Mouse Anti-PROM1 Monoclonal Antibody (VS7-0425-WR694)
CAT#: VS7-0425-WR694
This product is a mouse IgG antibody that binds to human PROM1. The antibody can be used for IHC-P, IF, FC, and ELISA assays.
Gene Expression
Normal Tissue
Figure 1 Colon
Goblet cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4922/15212_A_8_3.jpg
Normal Tissue
Figure 2 Liver
Cholangiocytes
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4922/15212_A_7_4.jpg
Normal Tissue
Figure 3 Pancreas
Exocrine glandular cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4922/15212_A_2_3.jpg
Normal Tissue
Figure 4 Kidney
Bowman's capsule
Staining:High
Intensity: Strong
Quantity:>75%
Distal tubules
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Proximal tubules (cell body)
Staining:Medium
Intensity: Strong
Quantity: <25%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4922/15212_A_8_5.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (AF22, CACO-2, CAPAN-2, EFO-21, NTERA-2, RPTEC TERT1)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000007062-PROM1
❮
❯
Specifications
- Immunogen
- Synthetic human CD133 peptide
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human PROM1
- Species Reactivity
- Human
- Molecule Class
- Pentaspan Transmembrane Glycoprotein
- Applications
- IHC-P, IF, FC, ELISA
- Conjugate
- Unconjugated
- Related Disease
- Retinitis pigmentosa 41 (RP41); Cone-rod dystrophy 12 (CORD12); Stargardt disease 4 (STGD4); Macular dystrophy, retinal, 2 (MCDR2)
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis, Ascitic fluid
- Format
- Liquid
- Concentration
- 1 mg/ml
- Preservative
- 0.03% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Aliquot and store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Immunohistochemistry: 1:200 - 1:1000
Flow Cytometry: 1:200 - 1:400
Enzyme-linked Immunosorbent Assay: 1:10000
Target
- Alternative Names
- PROM1; MSTP061; HProminin; Prominin 1; Prominin-Like Protein 1; Macular Dystrophy, Retinal 2; STGD4; AC133; MCDR2; Prominin (Mouse)-Like 1; PROML1; CD133; Prominin-1; Hematopoietic Stem Cell Antigen; RP41; Stargardt Disease 4 (Autosomal Dominant); Antigen
- Gene ID
- 8842
- UniProt ID
- O43490
- Long Name
- Prominin 1
- Cellular Localization
- Cell membrane; Cell projection; Cilium; Endoplasmic reticulum; Membrane
- Post Translation Modifications
- Acetylation; Glycoprotein; Phosphoprotein
- Protein Refseq
- NP_001139319.1
- Function
- May play a role in cell differentiation, proliferation and apoptosis (PubMed:24556617).; Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner (PubMed:20818439)
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "PROM1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1990z | Mouse Anti-PROM1 Recombinant Antibody (clone 41D7) | WB, FC, IHC | Mouse IgG1 |
| HPAB-0088-FY | Human Anti-PROM1 Recombinant Antibody (HPAB-0088-FY) | FC | Human IgG1 |
| MRO-0275-CN | Recombinant Mouse Anti-PROM1 Monoclonal Antibody (D2-B1) | IHC, IF | Mouse IgG1 |
| HPAB-1396-FY | Human Anti-PROM1 Recombinant Antibody (clone H133) | FC | Humanized IgG |
| VS7-0425-WR693 | Mouse Anti-PROM1 Recombinant Antibody (clone 2F8C5) | FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B028(A) | Recombinant Anti-human PROM1 Intrabody [(D-Arg)9] | ELISA, Neut, FuncS | scFv-(D-Arg)9 |
| IAB-B028(G) | Recombinant Anti-human PROM1 Intrabody [+36 GFP] | PCA, WB, FuncS | scFv-(+36GFP) |
| IAB-B028(T) | Recombinant Anti-human PROM1 Intrabody [Tat] | FACS, ELISA, IF, FuncS | scFv-Tat |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G057S | Anti-PROM1 immunotoxin (scFv)-Sap | Cytotoxicity assay, Function study |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0375CL-S(P) | Anti-Mouse PROM1 Recombinant Antibody scFv Fragment (293AC1C3H9) | FC | Chimeric (mouse/human) |
| TAB-0376CL-S(P) | Anti-Mouse PROM1 Recombinant Antibody scFv Fragment (SDIE 293) | FC | Chimeric (mouse/human) |
| TAB-0377CL-S(P) | Anti-Mouse PROM1 Recombinant Antibody scFv Fragment (W6B3H10) | FC | Chimeric (mouse/human) |
| TAB-0378CL-S(P) | Anti-Mouse PROM1 Recombinant Antibody scFv Fragment (SDIE W6B3) | FC | Chimeric (mouse/human) |
| TAB-0379CL-S(P) | Anti-Mouse PROM1 Recombinant Antibody scFv Fragment | FC | Chimeric (mouse/human) |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0183-YC-S(P) | Human Anti-PROM1 Recombinant Antibody (clone h133H/h133La); scFv Fragment | ELISA, FC | Humanized scFv |
| HPAB-0088-FY-S(P) | Human Anti-PROM1 Recombinant Antibody; scFv Fragment (HPAB-0088-FY-S(P)) | FC | Human scFv |
| HPAB-1396-FY-F(E) | Human Anti-PROM1 Recombinant Antibody (clone H133); scFv Fragment | FC | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0183-YC-F(E) | Human Anti-PROM1 Recombinant Antibody (clone h133H/h133La); Fab Fragment | ELISA, FC | Humanized Fab |
| HPAB-0088-FY-F(E) | Human Anti-PROM1 Recombinant Antibody; Fab Fragment (HPAB-0088-FY-F(E)) | FC | Human Fab |
| HPAB-1396-FY-S(P) | Human Anti-PROM1 Recombinant Antibody (clone H133); Fab Fragment | FC | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-019CN | Mouse Anti-PROM1 Recombinant Antibody (NS-019CN) | ELISA, IF, IHC, FC | Mouse IgG |
| NS-019CN-F(E) | Mouse Anti-PROM1 Recombinant Antibody; Fab Fragment (NS-019CN-F(E)) | ELISA, IF, IHC, FC | Mouse Fab |
| NS-019CN-S(P) | Mouse Anti-PROM1 Recombinant Antibody; scFv Fragment (NS-019CN-S(P)) | ELISA, IF, IHC, FC | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN1161 | PE-A*02:01/Human PROM1 (YLQWIEFSI) MHC Tetramer | FCM, IHC | |
| MHC-CN1162 | APC-A*02:01/Human PROM1 (YLQWIEFSI) MHC Tetramer | FCM, IHC | |
| MHC-CN1163 | FITC-A*02:01/Human PROM1 (YLQWIEFSI) MHC Tetramer | FCM, IHC | |
| MHC-CN1164 | A*02:01/Human PROM1 (YLQWIEFSI) MHC Tetramer | FCM, IHC | |
| MHC-YF689 | A*02:01/Human Prominin1 (YLQWIEFSI) MHC Pentamer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0060-FY | Rabbit Anti-PROM1 Recombinant Antibody (clone AFY0031) | IF, IHC-P, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0924-YC86 | Mouse Anti-PROM1 Recombinant Antibody (VS-0924-YC86) - Cancer Stem Cell Marker | IHC, WB | Mouse IgG1 |
| VS-0924-YC87 | Rabbit Anti-PROM1 Antibody (VS-0924-YC87) - Cancer Stem Cell Marker | IHC, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY181 | CytoStream™ Mouse Anti-PROM1 Recombinant Antibody (clone 293C3) | FC | Mouse IgG2b, kappa |
| VS-0225-XY182 | CytoStream™ Mouse Anti-PROM1 Recombinant Antibody (VS-0225-XY182) | FC | Mouse IgG1, kappa |
| VS13-YC944 | CytoStream™ Mouse Anti-PROM1 Recombinant Antibody (VS13-YC944) | WB, IHC-P, FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC266 | Recombinant Anti-PROM1 Vesicular Antibody, EV Displayed (VS-0425-YC266) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY5735 | Anti-PROM1 Immunohistochemistry Kit | IHC |
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