Recombinant Anti-ROR1 Vesicular Antibody, EV Displayed (VS-0425-YC619)
CAT#: VS-0425-YC619
The Recombinant Anti-ROR1 Vesicular Antibody, EV Displayed (VS-0425-YC619) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to ROR1-expressed cells or tissues. ROR1 is a receptor involved in central nervous system neurite growth, interacting with non-canonical Wnt signaling. Altered expression associates with chronic lymphocytic leukemia.
Gene Expression
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, CACO-2, HHSteC, HSkMC, NTERA-2)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000185483-ROR1
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- ROR1
- Host Animal
- Human
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- z domain
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Binding Affinity
- Kd = 0.85 µg/mL
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Biological Process
- Wnt signaling pathway
- Molecular Function
- Kinase, Receptor, Transferase
- Introduction
- This gene encodes a receptor tyrosine kinase-like receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2012]
- Alternative Names
- NTRKR1
- Gene ID
- 4919
- UniProt ID
- Q01973
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Datasheet
MSDS
COA
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-336CT | Mouse Anti-ROR1 Recombinant Antibody (TAB-336CT) | WB, ELISA, FC | Mouse IgG1 |
| TAB-337CT | Mouse Anti-ROR1 Recombinant Antibody (TAB-337CT) | WB, FC, Cyt | Mouse IgG1 |
| TAB-338CT | Mouse Anti-ROR1 Recombinant Antibody (TAB-338CT) | WB, FC, Cyt | Mouse IgG1 |
| TAB-336CT-F(E) | Mouse Anti-ROR1 Recombinant Antibody; Fab Fragment (TAB-336CT-F(E)) | WB, ELISA, FC | Mouse Fab |
| TAB-337CT-F(E) | Mouse Anti-ROR1 Recombinant Antibody; Fab Fragment (TAB-337CT-F(E)) | WB, ELISA, FC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-339CT | Human Anti-ROR1 Recombinant Antibody (TAB-339CT) | WB, ELISA, FC | Human antibody |
| TAB-340CT | Human Anti-ROR1 Recombinant Antibody (TAB-340CT) | WB, ELISA, FC | Human antibody |
| TAB-341CT | Human Anti-ROR1 Recombinant Antibody (TAB-341CT) | WB, ELISA, FC, IF, BL | Human IgG |
| TAB-342CT | Human Anti-ROR1 Recombinant Antibody (TAB-342CT) | WB, ELISA, FC, IF, BL | Human IgG |
| TAB-343CT | Human Anti-ROR1 Recombinant Antibody (TAB-343CT) | WB, ELISA, FC, IF, BL | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0174-LSX-F(E) | Human Anti-ROR1 Recombinant Antibody; Fab Fragment (HPAB-0174-LSX-F(E)) | ELISA, FC | Humanized Fab |
| HPAB-0175-LSX-F(E) | Human Anti-ROR1 Recombinant Antibody; Fab Fragment (HPAB-0175-LSX-F(E)) | ELISA, FC | Humanized Fab |
| HPAB-0176-LSX-F(E) | Human Anti-ROR1 Recombinant Antibody; Fab Fragment (HPAB-0176-LSX-F(E)) | ELISA, FC | Humanized Fab |
| HPAB-0177-LSX-F(E) | Human Anti-ROR1 Recombinant Antibody (clone CBL01Q); Fab Fragment | ELISA, FC | Human Fab |
| HPAB-0179-LSX-F(E) | Human Anti-ROR1 Recombinant Antibody; Fab Fragment (HPAB-0179-LSX-F(E)) | ELISA, FC, IF, IHC | Chimeric Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0566LY-S(P) | Human Anti-ROR1 Recombinant Antibody scFv Fragment (HPAB-0566LY-S(P)) | ELISA, RIA, FC, Inhib, WB | Humanized scfv |
| HPAB-0567LY-S(P) | Human Anti-ROR1 Recombinant Antibody scFv Fragment (HPAB-0567LY-S(P)) | ELISA, RIA, FC, Inhib, WB | Humanized scfv |
| HPAB-0568LY-S(P) | Human Anti-ROR1 Recombinant Antibody scFv Fragment (HPAB-0568LY-S(P)) | ELISA, RIA, FC, Inhib, WB | Humanized scfv |
| HPAB-0569LY-S(P) | Human Anti-ROR1 Recombinant Antibody scFv Fragment (HPAB-0569LY-S(P)) | ELISA, RIA, FC, Inhib, WB | Humanized scfv |
| HPAB-0570LY-S(P) | Human Anti-ROR1 Recombinant Antibody scFv Fragment (HPAB-0570LY-S(P)) | ELISA, RIA, FC, Inhib, WB | Humanized scfv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0566LY | Human Anti-ROR1 Recombinant Antibody (HPAB-0566LY) | ELISA, RIA, FC, Inhib, WB | Humanized IgG1 |
| HPAB-0567LY | Human Anti-ROR1 Recombinant Antibody (HPAB-0567LY) | ELISA, RIA, FC, Inhib, WB | Humanized IgG1 |
| HPAB-0568LY | Human Anti-ROR1 Recombinant Antibody (HPAB-0568LY) | ELISA, RIA, FC, Inhib, WB | Humanized IgG1 |
| HPAB-0569LY | Human Anti-ROR1 Recombinant Antibody (HPAB-0569LY) | ELISA, RIA, FC, Inhib, WB | Humanized IgG1 |
| HPAB-0570LY | Human Anti-ROR1 Recombinant Antibody (HPAB-0570LY) | ELISA, RIA, FC, Inhib, WB | Humanized IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0924-YC148 | Human Anti-ROR1 Recombinant Antibody Hexamer (VS-0924-YC148), CDC Enhanced | ELISA, SPR, FC, ADCC, CDC | Antibody hexamer |
| VS-0924-YC149 | Mouse Anti-ROR1 Recombinant Antibody Hexamer (VS-0924-YC149), CDC Enhanced | ELISA, FC, CDC | Antibody hexamer |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0125-FY36 | Human Anti-ROR1 scFv-Fc Chimera (VS-0125-FY36) | ADCC, CDC | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1937 | Anti-ROR1 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-YC155 | Recombinant Anti-ROR1 (AA 132-153 x AA 904-918) Biparatopic Antibody, Tandem scFv | ELISA, FC | Tandem scFv |
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