Human Anti-SHH Recombinant Antibody (clone 1G12) (CAT#: HPAB-AP789-YC)
The described is a fully human monoclonal antibody (clone 1G12) against human sonic hedgehog homolog (Shh). Soluble recombinant human Shh and KLH-conjugated Shh (Shh-KLH) was used as an immunogen for the mAb generation. The antibody is useful in the treatment studies of diseases associated with the activity and overproduction of Shh and as diagnostics.
Specific Inquiry
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (EFO-21, GAMG, OE19, RT4)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000164690-SHH/subcellular
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000164690-SHH/subcellular
Specifications
- Immunogen
- Soluble recombinant human Shh and KLH-conjugated Shh (Shh-KLH)
- Host Species
- Human
- Type
- Human IgG
- Specificity
- Human SHH
- Species Reactivity
- Human
- Clone
- 1G12
- Applications
- ELISA, Inhib
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Sonic Hedgehog; Shh Unprocessed N-Terminal Signaling And C-Terminal Autoprocessing Domains; ShhNC; Sonic Hedgehog (Drosophila) Homolog; Sonic Hedgehog Homolog (Drosophila); Sonic Hedgehog Homolog; Sonic Hedgehog Protein; MCOPCB5
- Gene ID
- 6469
- UniProt ID
- Q15465
Related Resources
JAK-STAT Signaling Pathway
Pancreatic Cancer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone 1G12"
See other products for "SHH"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-902 | Recombinant Anti-human SHH Antibody | ELISA, WB, Neut, FuncS | IgG |
| MHH-902 | Recombinant Human Anti-human SHH Antibody | WB, IHC, FuncS | IgG |
| MRO-1420-CN | Recombinant Rabbit Anti-SHH Monoclonal Antibody (CBACN-518) | WB, IF, IHC, FC | Rabbit IgG |
| HPAB-N0236-YC | Mouse Anti-SHH Recombinant Antibody (HPAB-N0236-YC) | ELISA, FC, WB, FuncS, Inhib, IF | Mouse IgG |
| VS3-FY1333 | Recombinant Rabbit Anti-SHH Antibody (clone R06-9H9) | WB, IHC-Fr, IHC-P, ICC, IF | Rabbit IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-902-S(P) | Recombinant Anti-human SHH Antibody scFv Fragment | IP, IF, Biosensors, FuncS | scFv |
| MHH-902-S(P) | Recombinant Human Anti-human SHH Antibody scFv Fragment | ELISA, WB, IF, FuncS | scFv |
| PSBL-696 | Mouse Anti-SHH Recombinant Antibody (clone 5E1); scFv Fragment | Neut | Mouse scFv |
| HPAB-0710-CN-S(P) | Human Anti-SHH Recombinant Antibody (clone 3H8); scFv Fragment | ELISA, FC | Human scFv |
| HPAB-N0236-YC-S(P) | Mouse Anti-SHH Recombinant Antibody; scFv Fragment (HPAB-N0236-YC-S(P)) | ELISA, FC, WB, FuncS | Mouse scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-902-F(E) | Recombinant Human Anti-human SHH Antibody Fab Fragment | WB, FC, FuncS | Fab |
| HPAB-0710-CN-F(E) | Human Anti-SHH Recombinant Antibody (clone 3H8); Fab Fragment | ELISA, FC | Human Fab |
| HPAB-0711-CN-F(E) | Human Anti-SHH Recombinant Antibody (clone 6D7OP); Fab Fragment | ELISA, FC, Neut | Human Fab |
| HPAB-AP788-YC-F(E) | Human Anti-SHH Recombinant Antibody (clone 1A12); Fab Fragment | ELISA, Inhib | Human Fab |
| HPAB-AP789-YC-F(E) | Human Anti-SHH Recombinant Antibody (clone 1G12); Fab Fragment | ELISA, Inhib | Human Fab |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-566CL | Anti-Human SHH Recombinant Antibody (MEDI-5304) | Inhib | Antibody |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1955CQ | Recombinant Rat Anti-Shh Antibody (6K12) | IHC, Neut, WB | IgG2 |
| NEUT-1956CQ | Recombinant Rat Anti-Shh Antibody (CBL167) | IHC, Neut, WB | IgG2 |
| NEUT-1957CQ | Recombinant Rat Anti-Shh Antibody (CBL886) | Neut, WB | IgG2a |
| NEUT-1958CQ | Recombinant Mouse Anti-SHH Antibody (171018) | IHC-FoFr, WB, IHC-Fr, Neut, ELISA, ICC/IF | IgG2a |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3261 | Hi-Affi™ Recombinant Rabbit Anti-SHH Monoclonal Antibody (DS3261AB) | FC, IHC-P, IP, WB | IgG |
| MOR-4739 | Hi-Affi™ Recombinant Rabbit Anti-SHH Monoclonal Antibody (TH253DS) | WB, IF, ICC, FC | IgG |
Neuroscience Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-082CN | Human Anti-SHH Recombinant Antibody (clone 6D7) | ELISA, FC | Human IgG2 |
| NS-082CN-F(E) | Human Anti-SHH Recombinant Antibody (clone 6D7); Fab Fragment | ELISA, FC | Human Fab |
| NS-082CN-S(P) | Human Anti-SHH Recombinant Antibody (clone 6D7); scFv Fragment | ELISA, FC | Human scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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