What is the antibody clone encoded by this mRNA?

This mRNA product encodes the Human antibody clone Mepolizumab. It is designed to express an antibody that targets Interleukin 5 (IL5), a key cytokine in eosinophil activation.

What are the storage requirements for this mRNA product?

This mRNA product should be stored at -20°C. It is important to handle it carefully to maintain stability and prevent degradation of the RNA sequences encoding the heavy and light chains.

Human Anti-IL5 Antibody (clone Mepolizumab), mRNA

CAT#: TAB-031-mRNA

This mRNA encodes a Human antibody against IL5. It contains two mRNAs that encode for the heavy and light chains of the antibody.

Gene Expression

RNA Expression Figure 1 RNA cell line category: Cell line enhanced (Hep G2, TIME)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000113525-IL5

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Specifications

Immunogen
Recombinant human IL5.

Host Species
Human

Specificity
Human IL5

Species Reactivity
Human

Clone
Mepolizumab

Related Disease
Asthma

Product Property

Purity
>95%

Storage
Store at -20°C.

Target

Alternative Names
Mepolizumab;bosatria;196078-29-2;SB-240563;IL5;interleukin 5 (colony-stimulating factor, eosinophil);interleukin-5;B cell differentiation factor I;EDF;eosinophil differentiation factor;IL 5;interleukin 5;T cell replacing factor;TRF;T-cell replacing factor

Gene ID
3567

UniProt ID
P05113

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Breast cancer biomarkers at key points during disease progression

Innovative mRNA Format

Using mRNA to generate the anti-IL5 antibody directly in our cellular models was a novel approach for us. This product containing sequences for both heavy and light chains worked beautifully. It allowed us to study the effects of the antibody in a more dynamic system.

Consistent Antibody Production

The stability of this mRNA product is commendable. We stored it at -20°C and saw no degradation over time. The encoded human antibody against IL5 was expressed efficiently, enabling us to proceed with our downstream functional analysis regarding eosinophil activation pathways.

Q&As

What is the antibody clone encoded by this mRNA?

A: This mRNA product encodes the Human antibody clone Mepolizumab. It is designed to express an antibody that targets Interleukin 5 (IL5), a key cytokine in eosinophil activation.
What are the storage requirements for this mRNA product?

A: This mRNA product should be stored at -20°C. It is important to handle it carefully to maintain stability and prevent degradation of the RNA sequences encoding the heavy and light chains.

View the frequently asked questions answered by Creative Biolabs Support.

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Related Diseases

Asthma

Inflammatory Bowel Diseases

Autoimmune Thyroid Disease

Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - TAB-031-mRNA.pdf

MSDS

MSDS - TAB-031-mRNA.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number:

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