APC-A*24:02/Human CDH3 (DYLNEWGSRF) MHC Tetramer (CAT#: MHC-CN0514)
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line CACO-2
(Immunofluorescent staining of human cell line CACO-2 shows localization to plasma membrane & cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1767/1032_G9_1_selected.jpg
(Immunofluorescent staining of human cell line CACO-2 shows localization to plasma membrane & cell junctions.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1767/1032_G9_1_selected.jpg
Figure 2 Skin 1
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1767/8164_B_8_1_val_selected.jpg
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1767/8164_B_8_1_val_selected.jpg
Figure 3 Oral mucosa
(Squamous epithelial cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1767/8164_A_8_1.jpg
(Squamous epithelial cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1767/8164_A_8_1.jpg
Figure 4 Colon
(Glandular cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1767/8164_A_8_3.jpg
(Glandular cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1767/8164_A_8_3.jpg
Figure 5 Liver
(Cholangiocytes Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1767/8164_A_7_4.jpg
(Cholangiocytes Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1767/8164_A_7_4.jpg
Figure 6 Kidney
(Collecting ducts Staining: Medium Intensity: Moderate Quantity:>75% Distal tubules Staining: Medium Intensity: Moderate Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1767/8164_A_8_5.jpg
(Collecting ducts Staining: Medium Intensity: Moderate Quantity:>75% Distal tubules Staining: Medium Intensity: Moderate Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1767/8164_A_8_5.jpg
Figure 7 RNA cell line category: Cell line enhanced (A-431, HaCaT, HBEC3-KT, hTCEpi, hTERT-HME1, RPTEC TERT1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000062038-CDH3
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000062038-CDH3
Specifications
- Allele
- A*24:02
- Class
- Class I
- MHC Species
- Human
- Antigen
- CDH3
- Antigen Species
- Human
- Peptide
- DYLNEWGSRF
- Conjugate
- APC
- Application
- FCM, IHC
Target
- Antigen Introduction
- This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene are associated with hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (EEMS). [provided by RefSeq, Nov 2015]
- Alternative Names
- CDHP; HJMD; PCAD
- Gene ID
- 1001
- UniProt ID
- P22223
Downloads
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