Recombinant Anti-MBP (AA 65-92 x AA 130-156) Biparatopic Antibody, Tandem scFv (Clone E6 x Clone D1) (CAT#: VS-0525-YC123)
The Recombinant Anti-MBP (AA 65-92 x AA 130-156) Biparatopic Antibody, Tandem scFv (Clone E6 x Clone D1) is a biparatopic antibody (bpAb) that binds two distinct Myelin Basic Protein (MBP) epitopes. Its tandem scFv design positions the E6 scFv (targeting amino acids 65-92 of MBP) N-terminally to the D1 scFv (specific for amino acids 130-156 of MBP).
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression

Figure 1 IF staining of human cell line HaCaT
(Immunofluorescent staining of human cell line HaCaT shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/64368/1577_H5_1_selected.jpg
(Immunofluorescent staining of human cell line HaCaT shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/64368/1577_H5_1_selected.jpg

Figure 2 Cerebral cortex
(Endothelial cells
Staining:
Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous
nuclear
Neuropil
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2300/6024_B_9_5.jpg
(Endothelial cells
Staining:
Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous
nuclear
Neuropil
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2300/6024_B_9_5.jpg

Figure 3 Caudate
(Glial cells
Staining:
High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/
membranous
nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2300/6024_B_8_7.jpg
(Glial cells
Staining:
High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/
membranous
nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2300/6024_B_8_7.jpg

Figure 4 RNA cell line category: Cell line enhanced (HL-60, SK-MEL-30)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000197971-MBP
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000197971-MBP

Figure 4 RNA cell line category: Cell line enhanced (HL-60, SK-MEL-30)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000197971-MBP
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000197971-MBP
Specifications
- Host Animal 1
- Human
- Host Animal 2
- Human
- Specificity
- EBV MBP
- Species Reactivity
- EBV
- Type
- Tandem scFv
- Valency
- 1 + 1
- Clone 1
- E6
- Clone 2
- D1
- Epitope 1
- aa 65-92
- Epitope 2
- aa 130-156
- Purity
- >90%
- Purification
- Affinity purified
- Applications
- ELISA, IP, WB
- Concentration
- Lot specific
- Buffer
- PBS, pH 7.4
- Preservative
- No preservatives
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid freeze-thaw cycles.
- Long Name
- Myelin Basic Protein
Target
- Introduction
- The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases.
- Alternative Names
- MBP
Related Resources
Downloads
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IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1126z | Mouse Anti-MBP Recombinant Antibody (clone 34D11) | WB, FuncS | Mouse IgG |
FAMAB-0216CQ | Mouse Anti-MBP Recombinant Antibody (clone 845D3) | ELISA, WB, IB | Mouse IgG1, κ |
VS3-FY902 | Recombinant Mouse Anti-MBP Antibody (clone 10D5-4A3-9G5) | IHC-P | Mouse IgG1 |
VS3-FY903 | Recombinant Rabbit Anti-MBP Antibody (clone R03-8D1) | WB | Rabbit IgG |
VS3-FY904 | Recombinant Rabbit Anti-MBP Antibody (clone R07-4I6) | WB | Rabbit IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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