Mouse Anti-phosphorylated Tau Recombinant Antibody (clone PHF1) (CAT#: VS-0623-WK88)
The antibody clone PHF1 was produced by immunizing mouse with tau. It is specific for phosphorylated (p-)tau (serine 396 and 404). It can be used for detection of human tau in ELISA, WB, IHC and IF staining.
Specific Inquiry
IHC
Figure 1 Cell lysates and media transfected with iBs and scFvs were applied to paraffin-embedded sections of 10-month-old rTg4510 tau transgenic mice.
Cortical staining of neurofibrillary tangles was visualized with a biotinylated anti-c-myc secondary antibody. EGFP palys as a negative control.
ELISA
Figure 2 Cell lysates and media containing scFvs and iBs were subjected to direct ELISA.
Plates were coated with recombinant full-length tau, p-tau, or amyloid β as a control. Anti-c-myc HRP secondary antibody served as a detection.
FucnS
Figure 3 p-Tau-Specific iBs and scFvs Delay the Onset of Hindlimb Paralysis of Homozygous JNPL3 Mice.
JNPL3 mice for the survival cohort were intraspinally injected at P0 with pAAV2/8 (2 × 10e10 genomes) expressing PHF1, CP13, and Tau5 scFvs. Control mice were injected with rAAV-EGFP. All injected mice reached a terminal state (paralysis) within 12 months post-injection (n = 10-12). Median age of terminal state and relative increase of lifespan.
Specifications
- Immunogen
- Tau
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human tau
- Species Reactivity
- Human
- Clone
- PHF1
- Applications
- ELISA, WB, IHC, IF, FuncS
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No Preservative
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Immunohistochemical staining was done with cell lysates and media containing scFvs and iBs diluted 1/10 with PBS and applied to paraffin-fixed brain tissue slides from 10-month-old mice.
Target
- Alternative Names
- TAU; MSTD; PPND; DDPAC; MAPTL; MTBT1; MTBT2; tau-40; FTDP-17; PPP1R103; Tau-PHF6
- Gene ID
- 4137
- UniProt ID
- P10636
- Long Name
- Microtubule associated protein tau
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "Tau"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-951 | Recombinant Anti-Tau Antibody | ELISA, WB, IP, FuncS | IgG |
| MOB-091LC | Recombinant Humanized Anti-TAU Recombinant Antibody (huHJ8) | ELISA, FuncS | Humanized IgG |
| MOB-0054SW | Human Anti-Tau Recombinant Antibody (MOB-0054SW) | ELISA, FuncS | Humanized IgG4 |
| VS-0623-WK89 | Mouse Anti-phosphorylated Tau Recombinant Antibody (clone CP13) | ELISA, WB, IHC, IF, FuncS | Mouse IgG1 |
| VS-0623-WK90 | Mouse Anti-pan Tau Recombinant Antibody (clone tau5) | ELISA, WB, IHC, IF, FuncS | Mouse IgG1 |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-951-S(P) | Recombinant Anti-Tau Antibody scFv Fragment | FC, Neut, Funcs | scFv |
| MHH-951-S(P) | Recombinant Human Anti-Tau Antibody scFv Fragment | ELISA, WB, FuncS | scFv |
| HPAB-0773LY-S(P) | Human Anti-Tau Recombinant Antibody; scFv Fragment (HPAB-0773LY-S(P)) | ELISA | Human scfv |
| HPAB-S0178-YC-S(P) | Mouse Anti-Tau Recombinant Antibody (clone Tau5); scFv Fragment | ELISA | Mouse scFv |
| FAMAB-0352WJ-S(P) | Mouse Anti-Tau Recombinant Antibody (clone MHT2); scFv Fragment | ELISA, WB, IHC | Mouse scFv |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0428CL | Human Anti-Tau Recombinant Antibody (TAB-0428CL) | ELISA, WB | Human IgG |
| TAB-0429CL | Human Anti-Tau Recombinant Antibody (TAB-0429CL) | ELISA, WB | Human IgG |
| TAB-0427CL-S(P) | Human Anti-Tau Recombinant Antibody; scFv Fragment (TAB-0427CL-S(P)) | ELISA, WB, IHC, FuncS | Human scFv |
| TAB-0428CL-S(P) | Human Anti-Tau Recombinant Antibody; scFv Fragment (TAB-0428CL-S(P)) | ELISA, WB | Human scFv |
| TAB-0429CL-S(P) | Human Anti-Tau Recombinant Antibody; scFv Fragment (TAB-0429CL-S(P)) | ELISA, WB | Human scFv |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-527CT | Human Anti-Tau Recombinant Antibody (TAB-527CT) | IF, FuncS | Humanized antibody |
| TAB-527CT-S(P) | Human Anti-Tau Recombinant Antibody; scFv Fragment (TAB-527CT-S(P)) | WB, ELISA, IHC | Human scFv |
| TAB-533CT-S(P) | Humanized Anti-Tau Recombinant Antibody; scFv Fragment (TAB-533CT-S(P)) | WB, ELISA, IP, IHC, Neut | Humanized scFv |
| TAB-527CT-F(E) | Human Anti-Tau Recombinant Antibody; Fab Fragment (TAB-527CT-F(E)) | WB, ELISA, IHC | Humanized Fab |
| TAB-533CT-F(E) | Humanized Anti-Tau Recombinant Antibody; Fab Fragment (TAB-533CT-F(E)) | WB, ELISA, IP, IHC, Neut | Humanized Fab |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-528CT-S(P) | Anti-Human Tau Recombinant Antibody scFv Fragment (ADx202) | WB, ELISA, IHC | |
| TAB-529CT-S(P) | Mouse Anti-Tau Recombinant Antibody; scFv Fragment (TAB-529CT-S(P)) | WB, ELISA, IF, IHC | Mouse scFv |
| TAB-530CT-S(P) | Anti-Human Tau Recombinant Antibody scFv Fragment (pT231/pS235_1) | WB, ELISA, IP, IHC | |
| TAB-531CT-S(P) | Anti-Human Tau Recombinant Antibody scFv Fragment (pT212/pS214_2) | WB, ELISA, IP, IHC | |
| TAB-532CT-S(P) | Anti-Human Tau Recombinant Antibody scFv Fragment (pS396/pS404_1) | WB, ELISA, IP, IHC |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0773LY-F(E) | Human Anti-Tau Recombinant Antibody; Fab Fragment (HPAB-0773LY-F(E)) | ELISA | Human Fab |
| HPAB-2561LY-F(E) | Human Anti-Tau Recombinant Antibody; Fab Fragment (HPAB-2561LY-F(E)) | WB, IHC, ELISA | Humanized Fab |
| HPAB-2562LY-F(E) | Human Anti-Tau Recombinant Antibody; Fab Fragment (HPAB-2562LY-F(E)) | WB, IHC, ELISA | Humanized Fab |
| HPAB-2563LY-F(E) | Human Anti-Tau Recombinant Antibody; Fab Fragment (HPAB-2563LY-F(E)) | WB, IHC, ELISA | Humanized Fab |
| MOB-0054SW-F(E) | Human Anti-Tau Recombinant Antibody; Fab Fragment (MOB-0054SW-F(E)) | ELISA, FuncS | Humanized Fab |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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