Anti-Human CXCR2 Recombinant Antibody (CX2-Mab#5)
CAT#: TAB-123MZ
This antibody which binds to specific extracellular domains of CXCR2 may be used as a drug for the treatment or prophylaxis of inflammatory disorders or cancer.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line THP-1
Immunofluorescent staining of human cell line THP-1 shows localization to plasma membrane, microtubules & mitotic spindle.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/31999/1855_E6_15_cr5ad88637398d2_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line THP-1
Immunofluorescent staining of human cell line THP-1 shows localization to nucleoplasm & plasma membrane.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/32017/1855_F6_25_cr5ad88701bb05e_selected.jpg
Normal Tissue
Figure 3 Cerebral cortex
Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/32017/139603_B_9_5.jpg
Normal Tissue
Figure 4 Lymph node
Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/32017/139603_A_8_8.jpg
Normal Tissue
Figure 5 High expression in spleen
Cells in red pulp Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/32017/139603_B_9_4.jpg
RNA Expression
Figure 6 RNA cell line category: Group enriched (BEWO, HL-60, HMC-1, THP-1, U-937)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000180871-CXCR2
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Specifications
- Host Species
- Human
- Derivation
- Phage display library
- Type
- Human antibody
- Antibody Isotype
- lgG1
- Specificity
- Human
- Clone
- CX2-Mab#5
- Applications
- Enzyme-linked Immunosorbent Assay
- Related Disease
- Inflammatory disorders or cancer
Target
- Alternative Names
- CXCR2; chemokine (C-X-C motif) receptor 2; CD182; IL8R2; IL8RA; IL8RB; CMKAR2; CDw128b; C-X-C chemokine receptor type 2; CXC-R2; CXCR-2; IL-8R B; GRO/MGSA receptor; IL-8 receptor type 2; interleukin 8 receptor B; chemokine (CXC) receptor 2; interleukin 8 receptor, beta; interleukin 8 receptor type 2; interleukin-8 receptor type B; CXCR2 gene for IL8 receptor type B; high affinity interleukin-8 receptor B
- Gene ID
- 3579
- UniProt ID
- P25025
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
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