Mouse Anti-LMNA Recombinant Antibody (clone 13A4D4) (CAT#: VS1-YJ190)
This product is a mouse antibody that recognizes LMNA.
Specific Inquiry
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line PC-3
(Immunofluorescent staining of human cell line PC-3 shows localization to nuclear speckles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6523/1905_E12_1_selected.jpg
(Immunofluorescent staining of human cell line PC-3 shows localization to nuclear speckles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6523/1905_E12_1_selected.jpg
Figure 2 IHC staining of human epididymis
(Immunohistochemical staining of human epididymis shows strong nuclear membrane positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6660/ihc_selected.jpg
(Immunohistochemical staining of human epididymis shows strong nuclear membrane positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6660/ihc_selected.jpg
Figure 3 IHC staining of human rectum
(Immunohistochemical staining of human rectum shows strong nuclear membrane positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4022/ihc_selected.jpg
(Immunohistochemical staining of human rectum shows strong nuclear membrane positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4022/ihc_selected.jpg
Figure 4 Cerebral cortex
(Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Glial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Neuronal cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4022/12055_B_8_5.jpg
(Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Glial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Neuronal cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4022/12055_B_8_5.jpg
Figure 5 Colon
(Endocrine cells
Staining: High
Intensity: Strong
Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Enterocytes
Staining: High
Intensity: Strong
Quantity:>75%
Enterocytes - Microvilli
Staining: High
Intensity: Strong
Fibroblasts
Staining: High
Intensity: Strong
Goblet cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Mucosal lymphoid cells
Staining: High
Intensity: Strong
Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4022/12055_A_9_3.jpg
(Endocrine cells
Staining: High
Intensity: Strong
Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Enterocytes
Staining: High
Intensity: Strong
Quantity:>75%
Enterocytes - Microvilli
Staining: High
Intensity: Strong
Fibroblasts
Staining: High
Intensity: Strong
Goblet cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Mucosal lymphoid cells
Staining: High
Intensity: Strong
Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4022/12055_A_9_3.jpg
Figure 6 Liver
(Cholangiocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Hepatocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4022/12055_A_7_4.jpg
(Cholangiocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Hepatocytes
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4022/12055_A_7_4.jpg
Figure 7 Kidney
(Cells in glomeruli
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Cells in tubules
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4022/12055_A_8_5.jpg
(Cells in glomeruli
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Cells in tubules
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4022/12055_A_8_5.jpg
Figure 8 Testis
(Leydig cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Peritubular cells
Staining: High
Intensity: Strong
Quantity:>75%
Sertoli cells
Staining: High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4022/12055_A_6_6.jpg
(Leydig cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Peritubular cells
Staining: High
Intensity: Strong
Quantity:>75%
Sertoli cells
Staining: High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4022/12055_A_6_6.jpg
Figure 9 Skin
(Cells in basal layer
Staining: High
Intensity: Strong
Quantity:>75%
Cells in granular layer
Staining: High
Intensity: Strong
Quantity: 75%-25%
Cells in spinous layer
Staining: High
Intensity: Strong
Quantity: 75%-25%
Endothelial cells
Staining: High
Intensity: Strong
Fibrohistiocytic cells
Staining: High
Intensity: Strong
Langerhans cells
Staining: High
Intensity: Strong
Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4022/12055_B_9_1.jpg
(Cells in basal layer
Staining: High
Intensity: Strong
Quantity:>75%
Cells in granular layer
Staining: High
Intensity: Strong
Quantity: 75%-25%
Cells in spinous layer
Staining: High
Intensity: Strong
Quantity: 75%-25%
Endothelial cells
Staining: High
Intensity: Strong
Fibrohistiocytic cells
Staining: High
Intensity: Strong
Langerhans cells
Staining: High
Intensity: Strong
Quantity: 75%-25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4022/12055_B_9_1.jpg
Figure 10 Lymph node
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4022/12055_A_7_8.jpg
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4022/12055_A_7_8.jpg
Figure 11 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000160789-LMNA
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000160789-LMNA
Specifications
- Immunogen
- Synthetic peptide conjugated to KLH derived from within residues 604 - 611 (GAQSPQNC) at the C terminus of Human Progerin
- Host Species
- Mouse
- Type
- Mouse IgG1, κ
- Specificity
- Human LMNA
- Species Reactivity
- Human
- Clone
- 13A4D4
- Applications
- WB, ICC, IF, IP
Product Property
- Purification
- Protein G purified
- Concentration
- See the COA
- Buffer
- See the COA
- Storage
- Store at 4°C for short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Western Blot, Immunocytochemistry, Immunofluorescence, Immunoprecipitation.
Target
- Alternative Names
- FPL; IDC; LFP; CDDC; EMD2; FPLD; HGPS; LDP1; LMN1; LMNC; MADA; PRO1; CDCD1; CMD1A; FPLD2; LMNL1; CMT2B1; LGMD1B; lamin; 70 kDa lamin epididymis secretory sperm binding protein lamin A/C-like 1 mandibuloacral dysplasia type A prelamin-A/C renal carcinoma antigen NY-REN-32
- Gene ID
- 4000
- UniProt ID
- P02545
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1769MZ | Recombinant Mouse Anti-Human LMNA Antibody (clone KPM3) | FC, ICC/IF, IHC-Fr, IHC-P, IP, WB | Mouse antibody |
| ZG-0958F | Mouse Anti-LMNA Recombinant Antibody (clone 131C3) | FC, ICC, IHC-Fr | Mouse IgG1 |
| ZG-0960F | Mouse Anti-LMNA Recombinant Antibody (clone 133A2) | FC, ICC, IHC-Fr | Mouse IgG3 |
| VS3-QX693 | Mouse Anti-LMNA Recombinant Antibody (clone 3D6-F4-B7) | WB | Mouse IgG2a |
| VS3-FY850 | Recombinant Rabbit Anti-LMNA Antibody (clone R06-7H5) | WB, IHC-Fr, IHC-P, ICC, IF, IP | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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