Mouse Anti-KLRK1 Recombinant Antibody (clone 6E5A7) (CAT#: VS11-QX88)
This product is a recombinant mouse antibody that recognizes KLRK1. This antibody can be used for the following applications: FC, Block. The antibody 6E5A7 blocks the interaction between ligand and receptor.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/68877/1695_B6_3_cr57d8507991e89_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/68877/1695_B6_3_cr57d8507991e89_selected.jpg
Figure 2 High expression in spleen.
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/21896/ihc_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/21896/ihc_selected.jpg
Figure 3 Low expression in cerebral cortex.
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/21896/49188_B_8_5_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/21896/49188_B_8_5_val_selected.jpg
Figure 4 Lymph node
(Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/21896/49188_A_7_8.jpg
(Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/21896/49188_A_7_8.jpg
Figure 5 Spleen
(Cells in red pulp Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/21896/49188_B_7_4.jpg
(Cells in red pulp Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/21896/49188_B_7_4.jpg
Figure 6 RNA cell line category: Cell line enriched (U-698)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000213809-KLRK1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000213809-KLRK1
Specifications
- Immunogen
- Soluble NKG2-D fragments containing amino acids from 64-462 and 123-462.
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- Mouse IgG2b, κ
- Specificity
- Human KLRK1
- Species Reactivity
- Human
- Clone
- 6E5A7
- Applications
- FC, Block
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A purified
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- 1 mg/mL (Please refer to the vial label for the specific concentration.)
- Buffer
- 0.2 μm filtered solution in PBS
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipped at 4°C.
Target
- Alternative Names
- Killer Cell Lectin Like Receptor K1; Killer Cell Lectin-Like Receptor Subfamily K, Member 1; NKG2-D-Activating NK Receptor; NK Cell Receptor D; D12S2489E; NKG2D; DNA Segment On Chromosome 12 (Unique) 2489 Expressed Sequence
- Gene ID
- 22914
- UniProt ID
- P26718
- Long Name
- NKG2-D type II integral membrane protein
- Cellular Localization
- Plasma membrane
- Function
- Functions as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress-inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells.
Recommended Products
Isotype Control
Recommended Dilution Buffer
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Human Antibody Products
Neutralizing Antibody Products
Blocking Antibody Products
IgG Antibody Products
Single Domain Antibody Products
ScFv Antibody Products
Fab Antibody Products
ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0002CL | Human Anti-KLRK1 Recombinant Antibody (TAB-0002CL) | ELISA, WB, FC, RIA, Block, IA | Human IgG4 |
| TAB-0002CL-S(P) | Human Anti-KLRK1 Recombinant Antibody; scFv Fragment (TAB-0002CL-S(P)) | ELISA, WB, FC, RIA, Block, IA | Human scFv |
| TAB-0002CL-F(E) | Human Anti-KLRK1 Recombinant Antibody; Fab Fragment (TAB-0002CL-F(E)) | ELISA, WB, FC, RIA, Block, IA | Human Fab |
| TAB-520MZ-S(P) | Anti-Human KLRK1 Recombinant Antibody scFv Fragment (KYK-1.0) | SDS-PAGE, ELISA | Human antibody |
| TAB-521MZ-S(P) | Anti-Human KLRK1 Recombinant Antibody scFv Fragment (KYK-2.0) | ELISA | Human antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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