Recombinant Human Anti-GPC3 Soluble TCR (P2-1) (ZIP-Fos/ZIP-Jun) (CAT#: VS-0622-YF140)
Human TCR (P2-1) recognizes GPC3 peptide (TIHDSIQYV) in the context of HLA-A2. Soluble TCR expressed with ZIP-Fos/ZIP-Jun strategy (TRAV-TRAC partial-ZIP-Fos, TRBV-TRBC partial-ZIP-Jun) was validated to be able to bind pMHC in published references. The same expression strategy (ZIP-Fos/ZIP-Jun) is used to express this recombinant Human soluble TCR (P2-1). Please note that the activity is not guaranteed.
Specific Inquiry
Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line Hep G2
(Immunofluorescent staining of human cell line Hep G2 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/6316/1404_H7_2_selected.jpg
(Immunofluorescent staining of human cell line Hep G2 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/6316/1404_H7_2_selected.jpg
Figure 2 RNA cell line category: Group enriched (HAP1, Hep G2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000147257-GPC3
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000147257-GPC3
Specifications
- Host Species
- Human
- Target
- GPC3
- Species Reactivity
- Human
- Epitope
- TIHDSIQYV
- MHC
- HLA-A2
- Clone
- P2-1
- Type
- Soluble TCR (ZIP-Fos/ZIP-Jun)
- Related Disease
- Hepatocellular carcinoma
- TCR Expression Strategy
- ZIP-Fos/ZIP-Jun strategy: the alpha and beta chain (without transmembrane and cytosolic region) can form heterodimer based on ZIP-Fox/ZIP-Jun. The soluble TCR contains variable regions and partial constant regions.
Target
- Alternative Names
- GPC3; glypican 3; SGB; DGSX; MXR7; SDYS; SGBS; OCI-5; SGBS1; GTR2-2; glypican-3; secreted glypican-3; glypican proteoglycan 3
- Gene ID
- 2719
- UniProt ID
- P51654
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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