Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, RAS pathway related proteins
Intracellular, Secreted (different isoforms)
Cell type enhanced (Adipocytes, Endothelial cells, Pancreatic endocrine cells, Langerhans cells, Macrophages)
Immune cell enhanced (MAIT T-cell)
Cell line enhanced (A-431, EFO-21, HUVEC TERT2, SK-BR-3, TIME)
Antiparallel homodimer; disulfide-linked. Antiparallel heterodimer with PDGFA; disulfide-linked. The PDGFB homodimer interacts with PDGFRA and PDGFRB homodimers, and with heterodimers formed by PDGFRA and PDGFRB. The heterodimer composed of PDGFA and PDGFB interacts with PDGFRB homodimers, and with heterodimers formed by PDGFRA and PDGFRB. Interacts with XLKD1 (By similarity). Interacts with LRP1 (PubMed:15053742). Interacts with SORL1 (via the N-terminal ectodomain) (PubMed:15053742, PubMed:16393139).
Developmental protein, Growth factor, Mitogen
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For Research Use Only. Not For Clinical Use.