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    Recombinant Human Anti-ADCYAP1R1 Antibody (clone Zelminemab) (CAT#: VS-0923-FY253)

    Zelminemab (AMG-301) is a monoclonal antibody derived from humans that works by blocking the PAC1 receptor, which is involved in pain signaling. Administered intravenously at a dose of 10 mg/kg, Zelminemab has been shown to decrease the activity of pain-sensing neurons in the TCC.

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    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

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    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line SH-SY5Y
    Figure 1 IF staining of human cell line SH-SY5Y
    (Immunofluorescent staining of human cell line SH-SY5Y shows localization to vesicles.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/30739/1735_E10_1_selected.jpg
    Normal Tissue
    Figure 2 High expression in cerebral cortex
    Figure 2 High expression in cerebral cortex
    (Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/49877/113058_B_7_5.jpg
    Figure 3 Colon
    Figure 3 Colon
    (Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/49877/113058_A_9_3.jpg
    Figure 4 Kidney
    Figure 4 Kidney
    (Cells in glomeruli Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/49877/113058_A_9_5.jpg
    Figure 5 Testis
    Figure 5 Testis
    (Leydig cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/49877/113058_A_4_6.jpg
    RNA Expression
    Figure 6 RNA cell line category: Cell line enhanced (AF22, NTERA-2, SCLC-21H, SH-SY5Y)
    Figure 6 RNA cell line category: Cell line enhanced (AF22, NTERA-2, SCLC-21H, SH-SY5Y)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000078549-ADCYAP1R1

    Specifications

    • Host Species
    • Human
    • Type
    • Human IgG1, kappa
    • Specificity
    • Human ADCYAP1R1
    • Species Reactivity
    • Human
    • Clone
    • Zelminemab
    • Applications
    • Inhibition
    • Conjugate
    • Unconjugated

    Product Property

    • Purification
    • Protein A purified
    • Purity
    • >95%
    • Storage
    • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

    Target

    • Alternative Names
    • ADCYAP Receptor Type I; Adenylate Cyclase Activating Polypeptide 1 (Pituitary) Receptor Type I; Pituitary Adenylate Cyclase-Activating Polypeptide Type 1 Receptor; PACAP Type I Receptor; PACAP Receptor 1; PACAP-R1; Pituitary Adenylate Cyclase Activating Polypeptide 1 Receptor Type I Hiphop; AMG-301

    Recommended Products

    Secondary Antibody

    Isotype Control

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "ADCYAP1R1"

    Select a product category from the dropdown menu below to view related products.
    Please select product type
    IgG Antibody Products Mouse Antibody Products Human Antibody Products Deglycosylated Antibody Products Fab Antibody Products ScFv Antibody Products Antibody Magnetic Beads Extracellular Vesicle (EV) Antibody Products
    CAT Product Name Application Type
    MOB-3850z Mouse Anti-ADCYAP1R1 Recombinant Antibody (clone 15H5) WB, IP, ELISA Mouse IgG1, κ
    MOB-1526CT Mouse Anti-ADCYAP1R1 Recombinant Antibody (clone EML304) IF, WB Mouse IgG1
    HPAB-0039CQ Human Anti-ADCYAP1R1 Recombinant Antibody (HPAB-0039CQ) ELISA, Block Human IgG1, κ
    HPAB-0431-YJ Human Anti-ADCYAP1R1 Recombinant Antibody (HPAB-0431-YJ) Block, FuncS Human IgG2, κ
    HPAB-0432-YJ Human Anti-ADCYAP1R1 Recombinant Antibody (HPAB-0432-YJ) Block, FuncS Human IgG2, κ

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