Provided is an antibody huM4TS.11 that specific for the platelet-derived growth factor receptor β. huM4TS.11 does not bind to deletion proteins containing only the first through third domains of PDGF-R β, but does bind to protein D1-4 containing the fourth domain, showing that the binding epitope is in the fourth domain. huM4TS.11 effectively inhibited the stimulation of proliferation by PDGF BB, showing the ability of these antibodies to neutralize the biological activity of PDGF BB.
Figure 1 Human Anti-PDGFRB Recombinant Antibody (HPAB-S0106-YC) in WB
Western blot analysis of HPAB-S0106-YC was performed with recombinant human PDGFRB protein.
HPAB-S0106-YC incubation concentration: 2 ng/μL.
The secondary antibody: HRP-IgG (H+L)
Lane 1: Reducing Antigen (0.1 μg)
Lane 2: Reducing Antigen (0.2 μg)
Lane 3: Reducing Antigen (0.4 μg)
Figure 2 Human Anti-PDGFRB Recombinant Antibody (HPAB-S0106-YC) in ELISA
ELISA analysis of HPAB-S0106-YC was performed by coating with recombinant human PDGFRB protein.
The secondary antibody: HRP-IgG (H+L)
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1734z | Mouse Anti-PDGFRB Recombinant Antibody (clone 1H11) | ELISA, IF, WB | Mouse IgG1 |
MRO-2112-CN | Rabbit Anti-PDGFRB Polyclonal Antibody (MRO-2112-CN) | WB, IF, IHC, FC | Rabbit IgG |
HPAB-N0227-YC | Human Anti-PDGFRB Recombinant Antibody (clone PFH2) | Block | Human IgG |
HPAB-1110-CN | Mouse Anti-PDGFRB Recombinant Antibody (HPAB-1110-CN) | ELISA | Mouse IgG1 |
HPAB-1111-CN | Human Anti-PDGFRB Recombinant Antibody (HPAB-1111-CN) | ELISA | Human IgG4 |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-706CL | Anti-Human PDGFRB Therapeutical Antibody (IMC-2C5) | Inhib, FuncS | Antibody |
TAB-0988CL-S(P) | Human Anti-PDGFRB Recombinant Antibody; scFv Fragment (TAB-0988CL-S(P)) | ELISA | Human scFv |
TAB-0989CL-S(P) | Human Anti-PDGFRB Recombinant Antibody; scFv Fragment (TAB-0989CL-S(P)) | ELISA | Human scFv |
TAB-0990CL-S(P) | Human Anti-PDGFRB Recombinant Antibody; scFv Fragment (TAB-0990CL-S(P)) | ELISA | Human scFv |
TAB-0991CL-S(P) | Human Anti-PDGFRB Recombinant Antibody (TAB-0991CL-S(P)); scFv Fragment | ELISA | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-1850CQ | Recombinant Rat Anti-Pdgfrb Antibody (APB5) | FC, FuncS, Neut | IgG2a, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-2638 | Hi-Affi™ Recombinant Rabbit Anti-PDGFRB Monoclonal Antibody (DS2638AB) | WB | IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-141CQ | Human Anti-Pdgfrb Antibody Fab Fragment (1B3) | FC, WB, Neut | Human Fab |
HPAB-0281CQ-F(E) | Human Anti-PDGFRB Recombinant Antibody (clone 1B3); Fab Fragment | ELISA, FC, WB, Neut | Human Fab |
HPAB-N0227-YC-F(E) | Human Anti-PDGFRB Recombinant Antibody (clone PFH2); Fab Fragment | Block | Human Fab |
HPAB-1110-CN-F(E) | Mouse Anti-PDGFRB Recombinant Antibody; Fab Fragment (HPAB-1110-CN-F(E)) | ELISA | Mouse Fab |
HPAB-1111-CN-F(E) | Human Anti-PDGFRB Recombinant Antibody; Fab Fragment (HPAB-1111-CN-F(E)) | ELISA | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0281CQ-S(P) | Human Anti-PDGFRB Recombinant Antibody (clone 1B3); scFv Fragment | ELISA, FC, WB, Neut | Human scFv |
HPAB-S0105-YC-S(P) | Mouse Anti-PDGFRB Recombinant Antibody (clone muM4TS.11); scFv Fragment | ELISA, Neut | Mouse scFv |
HPAB-S0106-YC-S(P) | Human Anti-PDGFRB Recombinant Antibody (clone HuM4TS.11); scFv Fragment | ELISA, Neut | Humanized scFv |
HPAB-S0107-YC-S(P) | Mouse Anti-PDGFRB Recombinant Antibody (clone muM4TS.22); scFv Fragment | ELISA, Neut | Mouse scFv |
HPAB-S0108-YC-S(P) | Human Anti-PDGFRB Recombinant Antibody (clone HuM4TS.22); scFv Fragment | ELISA, Neut | Humanized scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-448CQ | Afuco™ Anti-PDGFRB Recombinant Antibody (AFC-TAB-448CQ), ADCC Enhanced | ELISA, IHC, FC, IP, IF, FuncS | Human IgG1, κ |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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