Mouse Anti-MUC16 Recombinant Antibody (VS3-FY2811) (CAT#: VS3-FY2811)
The anti-MUC16 antibody is a mouse IgG recombinant monoclonal antibody. It has been specifically designed to target the human MUC16 protein. The calculated molecular weight of the protein is about 1519 kDa. It is recommended for detection of target protein by Flow cytometry (1/50-1/200) and ELISA (1/1000-1/10000).
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Normal Tissue
RNA Expression
Figure 1 Cervix
(Glandular cells
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/65600/166228_B_7_3.jpg
(Glandular cells
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/65600/166228_B_7_3.jpg
Figure 2 RNA cell line category: Group enriched (A-431, HeLa)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000181143-MUC16
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000181143-MUC16
Figure 2 RNA cell line category: Group enriched (A-431, HeLa)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000181143-MUC16
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000181143-MUC16
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human MUC16
- Species Reactivity
- Human
- Applications
- Flow cytometry, ELISA
- Conjugate
- Unconjugated, FITC
- MW
- The molecular weight of the target protein is approximately 1519 kDa.
- Related Disease
- Clear Cell Adenocarcinoma and Serous Cystadenocarcinoma
Product Property
- Clonality
- Monoclonal Antibody
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Flow cytometry: 1/50-1/200
ELISA: 1/1000-1/10000
Target
- Alternative Names
- Mucin 16, Cell Surface Associated; Ovarian Cancer-Related Tumor Marker CA125; Ovarian Carcinoma Antigen CA125; CA125; CA125 Ovarian Cancer Antigen; Mucin-16; CA-125; MUC-16
- Gene ID
- 94025
- UniProt ID
- Q8WXI7
- Cellular Localization
- Cell membrane
Single-pass type I membrane protein
Secreted, extracellular space
- Post Translation Modifications
- Heavily O-glycosylated; expresses both type 1 and type 2 core glycans. (Q8WXI7-MUC16_HUMAN)
Heavily N-glycosylated; expresses primarily high mannose and complex bisecting type N-linked glycans. (Q8WXI7-MUC16_HUMAN)
May be phosphorylated.
Phosphorylation of the intracellular C-terminal domain may induce proteolytic cleavage and the liberation of the extracellular domain into the extracellular space.
- Protein Refseq
- NP_001401615.1; NP_001401616.1; NP_078966.2
- Function
- Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces.
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-H63 | Humanized Anti-MUC16 Recombinant V-kappa Antibody (TAB-H63) | IF, IP, Neut, FuncS, ELISA, FC, WB | Humanized IgG1, κ |
| TAB-1397CL | Human Anti-MUC16 Recombinant Antibody (TAB-1397CL) | FuncS | Humanized IgG |
| TAB-1397CL-S(P) | Human Anti-MUC16 Recombinant Antibody; scFv Fragment (TAB-1397CL-S(P)) | FuncS | Humanized scFv |
| TAB-1399CL-S(P) | Human Anti-MUC16 Recombinant Antibody; scFv Fragment (TAB-1399CL-S(P)) | FuncS | Humanized scFv |
| TAB-0339CL-F(E) | Human Anti-MUC16 Recombinant Antibody; Fab Fragment (TAB-0339CL-F(E)) | DB, WB, IP, ELISA, FC | Humanized Fab |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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