Anti-TIMP1 (clone HuCAL) Recombinant Antibody Coupled Liposome (VS-1024-FY132) (CAT#: VS-1024-FY132)

• Potential Clinical Applications
• Glioma

• Clone
• HuCAL

• Antibody Type
• IgG

• Antibody Host
• Human

• Antibody Reactivity
• Human

• Antibody Description
• This is a recombinant human monoclonal antibody that has been engineered to specifically recognize and bind to human Tissue Inhibitor of Metalloproteinases 1 (TIMP1). Monoclonal antibodies are laboratory-made molecules that can mimic the immune system's ability to fight off harmful pathogens such as viruses. In this case, the antibody is designed to target TIMP1, a key regulatory protein involved in the inhibition of metalloproteinases, which are enzymes that degrade extracellular matrix proteins.

• Storage
• See in the COA

• Storage Shelf Time
• See in the COA

• Target
• TIMP1

• Introduction
• This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction.

• Alternative Names
• TIMP Metallopeptidase Inhibitor 1; Tissue Inhibitor Of Metalloproteinases 1; Fibroblast Collagenase Inhibitor; Collagenase Inhibitor; TIMP-1; CLGI; TIMP; EPA

• Full Name
• TIMP Metallopeptidase Inhibitor 1

• Gene ID
• 7076

• UniProt ID
• P01033

• Cellular Localization
• Secreted

• HPAB-0174-YC
• Human Anti-TIMP1 Recombinant Antibody (clone HuCAL)

• HPAB-0174-YC-S(P)
• Human Anti-TIMP1 Recombinant Antibody (clone HuCAL); scFv Fragment

• HPAB-0174-YC-F(E)
• Human Anti-TIMP1 Recombinant Antibody (clone HuCAL); Fab Fragment

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