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    CXCR2

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    Anti-CXCR2 Products

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    For Research Use Only. Not For Clinical Use.


    CXCR2 (C-X-C Motif Chemokine Receptor 2) is a Protein Coding gene. Diseases associated with CXCR2 include Autosomal Recessive Severe Congenital Neutropenia Due To Cxcr2 Deficiency and Neutrophil Migration. Among its related pathways are Akt Signaling and Innate Immune System. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and C-X-C chemokine receptor activity. An important paralog of this gene is CXCR1.
    Protein class

    Cancer-related genes, CD markers, G-protein coupled receptors

    Predicted location

    Intracellular, Membrane (different isoforms)

    Single cell type specificity

    Cell type enhanced (NK-cells, dendritic cells, Squamous epithelial cells, Alveolar cells type 2, granulocytes)

    Immune cell specificity

    Immune cell enriched (neutrophil)

    Cell line specificity

    Group enriched (BEWO, HL-60, HMC-1, THP-1, U-937)

    Molecular function

    G-protein coupled receptor, Receptor, Transducer

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