin (AGTO-G042E)
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- Species Reactivity: Mouse
- Application: Cytotoxicity assay, Function study
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- IL-18-DT immunotoxin (AGTO-G042D)
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- Species Reactivity: Mouse
- Application: Cytotoxicity assay, Function study
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- Anti-Human IL18R1 Recombinant Antibody (TAB-406CL)
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- Species Reactivity: Human
- Type: Antibody
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Protein class
CD markers, Enzymes, Plasma proteins
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (granulocytes, dendritic cells, NK-cells, Langerhans cells, T-cells)
Immune cell specificity
Immune cell enhanced (NK-cell)
Cell line specificity
Cell line enhanced (HDLM-2, HHSteC, U-937)
Interaction
Forms a ternary complex with IL18 and IL18RAP (PubMed:14528293, PubMed:25500532). Within this complex, IL18R1 is involved in ligand-binding and IL18RAP in signaling leading to NF-kappa-B and JNK activation (Probable). Interacts with SLC12A3 in peritoneal macrophages; this interaction is increased by IL18 treatment (By similarity).
Molecular function
Hydrolase, Receptor
More Types Infomation
Related Signaling Pathways
TNF Signaling Pathway