Mouse Anti-KLRK1 Recombinant Antibody (VS3-FY2752)
CAT#: VS3-FY2752
The anti-KLRK1 product is a recombinant mouse monoclonal antibody that binds to CD314 protein, a calculated weight of 25.3 kDa. It cross-reacts with human, rat. This monoclonal antibody is potential for conducting research on Immune diseases and cancer. This monoclonal antibody can be used in Western Blot, Flow cytometry, ELISA.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/68877/1695_B6_3_cr57d8507991e89_selected.jpg
Normal Tissue
Figure 2 High expression in spleen.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/21896/ihc_selected.jpg
Normal Tissue
Figure 3 Low expression in cerebral cortex.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/21896/49188_B_8_5_val_selected.jpg
Normal Tissue
Figure 4 Lymph node
Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/21896/49188_A_7_8.jpg
Normal Tissue
Figure 5 Spleen
Cells in red pulp Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/21896/49188_B_7_4.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enriched (U-698)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000213809-KLRK1
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Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Killer cell lectin like receptor K1 of human and rat origins
- Species Reactivity
- Human, Rat
- Applications
- WB, FC, ELISA
- Conjugate
- Unconjugated, FITC
- MW
- The molecular weight of the target protein is approximately 25.3 kDa.
- Related Disease
- Immune diseases and cancer
Product Property
- Clonality
- Monoclonal Antibody
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/2000
Flow cytometry: 1/50-1/200
ELISA: 1/1000-1/10000
Target
- Alternative Names
- Killer Cell Lectin Like Receptor K1; Killer Cell Lectin-Like Receptor Subfamily K, Member 1; NKG2-D-Activating NK Receptor; NK Cell Receptor D; D12S2489E; NKG2D; DNA Segment On Chromosome 12 (Unique) 2489 Expressed Sequence
- Gene ID
- 22914
- Cellular Localization
- Cell membrane
- Post Translation Modifications
- Glycosylation at Asn131, Asn163, and Asn202
Modification sites at PhosphoSitePlus
Glycosylation from GlyGen 3 sites
- Protein Refseq
- NP_031386.2
- Function
- Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation.
Stimulates perforin-mediated elimination of ligand-expressing tumor cells.
Signaling involves calcium influx, culminating in the expression of TNF-alpha.
Participates in NK cell-mediated bone marrow graft rejection.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "KLRK1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1686z | Mouse Anti-KLRK1 Recombinant Antibody (clone 1H3) | FC, ICC, IF, IHC, IP, FuncS | Mouse IgG1 |
| HPAB-0327-CN | Human Anti-KLRK1 Recombinant Antibody (HPAB-0327-CN) | ELISA, FC, Block | Human IgG4 |
| HPAB-0328-CN | Human Anti-KLRK1 Recombinant Antibody (HPAB-0328-CN) | ELISA, FC, Block | Human IgG4 |
| HPAB-0329-CN | Human Anti-KLRK1 Recombinant Antibody (HPAB-0329-CN) | ELISA, FC, Block | Human IgG4 |
| HPAB-0505-WJ | Human Anti-KLRK1 Recombinant Antibody (HPAB-0505-WJ) | ELISA, WB | Human IgG4 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0002CL | Human Anti-KLRK1 Recombinant Antibody (TAB-0002CL) | ELISA, WB, FC, RIA, Block, IA | Human IgG4 |
| TAB-0002CL-F(E) | Human Anti-KLRK1 Recombinant Antibody; Fab Fragment (TAB-0002CL-F(E)) | ELISA, WB, FC, RIA, Block, IA | Human Fab |
| TAB-520MZ | Anti-Human KLRK1 Recombinant Antibody (KYK-1.0) | ELISA | Human antibody |
| TAB-520MZ-S(P) | Anti-Human KLRK1 Recombinant Antibody scFv Fragment (KYK-1.0) | SDS-PAGE, ELISA | Human antibody |
| TAB-521MZ-S(P) | Anti-Human KLRK1 Recombinant Antibody scFv Fragment (KYK-2.0) | ELISA | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1660CQ | Recombinant Mouse Anti-KLRK1 Antibody (5C6) | FC, FuncS, IHC, IP, Neut | IgG2a |
| NEUT-1661CQ | Recombinant Armenian hamster Anti-Klrk1 Antibody (NEUT-1661CQ) | FC, FuncS, Neut | IgG |
| NEUT-1663CQ | Recombinant Rat Anti-Klrk1 Antibody (MI6) | FC, FuncS, Neut | IgG2a, λ |
| NEUT-1667CQ | Recombinant Mouse Anti-KLRK1 Antibody (CBL019) | FC, WB, Neut | IgG1 |
| NEUT-1668CQ | Recombinant Mouse Anti-KLRK1 Antibody (CBL703) | WB, FC, Costim, CyTOF, Neut | IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1662CQ | Recombinant Rat Anti-Klrk1 Antibody (VMC202) | FC, BL | IgG1, κ |
| NEUT-1664CQ | Recombinant Hamster Anti-Klrk1 Antibody (VMC203) | BL | IgG |
| NEUT-1665CQ | Recombinant Hamster Anti-Klrk1 Antibody (MAB0840) | BL, FC | IgG2 |
| NEUT-1666CQ | Recombinant Rat Anti-Klrk1 Antibody (CBL347) | BL, CyTOF, FC, WB | IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0620-CN | Llama Anti-KLRK1 Recombinant Antibody (HPAB-0620-CN) | ELISA, FC | Llama VHH |
| HPAB-0621-CN | Llama Anti-KLRK1 Recombinant Antibody (HPAB-0621-CN) | ELISA, FC | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0327-CN-S(P) | Human Anti-KLRK1 Recombinant Antibody; scFv Fragment (HPAB-0327-CN-S(P)) | ELISA, FC, Block | Human scFv |
| HPAB-0328-CN-S(P) | Human Anti-KLRK1 Recombinant Antibody; scFv Fragment (HPAB-0328-CN-S(P)) | ELISA, FC, Block | Human scFv |
| HPAB-0329-CN-S(P) | Human Anti-KLRK1 Recombinant Antibody; scFv Fragment (HPAB-0329-CN-S(P)) | ELISA, FC, Block | Human scFv |
| HPAB-0726-FY-F(E) | Mouse Anti-KLRK1 Recombinant Antibody (clone AB121); scFv Fragment | ELISA | Mouse scFv |
| HPAB-0505-WJ-S(P) | Human Anti-KLRK1 Recombinant Antibody; scFv Fragment (HPAB-0505-WJ-S(P)) | ELISA, WB | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0327-CN-F(E) | Human Anti-KLRK1 Recombinant Antibody; Fab Fragment (HPAB-0327-CN-F(E)) | ELISA, FC, Block | Human Fab |
| HPAB-0328-CN-F(E) | Human Anti-KLRK1 Recombinant Antibody; Fab Fragment (HPAB-0328-CN-F(E)) | ELISA, FC, Block | Human Fab |
| HPAB-0329-CN-F(E) | Human Anti-KLRK1 Recombinant Antibody; Fab Fragment (HPAB-0329-CN-F(E)) | ELISA, FC, Block | Human Fab |
| HPAB-0726-FY-S(P) | Mouse Anti-KLRK1 Recombinant Antibody (clone AB121); Fab Fragment | ELISA | Mouse Fab |
| HPAB-0505-WJ-F(E) | Human Anti-KLRK1 Recombinant Antibody; Fab Fragment (HPAB-0505-WJ-F(E)) | ELISA, WB | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY18 | Human Anti-KLRK1 (clone KYK-2.0) scFv-Fc Chimera | ELISA, FC | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC127 | Recombinant Anti-KLRK1 Vesicular Antibody, EV Displayed (VS-0425-YC127) | Cyt, ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3816 | Anti-KLRK1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY3817 | Anti-Rat KLRK1 Immunohistochemistry Kit | IHC |
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