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    Mouse Anti-MCL1 Recombinant Antibody (clone 8C6D4B1) (CAT#: VS7-0425-WR367)

    This product is a mouse IgG1 antibody that binds to human MCL-1. The antibody can be used for WB, IHC, and ICC assays.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

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    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
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    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line U-2 OS
    Figure 1 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to mitochondria.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/8455/if_selected.jpg
    Normal Tissue
    Figure 2 Appendix
    Figure 2 Appendix
    (High expression in appendix)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/8455/22739_A_1_2_val_selected.jpg
    Figure 3 IHC staining of human stomach
    Figure 3 IHC staining of human stomach
    (Immunohistochemical staining of human stomach shows strong cytoplasmic positivity in parietal cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/31125/65497_A_3_1_selected.jpg
    Figure 4 IHC staining of human placenta
    Figure 4 IHC staining of human placenta
    (Immunohistochemical staining of human placenta shows strong positivity in trophoblastic cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/68195/ihc_selected.jpg
    Figure 5 Colon
    Figure 5 Colon
    (Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/31125/65497_A_7_3.jpg
    Figure 6 Testis
    Figure 6 Testis
    (Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/31125/65497_A_6_6.jpg
    Figure 7 Thyroid gland
    Figure 7 Thyroid gland
    (Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/31125/65497_B_3_5.jpg
    RNA Expression
    Figure 8 RNA cell line category: Cell line enriched (U-698)
    Figure 8 RNA cell line category: Cell line enriched (U-698)
    (Cell lines ordered by descending RNA expression order)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000143384-MCL1

    Specifications

    • Immunogen
    • Recombinant human MCL-1 fragment expressed in E. Coli.
    • Host Species
    • Mouse
    • Type
    • Mouse IgG1
    • Specificity
    • Human MCL-1
    • Species Reactivity
    • Human
    • Clone
    • 8C6D4B1
    • Molecule Class
    • Anti-Apoptotic Protein
    • Applications
    • WB, IHC, ICC
    • Conjugate
    • Unconjugated

    Product Property

    • Clonality
    • Monoclonal
    • Purity
    • >95% as determined by SDS-PAGE and SEC-HPLC analysis
    • Format
    • Liquid
    • Concentration
    • Please refer to the vial label for the specific concentration.
    • Buffer
    • PBS
    • Preservative
    • 0.03% sodium azide
    • Storage
    • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
    • Shipping
    • Ice packs

    Applications

    • Application Notes
    • Western Blot: 1:500 - 1:2000
      Immunohistochemistry-Paraffin: 1:200 - 1:1000
      Immunocytochemistry: 1:200 - 1:1000
      Enzyme-linked Immunosorbent Assay: 1:10000

    Target

    • Alternative Names
    • MCL1; MCL1L; MCL1-ES; Bcl2-L-3; Myeloid Cell Leukemia 1; Mcl-1; Bcl-2-Like Protein 3; BCL2L3; Myeloid Cell Leukemia Sequence 1 (BCL2-Related); EAT; Myeloid Cell Leukemia ES; Bcl-2-Related Protein EAT/Mcl1; TM; Mcl1/EAT
    • Long Name
    • MCL1, BCL2 Family Apoptosis Regulator
    • Cellular Localization
    • Cytoplasm; Membrane; Mitochondrion; Nucleus
    • Post Translation Modifications
    • Isopeptide bond; Phosphoprotein; Ubl conjugation
    • Function
    • Developmental protein

    Recommended Products

    Isotype Control

    Secondary Antibody

    Reconstitution Buffer

    Recommended Dilution Buffer

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "MCL1"

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    CAT Product Name Application Type
    MOB-1225CT Recombinant Mouse anti-Human MCL1 Monoclonal antibody (49H4) IHC-P
    MRO-0971-CN Recombinant Rabbit Anti-MCL1 Monoclonal Antibody (CBACN-355) WB, IF, IHC, IP, FC Rabbit IgG
    PABS-0143 Human Anti-MCL1 Recombinant Antibody (Clone 01JF43) ELISA, FuncS Human IgG
    ZG-0272C Mouse Anti-MCL1 Recombinant Antibody (ZG-0272C) WB, IHC, IF, ELISA Mouse IgG
    VS3-FY906 Recombinant Rabbit Anti-MCL1 Antibody (clone R04-3A4) WB, ICC, IF, IP Rabbit IgG

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