Mouse Anti-SEB Recombinant Antibody (clone pComb-49)

CAT#: VS-0323-CJ50

This mouse anti-SEB antibody (clone pComb-49) is a product that recognizes Staphylococcal enterotoxin B (SEB).

Specifications

  • Immunogen
  • Maltose-binding protein (MBP) fused with the N-terminal 15-mer peptide of SEB (N15-MBP protein)
  • Host Species
  • Mouse
  • Type
  • Mouse IgG
  • Specificity
  • Staphylococcal enterotoxin B (SEB)
  • Species Reactivity
  • S. aureus
  • Clone
  • pComb-49
  • Applications
  • Enzyme-linked Immunosorbent Assay, Western Blot, Surface Plasmon Resonance
  • Conjugate
  • Unconjugated
  • Related Disease
  • Food poisoning

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Buffer
  • PBS
  • Storage
  • Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • ELISA: 0.5-1 μg/well
    Western Blot: 1-10 μg/well
    Surface Plasmon Resonance: 12 nM-30 nM

Target

  • Alternative Names
  • Staphylococcal enterotoxin B
  • Sequence Similarities
  • Belongs to the staphylococcal/streptococcal toxin family.
  • Cellular Localization
  • Secreted
  • Function
  • Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. In turn, this ternary complex activates a large number of T-lymphocytes initiating a systemic release of pro-inflammatory cytokines (PubMed:2303780, PubMed:25015819).
    Causes also the intoxication staphylococcal food poisoning syndrome (By similarity).
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

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COA

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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