Recombinant Rabbit Anti-CCL5 Capture Antibody (clone R06-8V9)
CAT#: VS3-WK1754
This antibody is a rabbit recombinant antibody against human CCL5. It was developed by immunization of rabbit with recombinant human CCL5 protein and then was produced as a recombinant antibody. The isotype of this product is rabbit IgG. The sandwich ELISA was established using matched antibody pair R06-8V9 and R03-8P5. The clone R06-8V9 can be used as a capture antibody in ELISA analysis to identify human CCL5.
Gene Expression
Normal Tissue
Figure 1 High expression in bone marrow.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/78447/168177_B_4_4_val_selected.jpg
Normal Tissue
Figure 2 Low expression in skin 1.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/78447/168177_B_7_1_val_selected.jpg
Normal Tissue
Figure 3 Colon
Enterocytes - Mucosal lymphoid cells Staining: Medium Intensity: Strong Quantity: <25%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/78447/168177_A_8_3.jpg
Normal Tissue
Figure 4 Kidney
Cells in tubules Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/78447/168177_A_8_5.jpg
RNA Expression
Figure 5 RNA cell line category: Cell line enhanced (HL-60, NB-4, THP-1, U-937)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000271503-CCL5
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (HL-60, NB-4, THP-1, U-937)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000271503-CCL5
❮
❯
Specifications
- Immunogen
- Recombinant human CCL5 protein
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human CCL5
- Species Reactivity
- Human
- Clone
- R06-8V9
- Applications
- ELISA
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Aggregation
- < 5%
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 0.01M PBS, pH 7.2
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- C-C Motif Chemokine Ligand 5; SIS-Delta; Regulated Upon Activation, Normally T-Expressed, And Presumably Secreted; Small Inducible Cytokine Subfamily A (Cys-Cys), Member 5; Eosinophil Chemotactic Cytokine; Chemokine (C-C Motif) Ligand 5; T-Cell Specific Protein P288; Beta-Chemokine RANTES; D17S136E; TCP228; SCYA5
- Gene ID
- 6352
- UniProt ID
- P13501
- Long Name
- C-C Motif Chemokine Ligand 5
- Sequence Similarities
- Belongs to the intercrine beta (chemokine CC) family.
- Cellular Localization
- Secreted
- Post Translation Modifications
- N-terminal processed form RANTES(3-68) is produced by proteolytic cleavage, probably by DPP4, after secretion from peripheral blood leukocytes and cultured sarcoma cells.
N-terminal processed form RANTES(4-68) is produced by proteolytic cleavage by cathepsin CTSG.
- Protein Refseq
- NP_002976.2
- Function
- Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant RANTES protein induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form RANTES(3-68) acts as a natural chemotaxis inhibitor and is a more potent inhibitor of HIV-1-infection. The second processed form RANTES(4-68) exhibits reduced chemotactic and HIV-suppressive activity compared with RANTES(1-68) and RANTES(3-68).
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Related Signaling Pathways
TNF Signaling Pathway
Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Detection antibody
Isotype Control
- CAT
- Product Name
Secondary Antibody
See other products for "CCL5"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-098CL | Human Anti-CCL5 Recombinant Antibody (TAB-098CL) | ELISA | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0487MZ | Chicken Anti-RANTES Polyclonal IgY | Indirect ELISA, WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-231CQ | Mouse Anti-CCL5 Recombinant Antibody (clone CBL636) | Neut | Mouse IgG2b |
| NEUT-232CQ | Recombinant Mouse Anti-CCL5 Antibody, Unconjugated | ELISA, IHC, Neut | IgG2b |
| NEUT-233CQ | Mouse Anti-CCL5 Recombinant Antibody (clone CBL009) | Neut, WB | Mouse IgG1 |
| NEUT-234CQ | Mouse Anti-CCL5 Recombinant Antibody (clone CBL421) | WB, Neut | Mouse IgG1 |
| NEUT-235CQ | Mouse Anti-CCL5 Recombinant Antibody (clone CBL428) | WB, ELISA(Cap), Neut | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-459CQ | Rat Anti-CCL5 Recombinant Antibody (clone 53405.111) | IF, Inhib | Rat IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0511 | Hi-Affi™ Rabbit Anti-CCL5 Recombinant Antibody (clone DS511AB) | ICC, WB | Rabbit IgG |
| MOR-4545 | Hi-Affi™ Rabbit Anti-CCL5 Recombinant Antibody (clone TH54DS) | WB, IHC-P | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0378LY | Human Anti-CCL5 Recombinant Antibody (clone 1E4) | ELISA, Inhib | Human IgG1 |
| HPAB-0379LY | Human Anti-CCL5 Recombinant Antibody (clone C8) | ELISA, Inhib | Human IgG1 |
| HPAB-0380LY | Human Anti-CCL5 Recombinant Antibody (clone 1D9) | ELISA, Inhib, FC, IF | Human IgG1 |
| MRO-1320-CN | Rabbit Anti-CCL5 Recombinant Antibody (clone JM03-45) | WB, IF, IHC | Rabbit IgG |
| VS-0923-FY34 | Recombinant Mouse Anti-CCL5 Antibody (VS-0923-FY34) | ELISA, WB | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0378LY-S(P) | Human Anti-CCL5 Recombinant Antibody (clone 1E4); scfv Fragment | ELISA, Inhib | Human scfv |
| HPAB-0379LY-S(P) | Human Anti-CCL5 Recombinant Antibody (clone C8); scfv Fragment | ELISA, Inhib | Human scfv |
| HPAB-0380LY-S(P) | Human Anti-CCL5 Recombinant Antibody (clone 1D9); scfv Fragment | ELISA, Inhib | Human scfv |
| HPAB-0381LY-S(P) | Human Anti-CCL5 Recombinant Antibody (clone D9); scfv Fragment | ELISA, Inhib | Human scfv |
| HPAB-0382LY-S(P) | Human Anti-CCL5 Recombinant Antibody (clone 3E7); scfv Fragment | ELISA, Inhib | Human scfv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0378LY-F(E) | Human Anti-CCL5 Recombinant Antibody (clone 1E4); Fab Fragment | ELISA, Inhib | Human Fab |
| HPAB-0379LY-F(E) | Human Anti-CCL5 Recombinant Antibody (clone C8); Fab Fragment | ELISA, Inhib | Human Fab |
| HPAB-0380LY-F(E) | Human Anti-CCL5 Recombinant Antibody (clone 1D9); Fab Fragment | ELISA, Inhib | Human Fab |
| HPAB-0381LY-F(E) | Human Anti-CCL5 Recombinant Antibody (clone D9); Fab Fragment | ELISA, Inhib | Human Fab |
| HPAB-0382LY-F(E) | Human Anti-CCL5 Recombinant Antibody (clone 3E7); Fab Fragment | ELISA, Inhib | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY69 | Mouse Anti-NHP CCL5 Recombinant Antibody (VS-1024-XY69) | WB, ELISA | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC572 | Recombinant Anti-CCL5 Vesicular Antibody, EV Displayed (VS-0425-YC572) | ELISA, FC, Inhib, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1069 | Anti-CCL5 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0825-YC33 | SmartAb™ Recombinant Anti-CCL5 pH-dependent Antibody (VS-0825-YC33) | ELISA | Human IgG |
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