PE-A*24:02/Human CDH3 (DYLNEWGSRF) MHC Tetramer

Name: PE-A*24:02/Human CDH3 (DYLNEWGSRF) MHC Tetramer
SKU: MHC-CN0513
Rating: 5 (1 reviews)

CAT#: MHC-CN0513

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line CACO-2

Immunofluorescent staining of human cell line CACO-2 shows localization to plasma membrane & cell junctions.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1767/1032_G9_1_selected.jpg

Normal Tissue Figure 2 Skin 1

High expression

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1767/8164_B_8_1_val_selected.jpg

Normal Tissue Figure 3 Oral mucosa

Squamous epithelial cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1767/8164_A_8_1.jpg

Normal Tissue Figure 4 Colon

Glandular cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1767/8164_A_8_3.jpg

Normal Tissue Figure 5 Liver

Cholangiocytes Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1767/8164_A_7_4.jpg

Normal Tissue Figure 6 Kidney

Collecting ducts Staining: Medium Intensity: Moderate Quantity:>75% Distal tubules Staining: Medium Intensity: Moderate Quantity:>75%

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/1767/8164_A_8_5.jpg

RNA Expression Figure 7 RNA cell line category: Cell line enhanced (A-431, HaCaT, HBEC3-KT, hTCEpi, hTERT-HME1, RPTEC TERT1)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000062038-CDH3

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Specifications

Allele
A*24:02

Class
Class I

MHC Species
Human

Antigen
CDH3

Antigen Species
Human

Peptide
DYLNEWGSRF

Conjugate
PE

Application
FCM, IHC

Target

Antigen Introduction
This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene are associated with hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (EEMS). [provided by RefSeq, Nov 2015]

Alternative Names
CDHP; HJMD; PCAD

Gene ID
1001

UniProt ID
P22223

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Datasheet

Datasheet - MHC-CN0513.pdf

MSDS

MSDS - MHC-CN0513.pdf

COA

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Protocol & Troubleshooting

Immunohistochemistry (IHC)

We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.

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