Recombinant Anti-CDH3 Vesicular Antibody, EV Displayed (VS-0425-YC427)
CAT#: VS-0425-YC427
The Recombinant Anti-CDH3 Vesicular Antibody, EV Displayed (VS-0425-YC427) is an antibody-displaying extracellular vesicle (Ab-EV). The product combines the benefits of both extracellular vesicle (EV) and antibody (Ab) which can guide the decorated EVs to CDH3-expressed cells or tissues. The CDH3 is a cadherin protein involved in cell adhesion pathways and linked to conditions like ectodermal dysplasia.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line CACO-2
Immunofluorescent staining of human cell line CACO-2 shows localization to plasma membrane & cell junctions.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1767/1032_G9_1_selected.jpg
Normal Tissue
Figure 2 Skin 1
High expression
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1767/8164_B_8_1_val_selected.jpg
Normal Tissue
Figure 3 Oral mucosa
Squamous epithelial cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1767/8164_A_8_1.jpg
Normal Tissue
Figure 4 Colon
Glandular cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1767/8164_A_8_3.jpg
Normal Tissue
Figure 5 Liver
Cholangiocytes Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1767/8164_A_7_4.jpg
Normal Tissue
Figure 6 Kidney
Collecting ducts Staining: Medium Intensity: Moderate Quantity:>75% Distal tubules Staining: Medium Intensity: Moderate Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1767/8164_A_8_5.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (A-431, HaCaT, HBEC3-KT, hTCEpi, hTERT-HME1, RPTEC TERT1)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000062038-CDH3
❮
❯
Recombinant Antibody
- Application
- ELISA, FC, Inhib, Cell-uptake
- Product Type
- Ab-Fc-EVs
- Antibody Quantification (Ab/EV)
- ~100 Ab/EV
- Target
- CDH3
- Host Animal
- Mouse
- Antibody Isotype
- IgG
- Species Reactivity
- Human
- Expression Cell
- Mammalian cell
Engineered EVs
- EV-sorting domain
- CD63
- Fc-binding domain
- Protein A
- EV Size
- 30~150 nm
- Producing Cell
- HEK293F
- Isolation Method
- Gradient centrifugation
- Purification
- qEV size exclusion chromatography
- Concentration
- 1 x 10¹⁰
- Size
- 1 mL
- Buffer
- PBS
- Storage
- Store at -80°C for 12 months
Target
- Full Name
- Cadherin 3
- Biological Process
- Cell adhesion, Sensory transduction, Vision
- Cellular Localization
- Plasma membrane, Cell Junctions
- Introduction
- CDH3 (Cadherin 3) is a Protein Coding gene. Diseases associated with CDH3 include Ectodermal Dysplasia, Ectrodactyly, And Macular Dystrophy Syndrome and Hypotrichosis, Congenital, With Juvenile Macular Dystrophy. Among its related pathways are ERK Signaling and Overview of nanoparticle effects. Gene Ontology (GO) annotations related to this gene include calcium ion binding. An important paralog of this gene is CDH1.
- Alternative Names
- CDHP, PCAD
- Gene ID
- 1001
- UniProt ID
- P22223
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Datasheet
MSDS
COA
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0943CL | Mouse Anti-CDH3 Recombinant Antibody (TAB-0943CL) | Inhib | Mouse IgG |
| TAB-0943CL-S(P) | Mouse Anti-CDH3 Recombinant Antibody; scFv Fragment (TAB-0943CL-S(P)) | SDS-PAGE | Mouse scFv |
| TAB-0943CL-F(E) | Mouse Anti-CDH3 Recombinant Antibody; Fab Fragment (TAB-0943CL-F(E)) | SDS-PAGE | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0944CL | Human Anti-CDH3 Recombinant Antibody (TAB-0944CL) | ELISA | Human IgG |
| TAB-0944CL-S(P) | Human Anti-CDH3 Recombinant Antibody; scFv Fragment (TAB-0944CL-S(P)) | ELISA | Human scFv |
| TAB-0944CL-F(E) | Human Anti-CDH3 Recombinant Antibody; Fab Fragment (TAB-0944CL-F(E)) | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-446CQ | Mouse Anti-CDH3 Recombinant Antibody (VMC175) | ICC, IF, WB, IP, Block | Mouse IgG1 |
| NEUT-447CQ | Mouse Anti-CDH3 Recombinant Antibody (clone NCC-CAD-299) | IHC-Fr, Inhib, WB | Mouse IgG1 |
| NEUT-448CQ | Rat Anti-Cdh3 Recombinant Antibody (clone PCD-1) | ELISA, Inhib, IF, WB, IHC-P, IHC-Fr, FC, IV | Rat IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0619 | Hi-Affi™ Rabbit Anti-CDH3 Recombinant Antibody (clone DS619AB) | WB, IP, FC, IHC-P, ICC, IF | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0142CQ-F(E) | Human Anti-CDH3 Recombinant Antibody (clone 194-b09); Fab Fragment | ELISA, FC | Human Fab |
| PFBC-251 | Mouse Anti-CDH3 Recombinant Antibody (clone TSP7); Fab Fragment | ELISA, Inhib, Live cell imaging | Mouse Fab |
| PFBC-252 | Mouse Anti-CDH3 Recombinant Antibody (clone TSP11); Fab Fragment | ELISA, Inhib, Live cell imaging | Mouse Fab |
| HPAB-2071LY-F(E) | Human Anti-CDH3 Recombinant Antibody; Fab Fragment (HPAB-2071LY-F(E)) | ELISA | Human Fab |
| HPAB-0390-FY-F(E) | Human Anti-CDH3 Recombinant Antibody; Fab Fragment (HPAB-0390-FY-F(E)) | IHC | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABC-251 | Mouse Anti-CDH3 Recombinant Antibody (clone TSP7) | ELISA, Inhib, Live cell imaging | Mouse IgG |
| PABC-252 | Mouse Anti-CDH3 Recombinant Antibody (clone TSP11) | ELISA, Inhib, Live cell imaging | Mouse IgG |
| PABC-253 | Mouse Anti-CDH3 Recombinant Antibody (clone TSP5) | ELISA, Inhib, Live cell imaging | Mouse IgG |
| HPAB-2071LY | Human Anti-CDH3 Recombinant Antibody (HPAB-2071LY) | ELISA | Human IgG |
| HPAB-0390-FY | Human Anti-CDH3 Recombinant Antibody (HPAB-0390-FY) | IHC | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBC-251 | Mouse Anti-CDH3 Recombinant Antibody (clone TSP7); scFv Fragment | ELISA, Inhib, Live cell imaging | Mouse scFv |
| HPAB-2071LY-S(P) | Human Anti-CDH3 Recombinant Antibody; scFv Fragment (HPAB-2071LY-S(P)) | ELISA | Human scFv |
| HPAB-0400-YJ-S(P) | Human Anti-CDH3 Recombinant Antibody; scFv Fragment (HPAB-0400-YJ-S(P)) | ELISA, FuncS | Human scFv |
| HPAB-0401-YJ-S(P) | Human Anti-CDH3 Recombinant Antibody; scFv Fragment (HPAB-0401-YJ-S(P)) | ELISA, FuncS | Human scFv |
| HPAB-0390-FY-S(P) | Human Anti-CDH3 Recombinant Antibody; scFv Fragment (HPAB-0390-FY-S(P)) | IHC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN0513 | PE-A*24:02/Human CDH3 (DYLNEWGSRF) MHC Tetramer | FCM, IHC | |
| MHC-CN0514 | APC-A*24:02/Human CDH3 (DYLNEWGSRF) MHC Tetramer | FCM, IHC | |
| MHC-CN0515 | FITC-A*24:02/Human CDH3 (DYLNEWGSRF) MHC Tetramer | FCM, IHC | |
| MHC-CN0516 | A*24:02/Human CDH3 (DYLNEWGSRF) MHC Tetramer | FCM, IHC | |
| MHC-YF359 | A*24:02/Human CDH3 (DYLNEWGSRF) MHC Pentamer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY1295 | Anti-CDH3 Immunohistochemistry Kit | IHC |
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