Human Anti-LYZ Antibody (HuLys11), CHO Stable Cell Pool

Name: Human Anti-LYZ Antibody (HuLys11), CHO Stable Cell Pool
SKU: VS-1025-QX537
Rating: 5 (1 reviews)

CAT#: VS-1025-QX537

This CHO Stable Cell Pool represents a genetically engineered Chinese Hamster Ovary (CHO) cell population specifically designed for the robust and consistent expression of recombinant HuLys11. HuLys11 is a Human monoclonal antibody that targets LYZ. This cell pool was generated through the stable integration of genes encoding the heavy and light chains of HuLys11 into the CHO genome, followed by selection and enrichment for high-expressing cells. This cell pool provides rapid production of research-grade antibodies for non-GLP preclinical studies.

Gene Expression

Subcellular Location and Protein Expression Figure 1 IF staining of human cell line Hep G2

Immunofluorescent staining of human cell line Hep G2 shows localization to nucleoplasm, the Golgi apparatus & actin filaments.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/66182/1763_E3_3_selected.jpg

Normal Tissue Figure 2 IHC staining of human salivary gland

High expression. RNA expression: 21115.5 nTPM

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/48284/124814_B_3_1_val_selected.jpg

Normal Tissue Figure 3 IHC staining of human skeletal muscle

Low expression. RNA expression: 34.0 nTPM

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/48284/124814_B_3_6_val_selected.jpg

Normal Tissue Figure 4 Colon

Mucosal lymphoid cells
Staining: Low
Intensity: Moderate
Quantity: <25%

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/48284/124814_A_7_3.jpg

Normal Tissue Figure 5 Kidney

Cells in tubules
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/48284/124814_A_9_5.jpg

Normal Tissue Figure 6 Testis

Leydig cells
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/55/231_A_5_6.jpg

Normal Tissue Figure 7 Lymph node

Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/48284/124814_A_7_8.jpg

RNA Expression Figure 8 RNA cell line category: Cell line enriched (OE19)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000090382-LYZ

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Specifications

Host Cell
CHO

Product Type
Stable Cell Pool

Cell Viability
>90%

Mycoplasma Detection
Negative

Bacteria Detection
Negative

Growth Properties
Suspension

Culture Medium
VersaCHO™ Medium (VS-1025-QX582)

Complete Growth Medium
VersaCHO™ Medium (VS-1025-QX582), VersaCHO™ Feed Medium (VS-1025-QX583), VersaCHO™ Feed Supplement (VS-1025-QX584)

Freeze Medium
90% VersaCHO™ Medium, 10% DMSO

Growth Conditions
37°C, 5% CO₂

Size
Each vial contains at least 1×10^6 cells in 1 mL

Shipping
Dry ice

Storage
Store in liquid nitrogen immediately upon receipt. Avoid multiple freeze/thaw cycles. Utilize cells within one year of the delivery date.

Antibody Overview

Host Species
Human

Antibody Type
Human IgG1, κ

Clone
HuLys11

Target
LYZ

Species Reactivity
Chicken

Target

Alternative Names
LYZ; lysozyme (renal amyloidosis); 1; LYZC; lysozyme C; dystrophin; allergen Gal d IV; egg white lysozyme; 4-beta-N-acetylmuramidase C; 1,4-beta-N-acetylmuramidase C

Gene ID
396218

UniProt ID
P00698

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Datasheet

Datasheet - VS-1025-QX537.pdf

MSDS

MSDS - VS-1025-QX537.pdf

COA

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