Mouse Anti-PDGFB Recombinant Antibody (clone C1); Fab Fragment
CAT#: HPAB-0067-YJ-F(E)
Mab C1 is a mouse Fab binds to human or pig PDGF-BB. PDGF acts as a potent mitogen, chemoattractant and survival factor for mesenchymal cells. PDGF plays a critical role in physiological repair mechanism but also functions in the pathogenesis of various proliferative diseases. Mab C1 acts as a PDGF antagonist. It inhibits the proliferation of several tumor cell lines and human brain tumor cell and inhibits signal transduction by PDGF-BB.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line MCF7
Immunofluorescent staining of human cell line MCF7 shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/11972/1592_D1_1_selected.jpg
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Specifications
- Immunogen
- Recombinant PDGF-BB
- Host Species
- Mouse
- Type
- Mouse Fab
- Specificity
- Human
- Species Reactivity
- Human, Pig
- Clone
- C1
- Applications
- ELISA, FuncS, Apop
- Related Disease
- Cancers, Proliferative diseases
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Platelet Derived Growth Factor Subunit B; Becaplermin; Platelet-Derived Growth Factor Beta Polypeptide (Simian Sarcoma Viral (V-Sis) Oncogene Homolog); Platelet-Derived Growth Factor Beta Polypeptide; Platelet-Derived Growth Factor B Chain; Proto-Oncogene C-Sis; PDGF Subunit B; PDGF-2; PDGF2; SIS; MAb C1
- Gene ID
- 5155
- UniProt ID
- P01127
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone C1"
- CAT
- Product Name
See other products for "PDGFB"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-297 | Human Anti-PDGFB Recombinant Antibody scFv Fragment (PSBL-297) | WB, ELISA, FuncS | Human scFv |
| HPAB-0385-CN-S(P) | Human Anti-PDGFB Recombinant Antibody; scFv Fragment (HPAB-0385-CN-S(P)) | ELISA, FC, IF, Block | Human scFv |
| HPAB-0386-CN-S(P) | Rat Anti-PDGFB Recombinant Antibody; scFv Fragment (HPAB-0386-CN-S(P)) | ELISA, Block | Rat scFv |
| HPAB-0387-CN-S(P) | Rat Anti-PDGFB Recombinant Antibody; scFv Fragment (HPAB-0387-CN-S(P)) | ELISA, Block | Rat scFv |
| HPAB-0388-CN-S(P) | Rat Anti-PDGFB Recombinant Antibody; scFv Fragment (HPAB-0388-CN-S(P)) | ELISA, Block | Rat scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-297 | Human Anti-PDGFB Recombinant Antibody Fab Fragment (PFBL-297) | WB, ELISA, FuncS | Human Fab |
| HPAB-0385-CN-F(E) | Human Anti-PDGFB Recombinant Antibody; Fab Fragment (HPAB-0385-CN-F(E)) | ELISA, FC, IF, Block | Human Fab |
| HPAB-0386-CN-F(E) | Rat Anti-PDGFB Recombinant Antibody; Fab Fragment (HPAB-0386-CN-F(E)) | ELISA, Block | Rat Fab |
| HPAB-0387-CN-F(E) | Rat Anti-PDGFB Recombinant Antibody; Fab Fragment (HPAB-0387-CN-F(E)) | ELISA, Block | Rat Fab |
| HPAB-0388-CN-F(E) | Rat Anti-PDGFB Recombinant Antibody; Fab Fragment (HPAB-0388-CN-F(E)) | ELISA, Block | Rat Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1020CL | Anti-Human PDGFB Recombinant Antibody (F3) | ELISA | Rabbit mAb |
| TAB-1020CL-S(P) | Anti-Human PDGFB Recombinant Antibody scFv Fragment (F3) | ELISA | Rabbit mAb |
| TAB-1020CL-F(E) | Anti-Human PDGFB Recombinant Antibody Fab Fragment (F3) | ELISA | Rabbit mAb |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1021CL | Anti-Human PDGFB Recombinant Antibody (C12) | ELISA | Humanized antibody |
| TAB-1021CL-S(P) | Anti-Human PDGFB Recombinant Antibody scFv Fragment (C12) | ELISA | Humanized antibody |
| TAB-1021CL-F(E) | Anti-Human PDGFB Recombinant Antibody Fab Fragment (C12) | ELISA | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2635 | Hi-Affi™ Recombinant Rabbit Anti-PDGFB Monoclonal Antibody (DS2635AB) | WB, IHC-P | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0385-CN | Human Anti-PDGFB Recombinant Antibody (HPAB-0385-CN) | ELISA, FC, IF, Block | Human IgG |
| HPAB-0386-CN | Rat Anti-PDGFB Recombinant Antibody (HPAB-0386-CN) | ELISA, Block | Rat IgG2b, κ |
| HPAB-0387-CN | Rat Anti-PDGFB Recombinant Antibody (HPAB-0387-CN) | ELISA, Block | Rat IgG2b, λ |
| HPAB-0388-CN | Rat Anti-PDGFB Recombinant Antibody (HPAB-0388-CN) | ELISA, Block | Rat IgG2b, κ |
| HPAB-0389-CN | Human Anti-PDGFB Recombinant Antibody (HPAB-0389-CN) | ELISA, Block | Humanized IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY5273 | Anti-PDGFB Immunohistochemistry Kit | IHC |
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