MBP

Anti-MBP Products

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BV421-H-2 IAb/Mouse MBP (TTHYGSLPQKSQ) MHC Tetramer (MHC-YF1532)
- Class: Class II
- Antigen: MBP
- Antigen Species: Mouse
- Peptide: TTHYGSLPQKSQ
- Conjugate: BV421
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Mouse Anti-MBP Recombinant Antibody (ZG-0271C) (ZG-0271C)
- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, ELISA
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Recombinant Human Anti-MBP Soluble TCR (clone Hy.2E11) (scTCR-194CQ-S(P))
- Species Reactivity: Human
- Epitope: ENPVVHFFKNIVTPR
- MHC: HLA-DRB1*1501
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Recombinant Human Anti-MBP Soluble TCR (scTCR-195CQ-S(P)) (scTCR-195CQ-S(P))
- Species Reactivity: Human
- Epitope: aa 85-99
- MHC: HLA-DR2
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Recombinant Human Anti-MBP Soluble TCR (scTCR-196CQ-S(P))
- Species Reactivity: Human
- Epitope: KIFKLGGRDSRSGSPMARR
- MHC: HLA-DR13
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Recombinant Human Anti-MBP Soluble TCR (clone MS2-3C8) (scTCR-197CQ-S(P))
- Species Reactivity: Human
- Epitope: aa 111-129
- MHC: HLA-DR4
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Recombinant Human Anti-MBP Soluble TCR (scTCR-198CQ-S(P)) (scTCR-198CQ-S(P))
- Species Reactivity: Human
- Epitope: aa 84-102
- MHC: HLA-DR2b
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Recombinant Human Anti-MBP Soluble TCR (scTCR-199CQ-S(P)) (scTCR-199CQ-S(P))
- Species Reactivity: Human
- Epitope: ENPVVHFFKNIVTPR
- MHC: HLA-DR2b
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Mouse Anti-MBP Recombinant Antibody (clone IN-1) (FAMAB-0107-CN)
- Derivation: Mouse
- Species Reactivity: Rat
- Type: Mouse IgM, Κ
- Application: WB, IF, IP, Block
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Recombinant Human Anti-MBP Antibody (E2) (FAMAB-0217-CN)
- Derivation: Phage display library
- Species Reactivity: Human, EBV
- Type: Human IgG1
- Application: WB, ELISA, IP
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Recombinant Human Anti-MBP Antibody (F11) (FAMAB-0218-CN)
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human IgG1
- Application: WB, ELISA, IP
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Recombinant Human Anti-MBP Antibody (E6) (FAMAB-0219-CN)
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human IgG1
- Application: WB, ELISA, IP
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Recombinant Human Anti-MBP Antibody (D1) (FAMAB-0220-CN)
- Derivation: Phage display library
- Species Reactivity: EBV
- Type: Human IgG1
- Application: WB, ELISA, IP
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Recombinant Human Anti-MBP Antibody (B5V6) (FAMAB-0221-CN)
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human IgG1
- Application: WB, ELISA, IP
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Recombinant Rabbit Anti-MBP Monoclonal Antibody (JF0943) (MRO-1051-CN)
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IHC
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Anti-MBP Recombinant Soluble TCR (172.1) (scTCR-335ZP-S(P))
- Species Reactivity: Human
- Epitope: ASQKRPSQRHG + ACET(A1)
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Mouse Anti-Mbp Recombinant Soluble TCR (clone 1934.4) (scTCR-0649YC-S(P))
- Species Reactivity: Mouse
- Epitope: RGGASQYRPSQ
- MHC: H2-IAᵘ
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Mouse Anti-Mbp Recombinant Soluble TCR (clone 1.B2.D9) (scTCR-0650YC-S(P))
- Species Reactivity: Mouse
- Epitope: GGRASDYKSAH
- MHC: H2-IAᵘ
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Human Anti-MBP Recombinant Soluble TCR (clone 1F1E8hu) (scTCR-0651YC-S(P))
- Epitope: ENPVVHFFKNIVTPR
- MHC: HLA-DR2b
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Mouse Anti-MBP Recombinant Soluble TCR (clone cl19) (scTCR-0652YC-S(P))
- Epitope: RGGASQYRPSQ
- MHC: H2-IAᵘ
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Human Anti-MBP Recombinant Soluble TCR (clone (Hy.1B11)-1) (scTCR-0653YC-S(P))
- Epitope: ANPVVHFFKNIVTPR
- MHC: HLA-DRB1*15:01
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Human Anti-MBP Recombinant Soluble TCR (clone (Hy.1B11)-2) (scTCR-0654YC-S(P))
- Epitope: EAPVVHFFKNIVTPR
- MHC: HLA-DRB1*15:01
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Human Anti-MBP Recombinant Soluble TCR (clone (Hy.1B11)-3) (scTCR-0655YC-S(P))
- Epitope: ENAVVHFFKNIVTPR
- MHC: HLA-DRB5*01:01
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Human Anti-MBP Recombinant Soluble TCR (clone (Hy.1B11)-4) (scTCR-0656YC-S(P))
- Epitope: ENPAVHFFKNIVTPR
- MHC: HLA-DRB1*15:01
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Human Anti-MBP Recombinant Soluble TCR (clone (Hy.1B11)-5) (scTCR-0657YC-S(P))
- Epitope: ENPVAHFFKNIVTPR
- MHC: HLA-DRB1*15:01
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Human Anti-MBP Recombinant Soluble TCR (clone (Hy.1B11)-6) (scTCR-0658YC-S(P))
- Epitope: ENPVVDFFKNIVTPR
- MHC: HLA class II
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Human Anti-MBP Recombinant Soluble TCR (clone (Hy.1B11)-7) (scTCR-0659YC-S(P))
- Epitope: ENPVVHFFKAIVTPR
- MHC: HLA class II
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Human Anti-MBP Recombinant Soluble TCR (clone (Hy.1B11)-8) (scTCR-0660YC-S(P))
- Epitope: ENPVVHFFKDIVTPR
- MHC: HLA-DQA1*01:02/DQB1*05:02
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Human Anti-MBP Recombinant Soluble TCR (clone (Hy.1B11)-9) (scTCR-0661YC-S(P))
- Epitope: ENPVVHFFKNAVTPR
- MHC: HLA class II
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Human Anti-MBP Recombinant Soluble TCR (clone (Hy.1B11)-10) (scTCR-0662YC-S(P))
- Epitope: ENPVVHFFKNIVAPR
- MHC: HLA class II
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Human Anti-MBP Recombinant Soluble TCR (clone (Hy.1B11)-11) (scTCR-0663YC-S(P))
- Epitope: ENPVVHFFKNIVTAR
- MHC: HLA class II
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Human Anti-MBP Recombinant Soluble TCR (clone (Hy.1B11)-12) (scTCR-0664YC-S(P))
- Epitope: ENPVVHFFKNIVTPA
- MHC: HLA class II
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Human Anti-MBP Recombinant Soluble TCR (clone (Hy.1B11)-13) (scTCR-0665YC-S(P))
- Epitope: ENPVVHFFRNIVTPR
- MHC: HLA class II
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Human Anti-MBP Recombinant Soluble TCR (clone (Hy.1B11)-14) (scTCR-0666YC-S(P))
- Epitope: ENPVVHFHKNIVTPR
- MHC: HLA class II
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Human Anti-MBP Recombinant Soluble TCR (clone (Hy.1B11)-15) (scTCR-0667YC-S(P))
- Epitope: ENPVVHFIKNIVTPR
- MHC: HLA class II
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Human Anti-MBP Recombinant Soluble TCR (clone (Hy.1B11)-16) (scTCR-0668YC-S(P))
- Epitope: ENPVVHFMKNIVTPR
- MHC: HLA class II
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Human Anti-MBP Recombinant Soluble TCR (clone (Hy.1B11)-17) (scTCR-0669YC-S(P))
- Epitope: ENPVVHFVKNIVTPR
- MHC: HLA class II
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Human Anti-MBP Recombinant Soluble TCR (clone (Hy.1B11)-18) (scTCR-0670YC-S(P))
- Epitope: ENPVVHFWKNIVTPR
- MHC: HLA class II
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Human Anti-MBP Recombinant Soluble TCR (clone (Hy.1B11)-19) (scTCR-0671YC-S(P))
- Epitope: ENPVVHFYKNIVTPR
- MHC: HLA class II
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DRB1*15:01/Human Myelin basic protein (DENPVVHFFKNIVTPRTPP) MHC Monomer (MHC-YF031)
- Class: Class II
- Antigen: Myelin basic protein
- Antigen Species: Human
- Peptide: DENPVVHFFKNIVTPRTPP
- Conjugate: Biotin
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APC-H-2 IAb/Mouse MBP (TTHYGSLPQKSQ) MHC Tetramer (MHC-YF1076)
- Class: Class II
- Antigen: MBP
- Antigen Species: Mouse
- Peptide: TTHYGSLPQKSQ
- Conjugate: APC
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FITC-H-2 IAb/Mouse MBP (TTHYGSLPQKSQ) MHC Tetramer (MHC-YF1380)
- Class: Class II
- Antigen: MBP
- Antigen Species: Mouse
- Peptide: TTHYGSLPQKSQ
- Conjugate: FITC
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PE-H-2 IAb/Mouse MBP (TTHYGSLPQKSQ) MHC Tetramer (MHC-YF1228)
- Class: Class II
- Antigen: MBP
- Antigen Species: Mouse
- Peptide: TTHYGSLPQKSQ
- Conjugate: PE
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PE-DRB1*15:01/Human MBP (ENPVVHFFKNIVTPR) MHC Tetramer (MHC-LC1085)
- Class: Class II
- Antigen: MBP
- Antigen Species: Human
- Peptide: ENPVVHFFKNIVTPR
- Conjugate: PE
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PE-DRB5/Human MBP (NPVVHFFKNIVTPRTPPPSQ) MHC Tetramer (MHC-LC1136)
- Class: Class II
- Antigen: MBP
- Antigen Species: Human
- Peptide: NPVVHFFKNIVTPRTPPPSQ
- Conjugate: PE
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PE-DRB5/Human MBP (VHFFKNIVTPRTP) MHC Tetramer (MHC-LC1139)
- Class: Class II
- Antigen: MBP
- Antigen Species: Human
- Peptide: VHFFKNIVTPRTP
- Conjugate: PE
Compare

PE-H2-Aa/Human MBP (HSRGGASQYRPSQRHGTGSGSGS) MHC Tetramer (MHC-LC1193)
- Class: Class II
- Antigen: MBP
- Antigen Species: Human
- Peptide: HSRGGASQYRPSQRHGTGSGSGS
- Conjugate: PE
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APC-H2-Aa/Human MBP (HSRGGASQYRPSQRHGTGSGSGS) MHC Tetramer (MHC-LC1194)
- Class: Class II
- Antigen: MBP
- Antigen Species: Human
- Peptide: HSRGGASQYRPSQRHGTGSGSGS
- Conjugate: APC
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PE-DRB2/Human MBP (ENPVVHFFKNIVTPRGGSGGGGG) MHC Tetramer (MHC-LC1274)
- Class: Class II
- Antigen: MBP
- Antigen Species: Human
- Peptide: ENPVVHFFKNIVTPRGGSGGGGG
- Conjugate: PE
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PE-DRB5/Human MBP (VHFFKNIVTPRTPGG) MHC Tetramer (MHC-LC1307)
- Class: Class II
- Antigen: MBP
- Antigen Species: Human
- Peptide: VHFFKNIVTPRTPGG
- Conjugate: PE
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APC-DRB2/Human MBP (ENPVVHFFKNIVTPRGGSGGGGG) MHC Tetramer (MHC-LC1275)
- Class: Class II
- Antigen: MBP
- Antigen Species: Human
- Peptide: ENPVVHFFKNIVTPRGGSGGGGG
- Conjugate: APC
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APC-DRB1*15:01/Human MBP (ENPVVHFFKNIVTPR) MHC Tetramer (MHC-LC1086)
- Class: Class II
- Antigen: MBP
- Antigen Species: Human
- Peptide: ENPVVHFFKNIVTPR
- Conjugate: APC
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BV421-DRB1*15:01/Human MBP (ENPVVHFFKNIVTPR) MHC Tetramer (MHC-LC1087)
- Class: Class II
- Antigen: MBP
- Antigen Species: Human
- Peptide: ENPVVHFFKNIVTPR
- Conjugate: BV421
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APC-DRB5/Human MBP (VHFFKNIVTPRTPGG) MHC Tetramer (MHC-LC1308)
- Class: Class II
- Antigen: MBP
- Antigen Species: Human
- Peptide: VHFFKNIVTPRTPGG
- Conjugate: APC
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APC-DRB5/Human MBP (NPVVHFFKNIVTPRTPPPSQ) MHC Tetramer (MHC-LC1137)
- Class: Class II
- Antigen: MBP
- Antigen Species: Human
- Peptide: NPVVHFFKNIVTPRTPPPSQ
- Conjugate: APC
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BV421-DRB5/Human MBP (NPVVHFFKNIVTPRTPPPSQ) MHC Tetramer (MHC-LC1138)
- Class: Class II
- Antigen: MBP
- Antigen Species: Human
- Peptide: NPVVHFFKNIVTPRTPPPSQ
- Conjugate: BV421
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APC-DRB5/Human MBP (VHFFKNIVTPRTP) MHC Tetramer (MHC-LC1140)
- Class: Class II
- Antigen: MBP
- Antigen Species: Human
- Peptide: VHFFKNIVTPRTP
- Conjugate: APC
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BV421-DRB5/Human MBP (VHFFKNIVTPRTP) MHC Tetramer (MHC-LC1141)
- Class: Class II
- Antigen: MBP
- Antigen Species: Human
- Peptide: VHFFKNIVTPRTP
- Conjugate: BV421
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BV421-H2-Aa/Human MBP (HSRGGASQYRPSQRHGTGSGSGS) MHC Tetramer (MHC-LC1195)
- Class: Class II
- Antigen: MBP
- Antigen Species: Human
- Peptide: HSRGGASQYRPSQRHGTGSGSGS
- Conjugate: BV421
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BV421-DRB2/Human MBP (ENPVVHFFKNIVTPRGGSGGGGG) MHC Tetramer (MHC-LC1276)
- Class: Class II
- Antigen: MBP
- Antigen Species: Human
- Peptide: ENPVVHFFKNIVTPRGGSGGGGG
- Conjugate: BV421
Compare

BV421-DRB5/Human MBP (VHFFKNIVTPRTPGG) MHC Tetramer (MHC-LC1309)
- Class: Class II
- Antigen: MBP
- Antigen Species: Human
- Peptide: VHFFKNIVTPRTPGG
- Conjugate: BV421
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PE-DRB1*01:01/Human MBP (VDAQGTLSKIFKLGGRDSRS) MHC Tetramer (MHC-LC2118)
- Class: Class II
- Antigen: MBP
- Antigen Species: Human
- Peptide: VDAQGTLSKIFKLGGRDSRS
- Conjugate: PE
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PE-DRB1*03:01/Human MBP (VDAQGTLSKIFKLGGRDSRS) MHC Tetramer (MHC-LC2119)
- Class: Class II
- Antigen: MBP
- Antigen Species: Human
- Peptide: VDAQGTLSKIFKLGGRDSRS
- Conjugate: PE
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PE-DRB1*04:01/Human MBP (VDAQGTLSKIFKLGGRDSRS) MHC Tetramer (MHC-LC2120)
- Class: Class II
- Antigen: MBP
- Antigen Species: Human
- Peptide: VDAQGTLSKIFKLGGRDSRS
- Conjugate: PE
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PE-DRB1*07:01/Human MBP (VDAQGTLSKIFKLGGRDSRS) MHC Tetramer (MHC-LC2121)
- Class: Class II
- Antigen: MBP
- Antigen Species: Human
- Peptide: VDAQGTLSKIFKLGGRDSRS
- Conjugate: PE
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PE-DRB1*11:01/Human MBP (VDAQGTLSKIFKLGGRDSRS) MHC Tetramer (MHC-LC2122)
- Class: Class II
- Antigen: MBP
- Antigen Species: Human
- Peptide: VDAQGTLSKIFKLGGRDSRS
- Conjugate: PE
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PE-DRB3*01:01/Human MBP (VDAQGTLSKIFKLGGRDSRS) MHC Tetramer (MHC-LC2123)
- Class: Class II
- Antigen: MBP
- Antigen Species: Human
- Peptide: VDAQGTLSKIFKLGGRDSRS
- Conjugate: PE
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PE-H2-IEk/Human MBP (GRTQDENPVVHFFKNIVTPRTPPP) MHC Tetramer (MHC-LC2129)
- Class: Class II
- Antigen: MBP
- Antigen Species: Human
- Peptide: GRTQDENPVVHFFKNIVTPRTPPP
- Conjugate: PE
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PE-DRB1*03:01/Human MBP (KIFKLGGRDSRSGSPMARR) MHC Tetramer (MHC-LC3378)
- Class: Class II
- Antigen: MBP
- Antigen Species: Human
- Peptide: KIFKLGGRDSRSGSPMARR
- Conjugate: PE
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PE-DRB1*03:03/Human MBP (KIFKLGGRDSRSGSPMARR) MHC Tetramer (MHC-LC3379)
- Class: Class II
- Antigen: MBP
- Antigen Species: Human
- Peptide: KIFKLGGRDSRSGSPMARR
- Conjugate: PE
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PE-DRB1*03:05/Human MBP (KIFKLGGRDSRSGSPMARR) MHC Tetramer (MHC-LC3393)
- Class: Class II
- Antigen: MBP
- Antigen Species: Human
- Peptide: KIFKLGGRDSRSGSPMARR
- Conjugate: PE
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PE-DRB1*03:02/Human MBP (KIFKLGGRDSRSGSPMARR) MHC Tetramer (MHC-LC3394)
- Class: Class II
- Antigen: MBP
- Antigen Species: Human
- Peptide: KIFKLGGRDSRSGSPMARR
- Conjugate: PE
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PE-DRB1*01:01/Human MBP (KIFKLGGRDSRSGS) MHC Tetramer (MHC-LC3397)
- Class: Class II
- Antigen: MBP
- Antigen Species: Human
- Peptide: KIFKLGGRDSRSGS
- Conjugate: PE
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PE-DRB5*01:01/Human MBP (KIFKLGGRDSRSGS) MHC Tetramer (MHC-LC3398)
- Class: Class II
- Antigen: MBP
- Antigen Species: Human
- Peptide: KIFKLGGRDSRSGS
- Conjugate: PE
Compare

PE-DRB1*03:03/Human MBP (KIFKLGGRDSRSGS) MHC Tetramer (MHC-LC3399)
- Class: Class II
- Antigen: MBP
- Antigen Species: Human
- Peptide: KIFKLGGRDSRSGS
- Conjugate: PE
Compare

PE-DRB1*01:02/Human MBP (KIFKLGGRDSRSGS) MHC Tetramer (MHC-LC3400)
- Class: Class II
- Antigen: MBP
- Antigen Species: Human
- Peptide: KIFKLGGRDSRSGS
- Conjugate: PE
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PE-DRB1*03:02/Human MBP (KIFKLGGRDSRSGS) MHC Tetramer (MHC-LC3401)
- Class: Class II
- Antigen: MBP
- Antigen Species: Human
- Peptide: KIFKLGGRDSRSGS
- Conjugate: PE
Compare

PE-DRB1*03:01/Human MBP (KIFKLGGRDSRSGS) MHC Tetramer (MHC-LC3402)
- Class: Class II
- Antigen: MBP
- Antigen Species: Human
- Peptide: KIFKLGGRDSRSGS
- Conjugate: PE
Compare

Recombinant Mouse Anti-MBP (GGRASDYKSAH) Soluble TCR (clone 1.D9.B2) (scTCR-188CQ-S(P))
- Species Reactivity: Human
- Epitope: GGRASDYKSAH
- MHC: I-Au
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Recombinant Mouse Anti-MBP Soluble TCR (clone 1.D9.B2) (scTCR-189CQ-S(P))
- Species Reactivity: Human
- Epitope: KGFKGAYDAQG
- MHC: I-Au
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Recombinant Mouse Anti-MBP Soluble TCR (scTCR-190CQ-S(P)) (scTCR-190CQ-S(P))
- Species Reactivity: Human
- Epitope: SRGGASQYRPSQ
- MHC: I-Au
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Recombinant Human Anti-MBP Soluble TCR (clone 3A6) (scTCR-191CQ-S(P))
- Species Reactivity: Human
- Epitope: VHFFKNIVTPRTP
- MHC: HLA-DR2a
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Recombinant Human Anti-MBP Soluble TCR (scTCR-192CQ-S(P)) (scTCR-192CQ-S(P))
- Species Reactivity: Human
- Epitope: ENPVVHFFKNIVTPR
- MHC: HLA-DQ1
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Recombinant Human Anti-MBP Soluble TCR (clone Hy.1F9) (scTCR-193CQ-S(P))
- Species Reactivity: Human
- Epitope: aa 84-102
- MHC: HLA-DR2
Compare

Mouse Anti-MBP Recombinant Antibody (clone 845D3) (FAMAB-0216CQ)
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: ELISA, WB, IB
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Mouse Anti-MBP Recombinant Antibody (clone 34D11) (MOB-1126z)
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, FuncS
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Recombinant Mouse anti-Human MBP Monoclonal antibody (33) (MOB-1267CT)
- Species Reactivity: Human
- Application: IHC-Fr, IHC-P
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Mouse Anti-MBP Recombinant Antibody (clone 845D3); Fab Fragment (FAMAB-0216CQ-F(E))
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, WB
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Mouse Anti-MBP Recombinant Antibody (clone IN-1); scFv Fragment (FAMAB-0107-CN-S(P))
- Derivation: Mouse
- Species Reactivity: Rat
- Type: Mouse scFv
- Application: WB, IF, IP, Block
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Recombinant Human Anti-MBP Antibody scFv Fragment (E2) (FAMAB-0217-CN-S(P))
- Derivation: Phage display library
- Species Reactivity: Human, EBV
- Type: Human scFv
- Application: WB, ELISA, IP
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Recombinant Human Anti-MBP Antibody scFv Fragment (F11) (FAMAB-0218-CN-S(P))
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human scFv
- Application: WB, ELISA, IP
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Recombinant Human Anti-MBP Antibody scFv Fragment (E6) (FAMAB-0219-CN-S(P))
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human scFv
- Application: WB, ELISA, IP
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Mouse Anti-MBP Recombinant Antibody (clone IN-1); Fab Fragment (FAMAB-0107-CN-F(E))
- Derivation: Mouse
- Species Reactivity: Rat
- Type: Mouse Fab
- Application: WB, IF, IP, Block
Compare

Recombinant Human Anti-MBP Antibody scFv Fragment (D1) (FAMAB-0220-CN-S(P))
- Derivation: Phage display library
- Species Reactivity: EBV
- Type: Human scFv
- Application: WB, ELISA, IP
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Recombinant Human Anti-MBP Antibody scFv Fragment (B5V6) (FAMAB-0221-CN-S(P))
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human scFv
- Application: WB, ELISA, IP
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Mouse Anti-MBP Recombinant Antibody (clone 845D3); scFv Fragment (FAMAB-0216CQ-S(P))
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, WB
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Recombinant Human Anti-MBP Antibody Fab Fragment (E2) (FAMAB-0217-CN-F(E))
- Derivation: Phage display library
- Species Reactivity: Human, EBV
- Type: Human Fab
- Application: WB, ELISA, IP
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Hi-Affi™ Recombinant Rabbit Anti-MBP Monoclonal Antibody (DS2184AB) (MOR-2184)
- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: IHC-FoFr, IHC-P
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Chicken Anti-MBP Polyclonal IgY (BRD-0807MZ)
- Species Reactivity: Bovine, Human, Mouse, Rat
- Type: Chicken antibody
- Application: ICC, IF, IHC, WB
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Recombinant Anti-MBP Antibody (Non-glycosylated) (Gly-174LC)
- Host Species: Mouse
- Type: Mouse antibody
- Classification: Non-glycosylated
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For Research Use Only. Not For Clinical Use.

Background

The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases.

Related Diseases

Asthma