Anti-MUC16 Recombinant Antibody Products

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Anti-MUC16 Products

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For Research Use Only. Not For Clinical Use.

Creative Biolabs focuses on supplying top-notch anti-MUC16 antibodies for biomedical research. Understanding the importance of accurate antibodies, we maintain high quality and reliability. Our dedication enables researchers to obtain reliable tools for breakthroughs.

MUC16: A Significant Target for Cancer Diagnosis and Therapy

MUC16 (Mucin 16) is a transmembrane glycoprotein and a member of the mucin family, primarily known as the biomarker CA125. It plays a crucial role in cell adhesion, immune evasion, and tumor progression, particularly in ovarian, pancreatic, and other epithelial cancers. Overexpression of MUC16 is associated with cancer metastasis, chemotherapy resistance, and immune modulation, making it a significant target for cancer diagnosis and therapy. Researchers are actively exploring MUC16-targeted therapies, including monoclonal antibodies, CAR-T cells, and antibody-drug conjugates, to improve treatment outcomes.

Alternative Names

CA125

Background

This gene encodes a protein that is a member of the mucin family. Mucins are high molecular weight, O-glycosylated proteins that play an important role in forming a protective mucous barrier, and are found on the apical surfaces of the epithelia. The encoded protein is a membrane-tethered mucin that contains an extracellular domain at its amino terminus, a large tandem repeat domain, and a transmembrane domain with a short cytoplasmic domain. The amino terminus is highly glycosylated, while the repeat region contains 156 amino acid repeats unit that are rich in serines, threonines, and prolines. Interspersed within the repeats are Sea urchin sperm protein Enterokinase and Agrin (SEA) modules, leucine-rich repeats and ankyrin (ANK) repeats. These regions together form the ectodomain, and there is a potential cleavage site found near an SEA module close to the transmembrane domain. This protein is thought to play a role in forming a barrier, protecting epithelial cells from pathogens. Products of this gene have been used as a marker for different cancers, with higher expression levels associated with poorer outcomes.

Anti-MUC16 rAb Products

At Creative Biolabs, we strive to offer premium anti - MUC16 recombinant antibodies for target - based drug research. By providing reliable, high - performing products, we're dedicated to fueling scientific advancement and helping researchers in their discovery work.

Creative Quality Control

Our team uses advanced tech and strict quality checks to create outstanding antibody products. We focus on excellence for reliable, precise results. Our high - performance anti - MUC16 antibodies support scientific growth, aiding in the development of better therapies and boosting biomedical research and drug discovery.

Customer Reviews

Excellent

E**ly
Anti-Human MUC16 Recombinant Antibody (VK-8) (Cat#: TAB-1402CL)

The antibody is a crucial tool for MUC16 research. MUC16 is a significant cancer biomarker. Suitable for immunofluorescence and flow cytometry, this antibody accurately detects MUC16 expression in cells. With high specificity and recombinant production, it guarantees consistent and reliable experimental outcomes, making it ideal for cancer research, biomarker analysis, and related studies.

23/May/2024

Excellent

Ja**s
Anti-Human MUC16 Recombinant Antibody (OC125) (Cat#: TAB-1401CL)

This antibody is a reliable option for detecting MUC16, a key cancer biomarker. Applicable in IF, IHC, IP, and FC, it provides versatility for diverse experiments. Its high specificity enables accurate MUC16 detection in samples, making it perfect for consistent and reproducible research on cancer progression and biomarker expression.

10/Sep/2023

Excellent

Nic**las
Mouse Anti-MUC16 Recombinant Antibody (Cat#: HPAB-0122LY)

The antibody is a highly specific and reliable tool for detecting MUC16, a key biomarker in cancer research. Validated for WB, ELISA, FC, and IHC, it offers versatility in various assays. Produced recombinantly, it ensures consistent performance across batches, making it an excellent choice for studying MUC16 expression, disease progression, and therapeutic targets in oncology and related biomedical research.

18/Aug/2022

rAb Production

Leveraging our in - depth knowledge in expression vector optimization, transfected cell line selection, and antibody purification, we offer comprehensive end - to - end services. Starting from gene synthesis to antibody production, our expertise streamlines workflows for high - yield antibody generation. By incorporating advanced screening and purification methods, we provide customized, top - notch solutions for various research requirements, facilitating more reliable and efficient scientific outcomes.

Featured Anti-MUC16 Recombinant Antibody Production Platforms
Fig.3 Milligram-scale recombinant antibody production.

Fig.4 Gram-scale recombinant antibody production.

rAb Modalities

Creative Biolabs is a leader in providing diverse recombinant antibody formats tailored to research, spanning basic science to drug discovery. We meticulously engineer our antibodies for outstanding quality, reliability, and performance, catering to researchers' distinct needs. Our focus on versatility and innovation aims to speed up scientific progress and biomedical leaps. By enhancing our tech and growing our product line, we arm researchers for therapeutic and advanced research success.

Fig.5 Full Length Anti-MUC16 Recombinant Antibody Production and Modalities.

Drug Information Targeting MUC16

Table 1. Therapeutic approaches targeting MUC16 in clinical development.

If you want details about our anti - MUC16 recombinant antibody products or have any questions, don't hesitate to contact us. Our expert team is eager to offer customized support and professional advice. We're committed to ensuring a seamless experience, providing dependable solutions to help you reach significant scientific achievements. We're here for your success.