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  • Mouse Anti-PDGFRB Recombinant Antibody (clone muM4TS.11); Fab Fragment

Mouse Anti-PDGFRB Recombinant Antibody (clone muM4TS.11); Fab Fragment (CAT#: HPAB-S0105-YC-F(E))

Provided is an antibody muM4TS.11 that specific for the platelet-derived growth factor receptor β. muM4TS.11 does not bind to deletion proteins containing only the first through third domains of PDGF-R β, but does bind to protein D1-4 containing the fourth domain, showing that the binding epitope is in the fourth domain. muM4TS.11 effectively inhibited the stimulation of proliferation by PDGF BB, showing the ability of these antibodies to neutralize the biological activity of PDGF BB.


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Specific Inquiry
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Subcellular Location
Figure 1 IF staining of human cell line ASC TERT1
Figure 1 IF staining of human cell line ASC TERT1
(Immunofluorescent staining of human cell line ASC TERT1 shows localization to the Golgi apparatus & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28499/1774_C4_13_cr5950fa3646972_selected.jpg
Normal Tissue
Figure 2 Testis
Figure 2 Testis
(Pachytene spermatocytes Staining: Low Intensity: Moderate Quantity: <25% Peritubular cells Staining: High Intensity: Strong Quantity: 75%-25% Spermatogonia cells Staining: Low Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3842/10254_A_4_6.jpg
Figure 3 Placenta
Figure 3 Placenta
(Decidual cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Trophoblastic cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3842/10254_A_2_7.jpg
Figure 4 Cerebral cortex
Figure 4 Cerebral cortex
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3842/10254_B_9_5.jpg
Figure 5 Liver
Figure 5 Liver
(Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3842/10254_A_9_4.jpg
Figure 6 Kidney
Figure 6 Kidney
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3842/10254_A_8_5.jpg
RNA Expression
Figure 7 RNA cell line category: Group enriched (ASC diff, ASC TERT1)
Figure 7 RNA cell line category: Group enriched (ASC diff, ASC TERT1)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000113721-PDGFRB

Specifications

  • Immunogen
  • Soluble PDGF-R β
  • Host Species
  • Mouse
  • Type
  • Mouse Fab
  • Specificity
  • Human PDGFRB
  • Species Reactivity
  • Human
  • Clone
  • muM4TS.11
  • Applications
  • ELISA, Neut

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • Platelet Derived Growth Factor Receptor Beta; Platelet-Derived Growth Factor Receptor, Beta Polypeptide; Beta-Type Platelet-Derived Growth Factor Receptor; Platelet-Derived Growth Factor Receptor 1; CD140 Antigen-Like Family Member B; PDGF-R-Beta; EC 2.7.10.1; PDGFR-Beta; PDGFR-1; PDGFR1; PDGFR; Platelet-Derived Growth Factor Receptor Beta

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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Human Antibody

CAT Product Name Application Type
TAB-0988CL-S(P) Human Anti-PDGFRB Recombinant Antibody; scFv Fragment (TAB-0988CL-S(P)) ELISA Human scFv
TAB-0989CL-S(P) Human Anti-PDGFRB Recombinant Antibody; scFv Fragment (TAB-0989CL-S(P)) ELISA Human scFv
TAB-0990CL-S(P) Human Anti-PDGFRB Recombinant Antibody; scFv Fragment (TAB-0990CL-S(P)) ELISA Human scFv
TAB-0991CL-S(P) Human Anti-PDGFRB Recombinant Antibody (TAB-0991CL-S(P)); scFv Fragment ELISA Human scFv
TAB-0988CL-F(E) Human Anti-PDGFRB Recombinant Antibody; Fab Fragment (TAB-0988CL-F(E)) ELISA Human Fab

Neutralizing Antibody

CAT Product Name Application Type
NEUT-1850CQ Recombinant Rat Anti-Pdgfrb Antibody (APB5) FC, FuncS, Neut IgG2a, κ

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-2638 Hi-Affi™ Recombinant Rabbit Anti-PDGFRB Monoclonal Antibody (DS2638AB) WB IgG

Recombinant Antibody

CAT Product Name Application Type
MRO-1193-CN Recombinant Rabbit Anti-PDGFRB Monoclonal Antibody (CBACN-438) WB, IHC, IP Rabbit IgG
HPAB-S0105-YC Mouse Anti-PDGFRB Recombinant Antibody (clone muM4TS.11) ELISA, Neut Mouse IgG
HPAB-S0106-YC Human Anti-PDGFRB Recombinant Antibody (clone HuM4TS.11) ELISA, Neut Humanized IgG
HPAB-S0107-YC Mouse Anti-PDGFRB Recombinant Antibody (clone muM4TS.22) ELISA, Neut Mouse IgG
HPAB-S0108-YC Human Anti-PDGFRB Recombinant Antibody (clone HuM4TS.22) ELISA, Neut Humanized IgG

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-448CQ Afuco™ Anti-PDGFRB Recombinant Antibody (AFC-TAB-448CQ), ADCC Enhanced ELISA, IHC, FC, IP, IF, FuncS Human IgG1, κ

scFv Fragment Antibody

CAT Product Name Application Type
HPAB-N0227-YC-S(P) Human Anti-PDGFRB Recombinant Antibody (clone PFH2); scFv Fragment Block Human scFv
HPAB-1110-CN-S(P) Mouse Anti-PDGFRB Recombinant Antibody; scFv Fragment (HPAB-1110-CN-S(P)) ELISA Mouse scFv
HPAB-1111-CN-S(P) Human Anti-PDGFRB Recombinant Antibody; scFv Fragment (HPAB-1111-CN-S(P)) ELISA Human scFv
HPAB-S0107-YC-S(P) Mouse Anti-PDGFRB Recombinant Antibody (clone muM4TS.22); scFv Fragment ELISA, Neut Mouse scFv
HPAB-S0108-YC-S(P) Human Anti-PDGFRB Recombinant Antibody (clone HuM4TS.22); scFv Fragment ELISA, Neut Humanized scFv

Fab Fragment Antibody

CAT Product Name Application Type
HPAB-1110-CN-F(E) Mouse Anti-PDGFRB Recombinant Antibody; Fab Fragment (HPAB-1110-CN-F(E)) ELISA Mouse Fab
HPAB-1111-CN-F(E) Human Anti-PDGFRB Recombinant Antibody; Fab Fragment (HPAB-1111-CN-F(E)) ELISA Human Fab
HPAB-1112-CN-F(E) Human Anti-PDGFRB Recombinant Antibody; Fab Fragment (HPAB-1112-CN-F(E)) ELISA Human Fab
HPAB-S0106-YC-F(E) Human Anti-PDGFRB Recombinant Antibody (clone HuM4TS.11); Fab Fragment ELISA, Neut Humanized Fab
HPAB-S0108-YC-F(E) Human Anti-PDGFRB Recombinant Antibody (clone HuM4TS.22); Fab Fragment ELISA, Neut Humanized Fab

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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