Mouse Anti-MUC16 Recombinant Antibody (VS3-FY2811)
CAT#: VS3-FY2811
The anti-MUC16 antibody is a mouse IgG recombinant monoclonal antibody. It has been specifically designed to target the human MUC16 protein. The calculated molecular weight of the protein is about 1519 kDa. It is recommended for detection of target protein by Flow cytometry (1/50-1/200) and ELISA (1/1000-1/10000).
Gene Expression
Normal Tissue
Figure 1 Cervix
Glandular cells
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/65600/166228_B_7_3.jpg
RNA Expression
Figure 2 RNA cell line category: Group enriched (A-431, HeLa)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000181143-MUC16
❮
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Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human MUC16
- Species Reactivity
- Human
- Applications
- Flow cytometry, ELISA
- Conjugate
- Unconjugated, FITC
- MW
- The molecular weight of the target protein is approximately 1519 kDa.
- Related Disease
- Clear Cell Adenocarcinoma and Serous Cystadenocarcinoma
Product Property
- Clonality
- Monoclonal Antibody
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Flow cytometry: 1/50-1/200
ELISA: 1/1000-1/10000
Target
- Alternative Names
- Mucin 16, Cell Surface Associated; Ovarian Cancer-Related Tumor Marker CA125; Ovarian Carcinoma Antigen CA125; CA125; CA125 Ovarian Cancer Antigen; Mucin-16; CA-125; MUC-16
- Gene ID
- 94025
- UniProt ID
- Q8WXI7
- Cellular Localization
- Cell membrane
Single-pass type I membrane protein
Secreted, extracellular space
- Post Translation Modifications
- Heavily O-glycosylated; expresses both type 1 and type 2 core glycans. (Q8WXI7-MUC16_HUMAN)
Heavily N-glycosylated; expresses primarily high mannose and complex bisecting type N-linked glycans. (Q8WXI7-MUC16_HUMAN)
May be phosphorylated.
Phosphorylation of the intracellular C-terminal domain may induce proteolytic cleavage and the liberation of the extracellular domain into the extracellular space.
- Protein Refseq
- NP_001401615.1; NP_001401616.1; NP_078966.2
- Function
- Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-H63 | Humanized Anti-MUC16 Recombinant V-kappa Antibody (TAB-H63) | IF, IP, Neut, FuncS, ELISA, FC, WB | Humanized IgG1, κ |
| TAB-0339CL-S(P) | Human Anti-MUC16 Recombinant Antibody; scFv Fragment (TAB-0339CL-S(P)) | DB, WB, IP, ELISA, FC | Humanized scFv |
| TAB-1397CL-S(P) | Human Anti-MUC16 Recombinant Antibody; scFv Fragment (TAB-1397CL-S(P)) | FuncS | Humanized scFv |
| TAB-1399CL-S(P) | Human Anti-MUC16 Recombinant Antibody; scFv Fragment (TAB-1399CL-S(P)) | FuncS | Humanized scFv |
| TAB-0339CL-F(E) | Human Anti-MUC16 Recombinant Antibody; Fab Fragment (TAB-0339CL-F(E)) | DB, WB, IP, ELISA, FC | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-114 | Anti-Human CA-125 Recombinant Antibody (TAB-114) | IP, IF, FuncS, FC, Neut, ELISA, ICC | IgG1 - kappa |
| TAB-1401CL | Anti-Human MUC16 Recombinant Antibody (OC125) | IF, IHC, IP, FC | |
| TAB-1402CL | Anti-Human MUC16 Recombinant Antibody (VK-8) | IF, FC | |
| TAB-1401CL-S(P) | Anti-Human MUC16 Recombinant Antibody scFv Fragment (OC125) | IF, IHC, IP, FC | |
| TAB-1402CL-S(P) | Anti-Human MUC16 Recombinant Antibody scFv Fragment (VK-8) | IF, FC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1398CL | Human Anti-MUC16 Recombinant Antibody (TAB-1398CL) | FuncS | Chimeric (mouse/human) IgG |
| TAB-1400CL | Human Anti-MUC16 Recombinant Antibody (TAB-1400CL) | FuncS | Chimeric (mouse/human) IgG |
| TAB-1398CL-S(P) | Mouse Anti-MUC16 Recombinant Antibody; scFv Fragment (TAB-1398CL-S(P)) | FuncS | Mouse scFv |
| TAB-1400CL-S(P) | Mouse Anti-MUC16 Recombinant Antibody; scFv Fragment (TAB-1400CL-S(P)) | FuncS | Mouse scFv |
| TAB-1398CL-F(E) | Human Anti-MUC16 Recombinant Antibody; Fab Fragment (TAB-1398CL-F(E)) | FuncS | Chimeric (mouse/human) Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2321 | Hi-Affi™ Recombinant Rabbit Anti-MUC16 Monoclonal Antibody (DS2321AB) | ICC, IHC-P, WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0310-YC-F(E) | Mouse Anti-MUC16 Recombinant Antibody; Fab Fragment (HPAB-0310-YC-F(E)) | ELISA, FC, IHC, FuncS | Mouse Fab |
| HPAB-1114LY-F(E) | Mouse Anti-MUC16 Recombinant Antibody; Fab Fragment (HPAB-1114LY-F(E)) | ELISA | Mouse Fab |
| HPAB-0120LY-F(E) | Mouse Anti-MUC16 Recombinant Antibody; Fab Fragment (HPAB-0120LY-F(E)) | WB, ELISA, FC, IHC | Mouse Fab |
| HPAB-0121LY-F(E) | Mouse Anti-MUC16 Recombinant Antibody; Fab Fragment (HPAB-0121LY-F(E)) | WB, ELISA, FC, IHC | Mouse Fab |
| HPAB-0122LY-F(E) | Mouse Anti-MUC16 Recombinant Antibody; Fab Fragment (HPAB-0122LY-F(E)) | WB, ELISA, FC, IHC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1114LY-S(P) | Mouse Anti-MUC16 Recombinant Antibody; scFv Fragment (HPAB-1114LY-S(P)) | ELISA | Mouse scfv |
| HPAB-1115LY-S(P) | Mouse Anti-MUC16 Recombinant Antibody; scFv Fragment (HPAB-1115LY-S(P)) | ELISA | Mouse scfv |
| HPAB-1116LY-S(P) | Mouse Anti-MUC16 Recombinant Antibody; scFv Fragment (HPAB-1116LY-S(P)) | ELISA | Mouse scfv |
| HPAB-1117LY-S(P) | Mouse Anti-MUC16 Recombinant Antibody; scFv Fragment (HPAB-1117LY-S(P)) | ELISA | Mouse scfv |
| HPAB-0120LY-S(P) | Mouse Anti-MUC16 Recombinant Antibody; scFv Fragment (HPAB-0120LY-S(P)) | WB, ELISA, FC, IHC | Mouse scfv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-114 | Afuco™ Anti-MUC16 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-114) | IP, IF, FuncS, FC, Neut, ELISA | ADCC enhanced antibody |
| AFC-TAB-H63 | Afuco™ Anti-MUC16 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-H63) | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0185-YC | Human Anti-MUC16 Recombinant Antibody (HPAB-N0185-YC) | FuncS | Humanized IgG |
| VS3-XY1123 | Mouse Anti-MUC16 Recombinant Antibody (clone CA009) | IHC, WB | Mouse IgG |
| VS3-WK1075 | Mouse Anti-MUC16 Recombinant Antibody (VS3-WK1075) | IHC | Mouse IgG1 |
| VS3-WK1076 | Mouse Anti-MUC16 Recombinant Antibody (clone CA-125) | IHC | Mouse IgG |
| VS13-YC749 | Rabbit Anti-MUC16 Recombinant Antibody (VS13-YC749) | WB, IF | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0924-YC140 | Human Anti-MUC16 Recombinant Antibody Hexamer (VS-0924-YC140), CDC Enhanced | DB, WB, IP, ELISA, FC, CDC | Antibody hexamer |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY70 | Mouse Anti-MUC16 (clone VK-8) scFv-Fc Chimera | IF, FC | Mouse IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC337 | Recombinant Anti-MUC16 Vesicular Antibody, EV Displayed (VS-0425-YC337) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4578 | Anti-MUC16 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-YC133 | Recombinant Anti-MUC16 Biparatopic Antibody, Tandem scFv | ELISA, FC, IHC, WB | Tandem scFv |
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