Mouse Anti-KLRK1 Recombinant Antibody (VS3-FY2752) (CAT#: VS3-FY2752)

• Host Species
• Mouse

• Type
• Mouse IgG

• Specificity
• Killer cell lectin like receptor K1 of human and rat origins

• Species Reactivity
• Human, Rat

• Applications
• WB, FC, ELISA

• Conjugate
• Unconjugated, FITC

• MW
• The molecular weight of the target protein is approximately 25.3 kDa.

• Related Disease
• Immune diseases and cancer

• Clonality
• Monoclonal Antibody

• Format
• Liquid

• Concentration
• Please refer to the vial label for the specific concentration.

• Storage
• Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

• Application Notes
• Western Blot: 1/500-1/2000
  Flow cytometry: 1/50-1/200
  ELISA: 1/1000-1/10000

• Alternative Names
• Killer Cell Lectin Like Receptor K1; Killer Cell Lectin-Like Receptor Subfamily K, Member 1; NKG2-D-Activating NK Receptor; NK Cell Receptor D; D12S2489E; NKG2D; DNA Segment On Chromosome 12 (Unique) 2489 Expressed Sequence

• Gene ID
• 22914

• Cellular Localization
• Cell membrane

• Post Translation Modifications
• Glycosylation at Asn131, Asn163, and Asn202
  Modification sites at PhosphoSitePlus
  Glycosylation from GlyGen 3 sites

• Protein Refseq
• NP_031386.2

• Function
• Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation.
  Stimulates perforin-mediated elimination of ligand-expressing tumor cells.
  Signaling involves calcium influx, culminating in the expression of TNF-alpha.
  Participates in NK cell-mediated bone marrow graft rejection.

Secondary Antibody

• 2ND-040CQ
• Goat Anti-Mouse IgG (H&L) Antibody

Isotype Control

• MRO-A1591-YJ
• Mouse IgG Isotype control, Polyclonal

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