AibGenesis™ Rabbit Anti-LAMP2 Recombinant Antibody (AibG-Rb-AM231)
CAT#: VS14-YC432
Designed for high-performance research, the AI-derived anti-LAMP2 mAb exhibits an exceptional binding profile for the LAMP2 protein. LAMP2 (Lysosome-Associated Membrane Protein 2) is a highly glycosylated protein essential for lysosomal stability and fusion. It is a critical mediator of chaperone-mediated autophagy (CMA) and macroautophagy, facilitating the degradation of cellular debris.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/29100/598_H2_2_selected.jpg
Normal Tissue
Figure 2 IHC staining of human placenta
Immunohistochemical staining of human placenta shows strong cytoplasmic positivity in trophoblastic cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/29100/ihc_selected.jpg
Normal Tissue
Figure 3 IHC staining of human liver
Immunohistochemical staining of human liver shows strong cytoplasmic positivity in hepatocytes.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/5272/ihc_selected.jpg
Normal Tissue
Figure 4 Cerebral cortex
Glial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/29100/89892_B_7_5.jpg
Normal Tissue
Figure 5 Colon
Endothelial cells
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Glandular cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/29100/89892_A_9_3.jpg
Normal Tissue
Figure 6 Kidney
Collecting ducts
Staining: Medium
Intensity: Strong
Quantity: <25%
Distal tubules
Staining: Medium
Intensity: Strong
Quantity: <25%
Proximal tubules (cell body)
Staining: High
Intensity: Strong
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/29100/89892_A_8_5.jpg
Normal Tissue
Figure 7 Testis
Leydig cells
Staining: High
Intensity: Strong
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/29100/89892_A_6_6.jpg
Normal Tissue
Figure 8 Lymph node
Germinal center cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/29100/89892_A_9_8.jpg
RNA Expression
Figure 9 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000005893-LAMP2
❮
❯
Specifications
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- LAMP2
- Species Reactivity
- Human, Mouse, Rat
- Clone
- AibG-Rb-AM231
- Applications
- Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity purified
- Buffer
- PBS (pH 7.4), 150 mM NaCl and 50% Glycerol
- Preservative
- 0.02% Sodium azide
- Storage
- Store at 4˚C short term. Aliquot and store at -20˚C long term. Avoid freeze/thaw cycles.
Applications
- Application Notes
- Western Blot (WB): 1/500-1/2000
Immunohistochemistry (IHC): 1/50-1/200
Immunocytochemistry (ICC): 1/50-1/200
Immunofluorescence (IF): 1/50-1/200
Target
- Alternative Names
- Lysosomal Associated Membrane Protein 2
2
3
5
CD107 Antigen-Like Family Member B 3
4
LAMP-2 3
4
LGP-96 3
4
Lysosome-Associated Membrane Glycoprotein 2 3
Lysosomal-Associated Membrane Protein 2 2
Lysosome-Associated Membrane Protein 2 4
CD107b Antigen 4
CD107b 3
LGP110 3
LAMPB 3
- Gene ID
- 3920
- UniProt ID
- P13473
- Long Name
- Lysosomal Associated Membrane Protein 2
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3425z | Mouse Anti-LAMP2 Recombinant Antibody (clone 38C1) | WB, ELISA, FC, IHC | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0951CT | Recombinant Mouse anti-Human LAMP2 Monoclonal antibody (I5C5) | FC, IHC-Fr |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2011 | Hi-Affi™ Recombinant Rabbit Anti-LAMP2 Monoclonal Antibody (DS2011AB) | WB, ICC, IP | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-0917-CN | Recombinant Mouse Anti-LAMP2 Monoclonal Antibody (C9-9) | WB, IF, IHC, FC | Mouse IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-0918-CN | Recombinant Rabbit Anti-LAMP2 Monoclonal Antibody (CBACN-343) | WB, IHC, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-2007-CN | Rabbit Anti-LAMP2 Polyclonal Antibody (MRO-2007-CN) | WB, IHC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC1043 | AbPlus™ Anti-LAMP2 Magnetic Beads (VS-0724-YC1043) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY302 | Mouse Anti-NHP LAMP2 Recombinant Antibody (clone H4B4) | WB, IF, FC | Mouse IgG2b |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1225 | Anti-LAMP2 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC645 | CytoStream™ Mouse Anti-LAMP2 Recombinant Antibody (VS13-YC645) | WB, ICC, IF, IHC-P, FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3941 | Anti-Mouse LAMP2 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3940 | Anti-Human LAMP2 Immunohistochemistry Kit | IHC |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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