Recombinant Rabbit Anti-Mouse AGER Detection Antibody (clone R38-7F-9) (CAT#: VS3-WK1915)
This antibody is a rabbit recombinant antibody against mouse AGER. It was developed by immunization of rabbit with recombinant mouse AGER protein and then was produced as a recombinant antibody. The isotype of this product is rabbit IgG. R18-9X-4 and R38-7F-9 were identified as antibody pair for sandwich ELISA. As a detection antibody, the clone R38-7F-9 can be used in ELISA analysis to identify mouse AGER.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line MCF7
(Immunofluorescent staining of human cell line MCF7 shows localization to nucleoli fibrillar center & cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/64436/1232_G12_3_selected.jpg
(Immunofluorescent staining of human cell line MCF7 shows localization to nucleoli fibrillar center & cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/64436/1232_G12_3_selected.jpg
Figure 2 Lung
(Alveolar cells type I
Staining: High
Intensity: Strong
Quantity:>75%
Alveolar cells type II
Staining: Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69474/168057_A_2_4.jpg
(Alveolar cells type I
Staining: High
Intensity: Strong
Quantity:>75%
Alveolar cells type II
Staining: Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/69474/168057_A_2_4.jpg
Figure 3 RNA cell line category: Cell line enhanced (HEK93, JURKAT, RPTEC TERT1, U-266/70, U-266/84)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000204305-AGER
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000204305-AGER
Specifications
- Immunogen
- Recombinant mouse AGER protein
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Mouse AGER
- Species Reactivity
- Mouse
- Clone
- R38-7F-9
- Applications
- ELISA
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Aggregation
- < 5%
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 0.01M PBS, pH 7.2
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- RAGE
- Gene ID
- 11596
- UniProt ID
- Q62151
- Long Name
- Advanced glycosylation end product-specific receptor
- Cellular Localization
- Membrane
- Post Translation Modifications
- Phosphorylated on its cytoplasmic domain by PKCzeta/PRKCZ upon ligand binding.
Targeted by the ubiquitin E3 ligase subunit FBXO10 to mediate its ubiquitination and degradation.
- Protein Refseq
- NP_001258351.1
- Function
- Cell surface pattern recognition receptor that senses endogenous stress signals with a broad ligand repertoire including advanced glycation end products, S100 proteins, high-mobility group box 1 protein/HMGB1, amyloid beta/APP oligomers, nucleic acids, phospholipids and glycosaminoglycans.
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-44 | Recombinant Anti-human AGER Antibody | WB, FC, FuncS | IgG |
| HPAB-0341-FY | Mouse Anti-AGER Recombinant Antibody (HPAB-0341-FY) | WB, IHC, ELISA, FC | Mouse IgG, κ |
| VS3-WK1912 | Recombinant Rabbit Anti-Rat AGER Capture Antibody (clone R45-9J-5) | ELISA | Rabbit IgG |
| VS3-WK1913 | Recombinant Rabbit Anti-Rat AGER Detection Antibody (clone R87-7G-5) | ELISA | Rabbit IgG |
| VS3-WK1914 | Recombinant Rabbit Anti-Mouse AGER Capture Antibody (clone R18-9X-4) | ELISA | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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