Mouse Anti-ITGA2 Recombinant Antibody (clone 16B4) (CAT#: FAMAB-1182CQ)
This product is a recombinant mouse antibody that recognizes ITGA2. The antibody was purified by affinity chromatography. It can be used in IP, WB, FC.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
IF
Figure 1 Identifcation of ITGA2 as a molecular target for GBM.
Representative microscopic images of immunofuorescent staining of ITGA2 in GBM and SVG-P12 cells. Scale bars represent 50 µm.
Guo, P., Moses-Gardner, A., Huang, J., Smith, E. R., & Moses, M. A. (2019). ITGA2 as a potential nanotherapeutic target for glioblastoma. Scientific reports, 9(1), 1-10.
FC
Figure 2 Identifcation of ITGA2 as a molecular target for GBM.
Cell membrane expression levels of ITGA2 and EGFR in GBM and SVG-P12 cells using fow cytometry analysis, showing increased tumorspecifcity of ITGA2 expression on GBM cells as compared to both control cells and also to the current GBM marker, EGFR.
Guo, P., Moses-Gardner, A., Huang, J., Smith, E. R., & Moses, M. A. (2019). ITGA2 as a potential nanotherapeutic target for glioblastoma. Scientific reports, 9(1), 1-10.
Block
Figure 3 Terapeutic functions of ITGA2 blockade.
The effect of ITGA2 antibody on GBM cell proliferation.
Guo, P., Moses-Gardner, A., Huang, J., Smith, E. R., & Moses, M. A. (2019). ITGA2 as a potential nanotherapeutic target for glioblastoma. Scientific reports, 9(1), 1-10.
Cyt
Figure 4 GBM-targeted therapy of ITGA2-Dox-LP.
Cytotoxicity of ITGA2-LP (vehicle), IgG-Dox-LP, and ITGA2-Dox-LP in A172 cells.
Guo, P., Moses-Gardner, A., Huang, J., Smith, E. R., & Moses, M. A. (2019). ITGA2 as a potential nanotherapeutic target for glioblastoma. Scientific reports, 9(1), 1-10.
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human α2 integrin subunit
- Species Reactivity
- Human
- Clone
- 16B4
- Applications
- IF, FC, BL, Cyt
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Flow Cytometry, Cytotoxicity, Blocking and Immunofluorescence.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-251 | Anti-Human ITGA2 Recombinant Antibody (Vatelizumab) | IF, IP, Neut, FuncS, ELISA, FC, ICC | IgG4 - kappa |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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