Human Anti-ROR1 Recombinant Antibody Hexamer (VS-0924-YC148), CDC Enhanced (CAT#: VS-0924-YC148)
The product is a human anti-ROR1 antibody hexamer with enhanced CDC activity. This hexameric IgG1, which targets human ROR1, includes hexamerization-enhancing mutations that promote hexamer formation, resulting in optimal C1q binding and boosted complement-dependent cytotoxicity (CDC).
Specific Inquiry
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, CACO-2, HHSteC, HSkMC, NTERA-2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000185483-ROR1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000185483-ROR1
Specifications
- Host Species
- Human
- Derivation
- Chimeric (rabbit/human)
- Type
- Antibody hexamer
- Specificity
- Human ROR1
- Species Reactivity
- Human
- Molecule Class
- ~ 900 kDa
- Applications
- ELISA, SPR, FC, ADCC, CDC
- Conjugate
- None
- Related Disease
- Breast cancer
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A purified
- Purity
- >95% determined as SDS-PAGE and SEC-HPLC
- Aggregation
- <5%
- Buffer
- PBS, pH 7.4
- Preservative
- No preservatives
- Storage
- Store at 4°C short term (1-2 weeks). Store at -20°C long term (12 months). Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- NTRKR1; dJ537F10.1
- Gene ID
- 4919
- UniProt ID
- Q01973
- Long Name
- Receptor Tyrosine Kinase Like Orphan Receptor 1
Downloads
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-336CT-S(P) | Mouse Anti-ROR1 Recombinant Antibody; scFv Fragment (TAB-336CT-S(P)) | WB, ELISA, FC | Mouse scFv |
| TAB-337CT-S(P) | Mouse Anti-ROR1 Recombinant Antibody; scFv Fragment (TAB-337CT-S(P)) | WB, ELISA, FC | Mouse scFv |
| TAB-338CT-S(P) | Mouse Anti-ROR1 Recombinant Antibody; scFv Fragment (TAB-338CT-S(P)) | WB, ELISA, FC | Mouse scFv |
| TAB-336CT-F(E) | Mouse Anti-ROR1 Recombinant Antibody; Fab Fragment (TAB-336CT-F(E)) | WB, ELISA, FC | Mouse Fab |
| TAB-337CT-F(E) | Mouse Anti-ROR1 Recombinant Antibody; Fab Fragment (TAB-337CT-F(E)) | WB, ELISA, FC | Mouse Fab |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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