Recombinant Anti-CXCR2 Vesicular Antibody, EV Displayed (VS-0425-YC259) (CAT#: VS-0425-YC259)

• Application
• ELISA, FC, Inhib, Cell-uptake

• Product Type
• Ab-Fc-EVs

• Antibody Quantification (Ab/EV)
• ~100 Ab/EV

• Target
• CXCR2

• Host Animal
• Human

• Antibody Isotype
• IgG1

• Expression Cell
• Mammalian cell

• EV-sorting domain
• CD63

• Fc-binding domain
• z domain

• EV Size
• 30~150 nm

• Producing Cell
• HEK293F

• Isolation Method
• Gradient centrifugation

• Purification
• qEV size exclusion chromatography

• Binding Affinity
• Kd = 0.85 µg/mL

• Concentration
• 1 x 10¹⁰

• Size
• 1 mL

• Buffer
• PBS

• Storage
• Store at -80°C for 12 months

• Full Name
• C-X-C motif chemokine receptor 2

• Biological Process
• Chemotaxis

• Molecular Function
• G-protein coupled receptor, Receptor, Transducer

• Cellular Localization
• Plasma membrane, Nucleoplasm, Microtubules, Mitotic spindle

• Introduction
• CXCR2 (C-X-C Motif Chemokine Receptor 2) is a Protein Coding gene. Diseases associated with CXCR2 include Autosomal Recessive Severe Congenital Neutropenia Due To Cxcr2 Deficiency and Neutrophil Migration. Among its related pathways are Akt Signaling and Innate Immune System. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and C-X-C chemokine receptor activity. An important paralog of this gene is CXCR1.

• Alternative Names
• CD182, CMKAR2, IL8RB

• Gene ID
• 3579

• UniProt ID
• P25025

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