Mouse Anti-PDGFB Recombinant Antibody (clone C1); Fab Fragment

CAT#: HPAB-0067-YJ-F(E)

Mab C1 is a mouse Fab binds to human or pig PDGF-BB. PDGF acts as a potent mitogen, chemoattractant and survival factor for mesenchymal cells. PDGF plays a critical role in physiological repair mechanism but also functions in the pathogenesis of various proliferative diseases. Mab C1 acts as a PDGF antagonist. It inhibits the proliferation of several tumor cell lines and human brain tumor cell and inhibits signal transduction by PDGF-BB.

Gene Expression
Figure 1 IF staining of human cell line MCF7 Figure 2 IHC staining of human caudate Figure 3 Placenta Figure 4 Lymph node Figure 5 Liver Figure 6 Kidney Figure 7 Testis Figure 8 RNA cell line category: Cell line enhanced (A-431, EFO-21, HUVEC TERT2, SK-BR-3, TIME)

Specifications

  • Immunogen
  • Recombinant PDGF-BB
  • Host Species
  • Mouse
  • Type
  • Mouse Fab
  • Specificity
  • Human
  • Species Reactivity
  • Human, Pig
  • Clone
  • C1
  • Related Disease
  • Cancers, Proliferative diseases

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • Platelet Derived Growth Factor Subunit B; Becaplermin; Platelet-Derived Growth Factor Beta Polypeptide (Simian Sarcoma Viral (V-Sis) Oncogene Homolog); Platelet-Derived Growth Factor Beta Polypeptide; Platelet-Derived Growth Factor B Chain; Proto-Oncogene C-Sis; PDGF Subunit B; PDGF-2; PDGF2; SIS; MAb C1
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Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

MSDS

COA

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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