Recombinant Anti-MBP (AA 65-92 x AA 130-156) Biparatopic Antibody, Tandem scFv (Clone E6 x Clone D1) (CAT#: VS-0525-YC123)

The Recombinant Anti-MBP (AA 65-92 x AA 130-156) Biparatopic Antibody, Tandem scFv (Clone E6 x Clone D1) is a biparatopic antibody (bpAb) that binds two distinct Myelin Basic Protein (MBP) epitopes. Its tandem scFv design positions the E6 scFv (targeting amino acids 65-92 of MBP) N-terminally to the D1 scFv (specific for amino acids 130-156 of MBP).

Specific Inquiry
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Normal Tissue
RNA Expression

Specifications

  • Host Animal 1
  • Human
  • Host Animal 2
  • Human
  • Specificity
  • EBV MBP
  • Species Reactivity
  • EBV
  • Type
  • Tandem scFv
  • Valency
  • 1 + 1
  • Clone 1
  • E6
  • Clone 2
  • D1
  • Epitope 1
  • aa 65-92
  • Epitope 2
  • aa 130-156
  • Purity
  • >90%
  • Purification
  • Affinity purified
  • Applications
  • ELISA, IP, WB
  • Concentration
  • Lot specific
  • Buffer
  • PBS, pH 7.4
  • Preservative
  • No preservatives
  • Storage
  • Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid freeze-thaw cycles.
  • Long Name
  • Myelin Basic Protein

Target

  • Introduction
  • The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases.
  • Alternative Names
  • MBP

Related Resources

  • Related Diseases

Downloads

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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