Recombinant Rabbit Anti-Mouse AGER Detection Antibody (clone R38-7F-9)
CAT#: VS3-WK1915
This antibody is a rabbit recombinant antibody against mouse AGER. It was developed by immunization of rabbit with recombinant mouse AGER protein and then was produced as a recombinant antibody. The isotype of this product is rabbit IgG. R18-9X-4 and R38-7F-9 were identified as antibody pair for sandwich ELISA. As a detection antibody, the clone R38-7F-9 can be used in ELISA analysis to identify mouse AGER.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line MCF7
Immunofluorescent staining of human cell line MCF7 shows localization to nucleoli fibrillar center & cell junctions.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/64436/1232_G12_3_selected.jpg
Normal Tissue
Figure 2 Lung
Alveolar cells type I
Staining: High
Intensity: Strong
Quantity:>75%
Alveolar cells type II
Staining: Medium
Intensity: Strong
Quantity: <25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/69474/168057_A_2_4.jpg
RNA Expression
Figure 3 RNA cell line category: Cell line enhanced (HEK93, JURKAT, RPTEC TERT1, U-266/70, U-266/84)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000204305-AGER
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Specifications
- Immunogen
- Recombinant mouse AGER protein
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Mouse AGER
- Species Reactivity
- Mouse
- Clone
- R38-7F-9
- Applications
- ELISA
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Aggregation
- < 5%
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 0.01M PBS, pH 7.2
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- RAGE
- Gene ID
- 11596
- UniProt ID
- Q62151
- Long Name
- Advanced glycosylation end product-specific receptor
- Cellular Localization
- Membrane
- Post Translation Modifications
- Phosphorylated on its cytoplasmic domain by PKCzeta/PRKCZ upon ligand binding.
Targeted by the ubiquitin E3 ligase subunit FBXO10 to mediate its ubiquitination and degradation.
- Protein Refseq
- NP_001258351.1
- Function
- Cell surface pattern recognition receptor that senses endogenous stress signals with a broad ligand repertoire including advanced glycation end products, S100 proteins, high-mobility group box 1 protein/HMGB1, amyloid beta/APP oligomers, nucleic acids, phospholipids and glycosaminoglycans.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Capture antibody
Isotype Control
- CAT
- Product Name
Secondary Antibody
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| CAT | Product Name | Application | Type |
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