Mouse Anti-IRF6 Recombinant Antibody (VS-1225-XY142)
CAT#: VS-1225-XY142
It serves as a key research tool targeting IRF6, supporting cellular and molecular experiments. This antibody performs consistently in ELISA, WB, and IHC for IRF6 detection and localization.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line HaCaT
Immunofluorescent staining of human cell line HaCaT shows localization to nucleoplasm, cytosol & cell junctions.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63121/1576_F9_2_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63121/1685_F8_1_blue_red_green.jpg
Normal Tissue
Figure 3 Cerebral cortex
Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Glial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Nuclear
Neuronal cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63121/154587_B_9_5.jpg
Normal Tissue
Figure 4 Colon
Glandular cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63121/154587_A_9_3.jpg
Normal Tissue
Figure 5 Liver
Hepatocytes
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63121/154587_A_7_4.jpg
Normal Tissue
Figure 6 Kidney
Cells in tubules
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63121/154587_A_8_5.jpg
Normal Tissue
Figure 7 Testis
Spermatogonia cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63121/154587_A_6_6.jpg
Normal Tissue
Figure 8 Skin
Epidermal cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranousnucl ear
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/63121/154587_B_5_8.jpg
RNA Expression
Figure 9 RNA cell line category: Cell line enhanced (A-431, HaCaT, HBEC3-KT, hTCEpi, hTERT-HME1, RT4)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000117595-IRF6
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Specifications
- Host Animal
- Mouse
- Applications
- WB, ICC, IF, FC
- Specificity
- IRF6
- Target
- IRF6
- Species Reactivity
- Human
- Type
- Mouse IgG1
- Purity
- >95%, determined by SDS-PAGE
- Purification
- Affinity chromatography purified
- Format
- Lyophilized
- Buffer
- PBS, pH 7.3, with 8% trehalose
- Preservative
- No preservative
- Storage
- Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics.
Target
- Introduction
- This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants.
- Alternative Names
- LPS, PIT, PPS, VWS, OFC6, PPS1, VWS1
- Gene ID
- 3664
- UniProt ID
- O14896
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Downloadable Resources
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Recommended Dilution Buffer
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "IRF6"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-1969-sdAb | Recombinant Anti-human IRF6 VHH Single Domain Antibody | ELISA, Neut, ICC, FC | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| DrMAB-356 | Recombinant Human Anti-Human IRF6 Antibody, clone U69 | IP, IF | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1858 | Hi-Affi™ Recombinant Rabbit Anti-IRF6 Monoclonal Antibody (DS1858AB) | WB, IHC-P, ICC, IF | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC1956 | PE-A2/Human IRF6 (GLYPGLIWL) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC1983 | PE-A*02:01/Human IRF6 (GLYPGLIWL) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0332-CN-VHH | Camelid Anti-IRF6 Recombinant Single Domain Antibody (FAMAB-0332-CN-VHH) | ELISA | Camelid VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0333-CN-VHH | Camelid Anti-IRF6 Recombinant Single Domain Antibody (FAMAB-0333-CN-VHH) | ELISA | Camelid VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0334-CN-VHH | Camelid Anti-IRF6 Recombinant Single Domain Antibody (FAMAB-0334-CN-VHH) | ELISA | Camelid VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-0872-CN | Recombinant Rabbit Anti-IRF6 Monoclonal Antibody (CBACN-324) | WB, IF, IHC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-CJ130 | Rabbit Anti-IRF6 Recombinant Antibody (VS3-CJ130) | WB, ICC, IF, IHC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-FY1584 | Mouse Anti-IRF6 Recombinant Antibody (clone ZN106) | IHC-P | Mouse IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1147 | Anti-IRF6 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3594 | Anti-Mouse IRF6 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0625-FY1436 | Human Anti-IRF6 Recombinant Antibody (clone 2506W1331) | ELISA, Spiked IP, IF | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3593 | Anti-Human IRF6 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1225-XY139 | Mouse Anti-IRF6 Recombinant Antibody (VS-1225-XY139) | ICC, IF | Mouse IgG3 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1225-XY140 | Mouse Anti-IRF6 Recombinant Antibody (VS-1225-XY140) | WB | Mouse IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1225-XY141 | Mouse Anti-IRF6 Recombinant Antibody (VS-1225-XY141) | WB, ICC, IF, FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1225-XY143 | Rabbit Anti-IRF6 Recombinant Antibody (VS-1225-XY143) | WB, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1225-XY144 | Rabbit Anti-IRF6 Recombinant Antibody (VS-1225-XY144) | WB, ICC, IF, ELISA, IP | Rabbit IgG |
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