AbPlus™ Anti-STAT1 Magnetic Beads (CBACN-527)
CAT#: VS-0424-XY248
The AbPlus Anti-STAT1 Magnetic Beads (CBACN-527) is an innovative affinity resin which is bound with anti-STAT1 specific antibody (CBACN-527). The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of STAT1 protein under native and denaturing conditions.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IHC staining of human lymph node
Immunohistochemical staining of human lymph node shows cytoplasmic positivity in non-germinal center cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/931/2258_A_7_8_selected.jpg
Normal Tissue
Figure 2 Kidney
Cells in glomeruli
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous
Cells in tubules
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/931/2258_A_7_5.jpg
Normal Tissue
Figure 3 Testis
Cells in seminiferous ducts
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/931/2258_A_6_6.jpg
Normal Tissue
Figure 4 Lymph node
Germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/931/2258_A_7_8.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (BJ hTERT+ SV40 Large T+, BJ hTERT+ SV40 Large T+ RasG12V)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000115415-STAT1/subcellular
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magrose bead (> 50 μmol/mL gel)
- Bead Ligand
- Anti-STAT1 specific antibody (CBACN-527)
- Target
- STAT1
- Immunogen
- C-terminus of human STAT1
- Target Species
- Human, Mouse
- Antibody Clone
- CBACN-527
- Bead Capacity
- 20-30 mg/mL binding antibody
- Bead size
- 10-37 μm
- Stability
- pH 2-14
- Format
- 20% Suspension
- Buffer
- PBS, pH 7.4, with 1% BSA
- Preservative
- 0.03% Proclin 300
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.
- Alternative Names
- CANDF7; IMD31A; IMD31B; IMD31C; ISGF-3; STAT91
- Gene ID
- 6772
- UniProt ID
- P42224
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Related Signaling Pathways
MAPK Signaling Pathway
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "STAT1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1538MZ | Recombinant Mouse Anti-Human STAT1 Antibody (clone QTN2) | IP, WB | Mouse antibody |
| MRO-1434-CN | Recombinant Mouse Anti-STAT1 Monoclonal Antibody (G3-B11) | WB, IF, IHC | Mouse IgG2b |
| MRO-1435-CN | Recombinant Rabbit Anti-STAT1 Monoclonal Antibody (CBACN-527) | WB, IP, FC | Rabbit IgG |
| VS3-QX1057 | Mouse Anti-STAT1 Recombinant Antibody (clone 6C2-F7-D12) | WB, IP | Mouse IgG2a |
| VS3-QX1058 | Mouse Anti-STAT1 Recombinant Antibody (clone 10F1-3C3-7F1) | IHC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0563MZ | Chicken Anti-STAT1 (ab1) Polyclonal IgY | WB | Chicken antibody |
| BRD-0564MZ | Chicken Anti-STAT1 (ab2) Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3425 | Hi-Affi™ Recombinant Rabbit Anti-STAT1 Monoclonal Antibody (DS3425AB) | WB | IgG |
| MOR-4710 | Hi-Affi™ Recombinant Rabbit Anti-STAT1 Monoclonal Antibody (TH224DS) | WB, IF, ICC, IHC-P | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN0335 | APC-A*02:01/Human STAT-1 (VLWDRTFSL) MHC Tetramer | FCM | |
| MHC-CN0336 | PE-A*02:01/Human STAT-1 (VLWDRTFSL) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC962 | AbPlus™ Anti-STAT1 Magnetic Beads (VS-0724-YC962) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY492 | Rabbit Anti-NHP STAT1 Recombinant Antibody (VS-1024-XY492) | WB, IHC, IF | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC1116 | CytoStream™ Rabbit Anti-STAT1 Recombinant Antibody (VS13-YC1116) | WB, IP, FC | Rabbit IgG |
| VS13-YC1117 | CytoStream™ Rabbit Anti-STAT1 Recombinant Antibody (VS13-YC1117) | WB, ICC, IF, IHC-P, IP, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY2193 | Anti-STAT1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY6947 | Anti-Mouse STAT1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY6946 | Anti-Human STAT1 Immunohistochemistry Kit | IHC |
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