Mouse Anti-ROR1 Recombinant Antibody Hexamer (VS-0924-YC149), CDC Enhanced (CAT#: VS-0924-YC149)
The product is a hexameric mouse anti-ROR1 antibody with enhanced complement-dependent cytotoxicity (CDC) activity. This IgG1 antibody, which targets human ROR1, features hexamerization-enhancing mutations. These mutations promote hexamer formation, facilitating optimal C1q binding and thereby boosting CDC efficacy.
Specific Inquiry
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, CACO-2, HHSteC, HSkMC, NTERA-2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000185483-ROR1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000185483-ROR1
Specifications
- Host Species
- Mouse
- Type
- Antibody hexamer
- Specificity
- Human ROR1
- Species Reactivity
- Human
- Molecule Class
- ~ 900 kDa
- Applications
- ELISA, FC, CDC
- Conjugate
- None
- Related Disease
- Lymphomas, leukemia, and solid tumors such as breast, colon, lung, and kidney tumors
Product Property
- Clonality
- Monoclonal
- Purification
- Protein G purified
- Purity
- >95% determined as SDS-PAGE and SEC-HPLC
- Aggregation
- <5%
- Buffer
- PBS, pH 7.4
- Preservative
- No preservatives
- Storage
- Store at 4°C short term (1-2 weeks). Store at -20°C long term (12 months). Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- ROR1; receptor tyrosine kinase-like orphan receptor 1; NTRKR1; dJ537F10.1; tyrosine-protein kinase transmembrane receptor ROR1; neurotrophic tyrosine kinase, receptor-related 1
- Gene ID
- 4919
- UniProt ID
- Q01973
- Long Name
- Receptor Tyrosine Kinase Like Orphan Receptor 1
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IgG Antibody Products
Mouse Antibody Products
Human Antibody Products
Fab Antibody Products
ScFv Antibody Products
Hexamer Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1937z | Mouse Anti-ROR1 Recombinant Antibody (clone 31C12) | WB, ELISA, ICC, IF | Mouse IgG1 |
| HPAB-0217-CN | Human Anti-ROR1 Recombinant Antibody (HPAB-0217-CN) | ELISA, FC | Chimeric (rabbit/human) IgG1 |
| HPAB-0174-LSX | Human Anti-ROR1 Recombinant Antibody (HPAB-0174-LSX) | ELISA, SPR, FC, ADCC, CDC, FuncS | Humanized IgG1 |
| HPAB-0175-LSX | Human Anti-ROR1 Recombinant Antibody (HPAB-0175-LSX) | ELISA, SPR, FC, ADCC, CDC, FuncS | Human IgG1 |
| HPAB-0176-LSX | Human Anti-ROR1 Recombinant Antibody (HPAB-0176-LSX) | SPR, FC, ELISA, Cyt, Apop | Humanized IgG1 |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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