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MUC16

Anti-MUC16 Recombinant Antibody Products
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- Species Reactivity: Human
- Type: Antibody hexamer
- Application: DB, WB, IP, ELISA, FC, CDC
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG
- Application: IHC-P, IF
- Anti-Human MUC16 Recombinant Antibody (VK-8) (TAB-1402CL)
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- Application: IF, FC
- Human Anti-MUC16 Recombinant Antibody; scFv Fragment (TAB-0339CL-S(P)) (TAB-0339CL-S(P))
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- Species Reactivity: Human
- Type: Humanized scFv
- Application: DB, WB, IP, ELISA, FC
- Human Anti-MUC16 Recombinant Antibody; scFv Fragment (TAB-1397CL-S(P)) (TAB-1397CL-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: FuncS
- Human Anti-MUC16 Recombinant Antibody; Fab Fragment (TAB-0339CL-F(E)) (TAB-0339CL-F(E))
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- Species Reactivity: Human
- Type: Humanized Fab
- Application: DB, WB, IP, ELISA, FC
- Human Anti-MUC16 Recombinant Antibody (TAB-1399CL) (TAB-1399CL)
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- Species Reactivity: Human
- Type: Humanized IgG
- Application: FuncS
- Human Anti-MUC16 Recombinant Antibody (TAB-1400CL) (TAB-1400CL)
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- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG
- Application: FuncS
- Mouse Anti-MUC16 Recombinant Antibody (clone 196-14) (FAMAB-0043YC)
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- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: FuncS
- Human Anti-MUC16 Recombinant Antibody; Fab Fragment (TAB-1397CL-F(E)) (TAB-1397CL-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: FuncS
- Human Anti-MUC16 Recombinant Antibody; Fab Fragment (TAB-1398CL-F(E)) (TAB-1398CL-F(E))
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- Species Reactivity: Human
- Type: Chimeric (mouse/human) Fab
- Application: FuncS
- Human Anti-MUC16 Recombinant Antibody; Fab Fragment (TAB-1399CL-F(E)) (TAB-1399CL-F(E))
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- Species Reactivity: Human
- Type: Humanized Fab
- Application: FuncS
- Human Anti-MUC16 Recombinant Antibody; Fab Fragment (TAB-1400CL-F(E)) (TAB-1400CL-F(E))
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- Species Reactivity: Human
- Type: Chimeric (mouse/human) Fab
- Application: FuncS
- Mouse Anti-MUC16 Recombinant Antibody; scFv Fragment (TAB-1398CL-S(P)) (TAB-1398CL-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: FuncS
- Human Anti-MUC16 Recombinant Antibody; scFv Fragment (TAB-1399CL-S(P)) (TAB-1399CL-S(P))
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- Species Reactivity: Human
- Type: Humanized scFv
- Application: FuncS
- Mouse Anti-MUC16 Recombinant Antibody; scFv Fragment (TAB-1400CL-S(P)) (TAB-1400CL-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: FuncS
- Mouse Anti-MUC16 Recombinant Antibody (HPAB-1114LY) (HPAB-1114LY)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA
- Mouse Anti-MUC16 Recombinant Antibody (HPAB-1115LY) (HPAB-1115LY)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA
- Mouse Anti-MUC16 Recombinant Antibody (HPAB-1116LY) (HPAB-1116LY)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA
- Mouse Anti-MUC16 Recombinant Antibody (HPAB-1117LY) (HPAB-1117LY)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA
- Mouse Anti-MUC16 Recombinant Antibody (HPAB-0121LY) (HPAB-0121LY)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, ELISA, FC, IHC
- Mouse Anti-MUC16 Recombinant Antibody (HPAB-0122LY) (HPAB-0122LY)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, ELISA, FC, IHC
- Human Anti-MUC16 Recombinant Antibody (clone ch196-14) (FAMAB-0044YC)
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG
- Application: FuncS
- Mouse Anti-MUC16 Recombinant Antibody (HPAB-0120LY) (HPAB-0120LY)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, ELISA, FC, IHC
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: IHC
- Mouse Anti-MUC16 Recombinant Antibody (HPAB-0310-YC) (HPAB-0310-YC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, FC, IHC, FuncS
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG
- Application: IHC-P, IF
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA, IHC
- Rabbit Anti-MUC16 Recombinant Antibody (VS3-WK1079) (VS3-WK1079)
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- Derivation: Rabbit
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, ICC, IF, FC
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- Type: Mouse IgG1
- Application: ELISA, IHC, FC
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- Type: Mouse IgG1
- Application: ELISA, IHC, FC
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: IHC-P
- Mouse Anti-MUC16 Recombinant Antibody (VS3-FY2811) (VS3-FY2811)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: FC, ELISA
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IF, FC
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IF, FC
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- Derivation: Mouse
- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Application: IP, IF, FuncS, FC, Neut, ELISA
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- Derivation: Humanized
- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Application: IF, IP, Neut, FuncS, ELISA, FC
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA, IHC
- Mouse Anti-MUC16 Recombinant Antibody (clone CA009) (VS3-XY1123)
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- Type: Mouse IgG
- Application: IHC, WB
- Mouse Anti-MUC16 Recombinant Antibody (VS3-WK1075) (VS3-WK1075)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: IHC
- Mouse Anti-MUC16 Recombinant Antibody (clone CA-125) (VS3-WK1076)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG
- Application: IHC
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: IHC-P
- Mouse Anti-MUC16 Recombinant Antibody (clone PT1783) (VS3-WK1078)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: IHC-P
- Human Anti-MUC16 Recombinant Antibody (HPAB-N0185-YC) (HPAB-N0185-YC)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: FuncS
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, ELISA, IHC
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG1, κ
- Application: IF, IP, Neut, FuncS, ELISA, FC, WB
- Human Anti-MUC16 Recombinant Antibody (TAB-0339CL) (TAB-0339CL)
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- Species Reactivity: Human
- Type: Humanized Antibody
- Application: DB, WB, IP, ELISA, FC, CDC
- Human Anti-MUC16 Recombinant Antibody (TAB-1397CL) (TAB-1397CL)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: FuncS
- Human Anti-MUC16 Recombinant Antibody (TAB-1398CL) (TAB-1398CL)
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- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG
- Application: FuncS
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
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- Derivation: Mouse
- Species Reactivity: Human
- Type: F(ab')2 - G1
- Application: ELISA, FC, IP, FuncS, IF, Neut, IHC
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- Species Reactivity: Human
- Type: scFv
- Human Anti-MUC16 Recombinant Antibody; scFv Fragment (HPAB-N0185-YC-S(P)) (HPAB-N0185-YC-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: FuncS
- Human Anti-MUC16 Recombinant Antibody; Fab Fragment (HPAB-N0185-YC-F(E)) (HPAB-N0185-YC-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: FuncS
- Mouse Anti-MUC16 Recombinant Antibody; Fab Fragment (HPAB-1116LY-F(E)) (HPAB-1116LY-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
- Mouse Anti-MUC16 Recombinant Antibody; Fab Fragment (HPAB-1117LY-F(E)) (HPAB-1117LY-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
- Mouse Anti-MUC16 Recombinant Antibody; scFv Fragment (HPAB-0120LY-S(P)) (HPAB-0120LY-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse scfv
- Application: WB, ELISA, FC, IHC
- Mouse Anti-MUC16 Recombinant Antibody; scFv Fragment (HPAB-0121LY-S(P)) (HPAB-0121LY-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse scfv
- Application: WB, ELISA, FC, IHC
- Mouse Anti-MUC16 Recombinant Antibody; scFv Fragment (HPAB-0122LY-S(P)) (HPAB-0122LY-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse scfv
- Application: WB, ELISA, FC, IHC
- Mouse Anti-MUC16 Recombinant Antibody; Fab Fragment (HPAB-0120LY-F(E)) (HPAB-0120LY-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse Fab
- Application: WB, ELISA, FC, IHC
- Mouse Anti-MUC16 Recombinant Antibody; Fab Fragment (HPAB-0121LY-F(E)) (HPAB-0121LY-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse Fab
- Application: WB, ELISA, FC, IHC
- Mouse Anti-MUC16 Recombinant Antibody; Fab Fragment (HPAB-0122LY-F(E)) (HPAB-0122LY-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse Fab
- Application: WB, ELISA, FC, IHC
- Mouse Anti-MUC16 Recombinant Antibody; scFv Fragment (HPAB-0310-YC-S(P)) (HPAB-0310-YC-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, FC, IHC, FuncS
- Mouse Anti-MUC16 Recombinant Antibody; Fab Fragment (HPAB-0310-YC-F(E)) (HPAB-0310-YC-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, FC, IHC, FuncS
- Mouse Anti-MUC16 Recombinant Antibody (clone 196-14); scFv Fragment (FAMAB-0043-YC-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: FuncS
- Mouse Anti-MUC16 Recombinant Antibody (clone ch196-14); scFv Fragment (FAMAB-0044-YC-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: FuncS
- Mouse Anti-MUC16 Recombinant Antibody (clone 196-14); Fab Fragment (FAMAB-0043-YC-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: FuncS
- Human Anti-MUC16 Recombinant Antibody (clone ch196-14); Fab Fragment (FAMAB-0044-YC-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: FuncS
- Mouse Anti-MUC16 Recombinant Antibody; scFv Fragment (HPAB-1114LY-S(P)) (HPAB-1114LY-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse scfv
- Application: ELISA
- Mouse Anti-MUC16 Recombinant Antibody; scFv Fragment (HPAB-1115LY-S(P)) (HPAB-1115LY-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse scfv
- Application: ELISA
- Mouse Anti-MUC16 Recombinant Antibody; scFv Fragment (HPAB-1116LY-S(P)) (HPAB-1116LY-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse scfv
- Application: ELISA
- Mouse Anti-MUC16 Recombinant Antibody; scFv Fragment (HPAB-1117LY-S(P)) (HPAB-1117LY-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse scfv
- Application: ELISA
- Mouse Anti-MUC16 Recombinant Antibody; Fab Fragment (HPAB-1114LY-F(E)) (HPAB-1114LY-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
- Mouse Anti-MUC16 Recombinant Antibody; Fab Fragment (HPAB-1115LY-F(E)) (HPAB-1115LY-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
- Anti-Human MUC16 Recombinant Antibody scFv Fragment (OC125) (TAB-1401CL-S(P))
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- Application: IF, IHC, IP, FC
- Anti-Human MUC16 Recombinant Antibody scFv Fragment (VK-8) (TAB-1402CL-S(P))
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- Application: IF, FC
- Anti-Human MUC16 Recombinant Antibody Fab Fragment (OC125) (TAB-1401CL-F(E))
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- Application: IF, IHC, IP, FC
- Anti-Human MUC16 Recombinant Antibody Fab Fragment (VK-8) (TAB-1402CL-F(E))
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- Application: IF, FC
- Anti-Human MUC16 Recombinant Antibody (OC125) (TAB-1401CL)
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- Application: IF, IHC, IP, FC
- Anti-Mucin 16-vc-MMAE ADC (ADC-123LZY)
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- Target: Mucin 16
- Linker: VC (valine-citrulline)
- Drug: MMAE (monomethyl auristatin E)
- Anti-MUC16 (clone ch11D10)-mc-MMAF ADC (ADC-217LZY)
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- Target: MUC16
- Linker: mc (maleimidocaproyl)
- Drug: MMAF (monomethyl auristatin F)
- Anti-MUC16 (clone ch11D10)-vc-MMAF ADC (ADC-218LZY)
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- Target: MUC16
- Linker: VC (valine-citrulline)
- Drug: MMAF (monomethyl auristatin F)
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: ICC, IHC-P, WB
- Anti-MUC16 (clone 3A5)-MC-vc-PAB-MMAE ADC (ADC-044CL)
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- Target: MUC16
- Linker: MC-VC-PABC (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl)
- Drug: MMAE (Monomethyl auristatin E)
- Rabbit Anti-MUC16 Recombinant Antibody (VS13-YC749) (VS13-YC749)
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IF
- Mouse Anti-MUC16 (clone VK-8) scFv-Fc Chimera (VS-0425-FY70)
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- Species Reactivity: Human
- Type: Mouse IgG1, scFv-Fc
- Application: IF, FC
- Mouse Anti-MUC16 Recombinant Antibody (clone 1E1B9) (VS7-0425-WR438)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: FC
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- Species Reactivity: Human
- Target: MUC16
- Host Animal: Mouse
- Application: ELISA, FC, Neut, Cell-uptake
- Anti-MUC16 (clone 3A5)-MC-vc-PAB-MMAE ADC (ADC-045CL)
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- Target: MUC16
- Linker: MC-VC-PABC (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl)
- Drug: MMAE (Monomethyl auristatin E)
- Anti-MUC16 (clone 3A5)-vc-MMAE ADC (ADC-046CL)
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- Target: MUC16
- Linker: VC (valine-citrulline)
- Drug: MMAE (Monomethyl auristatin E)
- Anti-MUC16 (clone 3A5)-vc-MMAE ADC (ADC-047CL)
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- Target: MUC16
- Linker: VC (valine-citrulline)
- Drug: MMAE (Monomethyl auristatin E)
- Anti-MUC16 (clone 3A5)-BMPEO-DM1 ADC (ADC-188CL)
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- Target: MUC16
- Linker: BMPEO (bis-maleimido-trioxyethylene glycol)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
- Anti-MUC16 (Sofituzumab)-vc-MMAE ADC (ADC-146LCT)
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- Target: MUC16
- Linker: VC (valine-citrulline)
- Drug: MMAE (Monomethyl auristatin E)
- Anti-MUC16-mc-vc-PAB-MMAE ADC (ADC-009LZY)
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- Target: MUC16
- Linker: mc-VC-PAB (proteaselabile maleimido-caproyl-valine-citrulline-para-amino-benzyloxy carbonyl )
- Drug: MMAE (monomethyl auristatin E)
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For Research Use Only. Not For Clinical Use.
This gene encodes a protein that is a member of the mucin family. Mucins are high molecular weight, O-glycosylated proteins that play an important role in forming a protective mucous barrier, and are found on the apical surfaces of the epithelia. The encoded protein is a membrane-tethered mucin that contains an extracellular domain at its amino terminus, a large tandem repeat domain, and a transmembrane domain with a short cytoplasmic domain. The amino terminus is highly glycosylated, while the repeat region contains 156 amino acid repeats unit that are rich in serines, threonines, and prolines. Interspersed within the repeats are Sea urchin sperm protein Enterokinase and Agrin (SEA) modules, leucine-rich repeats and ankyrin (ANK) repeats. These regions together form the ectodomain, and there is a potential cleavage site found near an SEA module close to the transmembrane domain. This protein is thought to play a role in forming a barrier, protecting epithelial cells from pathogens. Products of this gene have been used as a marker for different cancers, with higher expression levels associated with poorer outcomes. [provided by RefSeq, May 2017]
