Mouse Anti-CD5 (clone Zolimomab) scFv-Fc Chimera (CAT#: VS-0425-FY87)
CD5 is a cell surface molecule expressed on T cells and some B cells, involved in immune cell signaling. This scFv-Fc construct targets CD5 and is being researched for its potential applications in modulating immune responses.
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Normal Tissue
RNA Expression
Figure 1 Testis
(Spermatogonia cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/43416/101306_A_5_6.jpg
(Spermatogonia cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/43416/101306_A_5_6.jpg
Figure 2 Lymph node
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/43416/101306_A_7_8.jpg
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/43416/101306_A_7_8.jpg
Figure 3 Tonsil
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/43416/101306_A_5_8.jpg
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/43416/101306_A_5_8.jpg
Figure 4 RNA cell line category: Group enriched (JURKAT, MOLT-4)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000110448-CD5
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000110448-CD5
Figure 4 RNA cell line category: Group enriched (JURKAT, MOLT-4)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000110448-CD5
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000110448-CD5
Specifications
- Immunogen
- Human CD5 protein as an immunogen.
- Host Species
- Mouse
- Type
- Mouse IgG1, scFv-Fc
- Specificity
- Human CD5
- Species Reactivity
- Human
- Clone
- Zolimomab
- Applications
- ELISA
- Related Disease
- Thymus Cancer and Richter's Syndrome
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- The optimal dilution concentration is determined by the experiment.
Target
- Alternative Names
- CD5 Molecule; Lymphocyte Antigen T1/Leu-1; CD5 Antigen (P56-62); LEU1; T-Cell Surface Glycoprotein CD5; CD5 Antigen; T1
- Gene ID
- 921
- UniProt ID
- P06127
- Long Name
- CD5 Molecule
- Cellular Localization
- Cell membrane, Membrane
- Post Translation Modifications
- Phosphorylated on tyrosine residues by LYN; this creates binding sites for PTPN6/SHP-3.
- Protein Refseq
- NP_001333385.1; NP_055022.4N
- Function
- May act as a receptor in regulating T-cell proliferation.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-884 | Mouse Anti-CD5 Recombinant Antibody (clone Zolimomab) | IP, IF, FuncS, FC, Neut, ELISA, ICC | Mouse IgG1 |
| TAB-885 | Mouse Anti-CD5 Recombinant Antibody (clone Telimomab); Fab Fragment | FuncS, IF, Neut, ELISA, FC, IP, ICC | Mouse Fab |
| TAB-308LC | Anti-Human CD5 Recombinant Antibody (5D7) | Cyt, FC, FuncS | |
| TAB-308LC-S(P) | Anti-Human CD5 Recombinant Antibody scFv Fragment (5D7) | FC, SPR | |
| TAB-308LC-F(E) | Anti-Human CD5 Recombinant Antibody Fab Fragment (5D7) | FC, SPR |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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