Rabbit Anti-NGFR Recombinant Antibody (VS13-YC806)
CAT#: VS13-YC806
The Rabbit Anti-NGFR Recombinant Antibody is specific for human, mouse and rat NGFR. NGFR, a nerve growth factor receptor, has extracellular, transmembrane, and cytoplasmic components, with the cysteine-rich area binding nerve growth factors. The anti-NGFR antibody can be used for Western blot (1/500-1/1000), Immunohistochemistry (1/50-1/100), Immunofluorescence (1/50-1/200), Immunoprecipitation (1/50).
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & plasma membrane.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4765/if_selected.jpg
Normal Tissue
Figure 2 Adrenal gland
High expression
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4765/15396_B_6_5_val_selected.jpg
Normal Tissue
Figure 3 Colon
Peripheral nerve/ganglion Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1995/5109_A_9_3.jpg
Normal Tissue
Figure 4 Kidney
Cells in glomeruli Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/143/2551_A_9_5.jpg
RNA Expression
Figure 5 RNA cell line category: Group enriched (RH-30, WM-115)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000064300-NGFR
❮
❯
Specifications
- Immunogen
- Recombinant human p75 NGF receptor.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat NGFR
- Species Reactivity
- Human, Mouse, Rat
- Applications
- WB, IHC-P, ICC, IF, IP
- Conjugate
- NONE
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS (pH 7.4) containing 150 mM NaCl and 50% Glycerol.
- Preservative
- 0.02% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/500-1/1000
Immunohistochemistry (IHC): 1/50-1/100
Immunofluorescence (IF): 1/50-1/200
Immunoprecipitation (IP): 1/50
Target
- Alternative Names
- Nerve Growth Factor Receptor; Low Affinity Neurotrophin Receptor P75NTR; Low-Affinity Nerve Growth Factor Receptor; TNFR Superfamily, Member 16; NGF Receptor; Gp80-LNGFR; TNFRSF16; P75 ICD;
- Gene ID
- 4804
- UniProt ID
- P08138
- Long Name
- Nerve Growth Factor Receptor
- Cellular Localization
- Cell membrane; Cell projection; Membrane; Synapse
- Protein Refseq
- NP_002498.1
- Function
- Low affinity receptor which can bind to NGF, BDNF, NTF3, and NTF4. Forms a heterodimeric receptor with SORCS2 that binds the precursor forms of NGF, BDNF and NTF3 with high affinity, and has much lower affinity for mature NGF and BDNF (PubMed:24908487).
Plays an important role in differentiation and survival of specific neuronal populations during development (By similarity).
Can mediate cell survival as well as cell death of neural cells. Plays a role in the inactivation of RHOA (PubMed:26646181).
Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake (By similarity).
Necessary for the circadian oscillation of the clock genes ARNTL/BMAL1, PER1, PER2 and NR1D1 in the suprachiasmatic nucleus (SCmgetaN) of the brain and in liver and of the genes involved in glucose and lipid metabolism in the liver (PubMed:23785138).
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for VS13-YC806. Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "NGFR"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1958z | Mouse Anti-NGFR Recombinant Antibody (clone 32C5) | WB, FC, ICC, IHC | Mouse IgG1 |
| HPAB-0276CQ | Mouse Anti-NGFR Recombinant Antibody (clone MC192) | ELISA, IHC, IP, IF, WB, FuncS | Mouse IgG1 |
| VS3-QX818 | Mouse Anti-NGFR Recombinant Antibody (clone 2F1C2) | WB, IHC, ICC, FC, ELISA | Mouse IgG1 |
| VS3-XY1166 | Mouse Anti-NGFR Recombinant Antibody (clone 2G2) | WB, IP, IF | Mouse IgG1 |
| VS3-FY1042 | Recombinant Mouse Anti-NGFR Antibody (clone 8G8H10) | ELISA, IHC, FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-L038S | anti-Ngfr immunotoxin MC-192 (IgG)-Sap | Cytotoxicity assay, Functional assay |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1778CQ | Recombinant Mouse Anti-NGFR Antibody (ME20.4) | EM, ELISA, FC, ICC, IF, IHC-P, Inhib, IP, RIA, WB | IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1779CQ | Recombinant Mouse Anti-NGFR Antibody (5H1) | IHC, IP, Neut, WB | IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2440 | Hi-Affi™ Recombinant Rabbit Anti-NGFR Monoclonal Antibody (DS2440AB) | IHC-P | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0276CQ-F(E) | Mouse Anti-NGFR Recombinant Antibody (clone MC192); Fab Fragment | ELISA, IHC, IP, WB | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY203 | AbPlus™ Anti-NGFR Magnetic Beads (MC192) | IP, Protein Purification | |
| VS-0724-YC1307 | AbPlus™ Anti-NGFR Magnetic Beads (VS-0724-YC1307) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY341 | Mouse Anti-NHP NGFR Recombinant Antibody (clone NGFR5) | WB, IF, FC | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC590 | Recombinant Anti-NGFR Vesicular Antibody, EV Displayed (VS-0425-YC590) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4831 | Anti-NGFR Immunohistochemistry Kit | IHC |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
Application: FC, IP, ELISA, Neut, FuncS, IF, WB
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
Application: ELISA, Neut, FuncS
Application: Neut, Inhib, FC, ELISA
Application: Neut, ELISA, FuncS
Application: ELISA, WB, Microarray, Block
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
